European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice Tập 73 Số 4 - Trang 195-221 - 2015
Jeanne D. Johansen, Kristiina Aalto‐Korte, Tove Agner, Klaus E. Andersen, Andreas J. Bircher, M. Bruze, Alicia Cannavó, Ana M. Giménez‐Arnau, Margarida Gonçalo, An Goossens, Swen Malte John, Carola Lidén, Magnus Lindberg, Vera Mahler, Mihály Matura, Thomas Rustemeyer, Jørgen Serup, Radosław Śpiewak, Jacob P. Thyssen, M. Vigan, Ian R. White, Mark Wilkinson, Wolfgang Uter
SummaryThe present guideline summarizes all aspects of patch testing for the
diagnosis of contact allergy in patients suspected of suffering, or having been
suffering, from allergic contact dermatitis or other delayed‐type
hypersensitivity skin and mucosal conditions. Sections with brief descriptions
and discussions of different pertinent topics are followed by a highlighted
short practical recomm... hiện toàn bộ
Updating the maximization test for identifying contact allergens Tập 1 Số 4 - Trang 231-239 - 1975
Albert M. Kligman, William L. Epstein
The maximization test for detecting contact allergens has proved to possess both
sensitivity and specificity. However, modifications have become necessary
because of excessive irritancy reactions to sodium lauryl sulfate. Fewer
exposures are now recommended during induction and lower concentrations for
challenge patch testing. Pre‐testing of each subject in the panel is now
standard procedure. The... hiện toàn bộ
Guidelines for performing skin tests withdrugs in the investigation of cutaneous adverse drug reactions Tập 45 Số 6 - Trang 321-328 - 2001
A. Barbaud, Margarida Gonçalo, Derk P. Bruynzeel, Andreas J. Bircher
Skin testing with a suspected drug has been reported to be helpful in
determining the cause of cutaneous adverse drug reactions (CADR). Many isolated
reports of positive drug skin tests are published, but without detailed
information concerning the clinical features of the CADR and the method used in
performing drug skin tests, such data are not very informative. A working party
of the European So... hiện toàn bộ
The repeated open application test (ROAT) Tập 14 Số 4 - Trang 221-227 - 1986
Matti Hannuksela, H. Salo
Repeated open application tests (ROATs) were performed with common ingredients
of vehicles in 86 patients with contact dermatitis. The substances were applied
twice daily for 7 days to the flexor aspect of the forearm near the cubital
fossa, unless dermatitis appeared earlier. Of the patients with a questionable
(?+) patch test result, 44% were positive in ROATs. The corresponding figure was
80% i... hiện toàn bộ
Adverse reactions to fragrances Tập 36 Số 2 - Trang 57-86 - 1997
Anton C. de Groot, P J Frosch
This article reviews side‐effects of fragrance materials present in cosmetics
with emphasis on clinical aspects: epidemiology, type, of adverse reactions,
clinical picture, diagnostic procedures, and the sensitizers. Considering the
ubiquitous occurrence of fragrance materials, the risk of side‐effects is small.
In absolute numbers, however, fragrance allergy is common, affecting
approximately 1% ... hiện toàn bộ
Air oxidation of d‐limonene (the citrus solvent) creates potent allergens Tập 26 Số 5 - Trang 332-340 - 1992
Ann‐Therése Karlberg, Kerstin Magnusson, Ulrika Nilsson
Products containing as much as 95% of d‐limonene are used for, e.g., degreasing
metal before industrial painting and for cleaning assemblies. Experimental
studies on the sensitizing potential of limonene show diverging results. In a
previous study, we found that the sensitizing potential of d‐limonene increased
with prolonged air exposure. The aim of 1 his study was to make further chemical
analys... hiện toàn bộ
The local lymph node assay: past, present and future Tập 47 Số 6 - Trang 315-328 - 2002
Ian Kimber, Rebecca J. Dearman, David A. Basketter, Cindy A. Ryan, G. Frank Gerberick
The local lymph node assay (LLNA) was developed originally as a method for the
identification of chemicals that have the potential to cause skin sensitization
and allergic contact dermatitis. The assay is based on an understanding that the
acquisition of contact sensitization is associated with, and dependent upon, the
stimulation by chemical allergens of lymphocyte proliferative responses in
skin... hiện toàn bộ
Patch testing with fragrances: results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes Tập 33 Số 5 - Trang 333-342 - 1995
Wolfgang Uter, Beate Pilz, K. E. Andersen, D. Burrows, José G. Camarasa, A. Dooms‐Goossens, G. Ducombs, Thomas Fuchs, M. Hannusksela, Jean‐Marie Lachapelle, A. Lahti, Howard I. Maibach, Torkil Menné, R. J. G. Rycroft, S. Shaw, Jan E. Wahlberg, Ian R. White, J. D. Wilkinson
The objective of this study was to determine the frequency of reactivity to a
series of commonly fragrances in dermatological patients. A total of 48
fragrances (FF) were chosen, based on the publication of Fenn in 1989 in which
the lop 25 constituents of 3 types (1. perfumes, 2. household products, 3.
soaps) of 400 commercial products on the US market had been determined. In a
pilot study on a to... hiện toàn bộ
Fragrance chemicals in domestic and occupational products Tập 45 Số 4 - Trang 221-225 - 2001
S. C. Rastogi, S. Heydorn, Jeanne Duus Johansen, D A Basketter
Epidemiological studies have described an increasing prevalence of fragrance
allergy and indicated an association with hand eczema. 59 domestic and
occupational products intended for hand exposure were subjected to gas
chromatography‐mass spectrometric (GC‐MS) analyses to test the hypothesis that
fragrance chemicals known to have the potential to cause contact allergy but not
included in fragrance... hiện toàn bộ
The angry back syndrome: eczema creates eczema Tập 1 Số 4 - Trang 193-194 - 1975
John C. Mitchell
False positive patch test reactions are common when the skin of the back is
hyper‐reactive, Such reactions can obscure or invalidate observations of
multiple specific sensitivity and of cross‐sensitivity to contactants. The
pathogenesis of the hyper‐reactive skin (‘angry back’) is discussed and a
mechanism postulated for the notion that eczema at certain sites can provoke an
eczematous tendency at... hiện toàn bộ