Cell Proliferation
SCIE-ISI SCOPUS (1968-1982,1984-2025)
0960-7722
1365-2184
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
Medicine (miscellaneous)Cell Biology
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Fibroblastic response to treatment with different preparations rich in growth factors
Tập 42 Số 2 - Trang 162-170 - 2009
AbstractObjectives: Preparations rich in growth factors (PRGF) release them
plus bioactive proteins at localized sites, with the aim of triggering healing
and regenerative processes. The prevailing paradigm suggests that their
influence on proliferation, angiogenesis and the extracellular matrix synthesis
is minimal. However, variations in their composition and impact on different
cell phenotypes...
Stem cells and neurological diseases
Tập 41 Số s1 - Trang 94-114 - 2008
Abstract. Cells of the central nervous system were once thought to be incapable
of regeneration. This dogma has been challenged in the last decade with studies
showing new, migrating stem cells in the brain in many rodent injury models and
findings of new neurones in the human hippocampus in adults. Moreover, there are
reports of bone marrow‐derived cells developing neuronal and vascular phenotyp...
Hepatic stem cells: from inside and outside the liver?
Tập 37 Số 1 - Trang 1-21 - 2004
Abstract. The liver is normally proliferatively quiescent, but hepatocyte loss
through partial hepatectomy, uncomplicated by virus infection or inflammation,
invokes a rapid regenerative response from all cell types in the liver to
perfectly restore liver mass. Moreover, hepatocyte transplants in animals have
shown that a certain proportion of hepatocytes in foetal and adult liver can
clonally e...
MicroRNA‐494 suppresses cell proliferation and induces senescence in A549 lung cancer cells
Tập 45 Số 1 - Trang 32-38 - 2012
AbstractObjectives: MicroRNAs (miRNAs) are small functional RNAs that regulate
mRNAs for degradation or translational suppression. In the present study, we
aimed to reveal functional importance of miRNA‐494 (miR‐494) in A549 human lung
cancer cells.Materials and methods: We established A549 cells that
constitutively expressed miR‐494. Next, we sought to investigate insulin‐like
growth factor 2 m...
Cell kinetic status of haematopoietic stem cells
Tập 34 Số 2 - Trang 71-83 - 2001
Abstract.The haematopoietic stem cell (HSC) population supports a tremendous
cellular production over the course of an animal’s lifetime, e.g. adult humans
produce their body weight in red cells, white cells and platelets every 7 years,
while the mouse produces about 60% of its body weight in the course of a 2 year
lifespan. Understanding how the HSC population carries this out is of interest
and ...
Chitosan enhances mineralization during osteoblast differentiation of human bone marrow-derived mesenchymal stem cells, by upregulating the associated genes
Tập 44 Số 6 - Trang 537-549 - 2011
A quantitative method for the analysis of mammalian cell proliferation in culture in terms of dividing and non‐dividing cells
Tập 28 Số 3 - Trang 137-144 - 1995
AbstractThe application of the exponential growth equation is the standard
method employed in the quantitative analyses of mammalian cell proliferation in
culture. This method is based on the implicit assumption that, within a cell
population under study, all division events give rise to daughter cells that
always divide. When a cell population does not adhere to this assumption, use of
the expone...
Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation
Tập 42 Số 4 - Trang 471-484 - 2009
AbstractIntroduction: In vitro expansion and differentiation of mesenchymal
stem cells (MSC) rely on specific environmental conditions, and investigations
have demonstrated that one crucial factor is oxygen environment.Objectives: In
order to understand the impact of oxygen tension on MSC culture and chondrogenic
differentiation in vitro, we developed a mathematical model of these processes
and ...
Diffusion‐limited binding explains binary dose response for local arterial and tumour drug delivery
Tập 42 Số 3 - Trang 348-363 - 2009
AbstractBackground: Local drug delivery has transformed medicine, yet it
remains unclear how drug efficacy depends on physicochemical properties and
delivery kinetics. Most therapies seek to prolong release, yet recent studies
demonstrate sustained clinical benefit following local bolus endovascular
delivery.Objectives: The purpose of the current study was to examine interplay
between drug dose,...