Fibroblastic response to treatment with different preparations rich in growth factorsCell Proliferation - Tập 42 Số 2 - Trang 162-170 - 2009
Eduardo Anitua, Mikel Sánchez, Mar Zalduendo, María de la Fuente, Roberto Prado, Gorka Orive, Isabel Andı́a
AbstractObjectives: Preparations rich in growth factors (PRGF) release them
plus bioactive proteins at localized sites, with the aim of triggering healing
and regenerative processes. The prevailing paradigm suggests that their
influence on proliferation, angiogenesis and the extracellular matrix synthesis
is minimal. However, variations in their composition and impact on different
cell phenotypes... hiện toàn bộ
A quantitative method for the analysis of mammalian cell proliferation in culture in terms of dividing and non‐dividing cellsCell Proliferation - Tập 28 Số 3 - Trang 137-144 - 1995
James L. Sherley, Patrizia B. Stadler, J.S. Stadler
AbstractThe application of the exponential growth equation is the standard
method employed in the quantitative analyses of mammalian cell proliferation in
culture. This method is based on the implicit assumption that, within a cell
population under study, all division events give rise to daughter cells that
always divide. When a cell population does not adhere to this assumption, use of
the expone... hiện toàn bộ
microRNA exchange via extracellular vesicles in cancerCell Proliferation - Tập 53 Số 11 - 2020
Luyen Tien Vu, Jinhua Gong, Thach Tuan Pham, Yeokyeong Kim, Minh T. N. Le
AbstractCells utilize different means of inter‐cellular communication to
function properly. Here, we review the crosstalk between cancer cells and their
surrounding environment through microRNA (miRNA)‐containing extracellular
vesicles (EVs). The current findings suggest that the export of miRNAs and
uptake of miRNA‐containing EVs might be an active process. As
post‐transcriptional regulators of g... hiện toàn bộ
Hepatic stem cells: from inside and outside the liver?Cell Proliferation - Tập 37 Số 1 - Trang 1-21 - 2004
Malcolm Alison, Pamela Vig, Francesco Paolo Russo, Brian Bigger, Eunice Amofah, Michael Themis, Stuart J. Forbes
Abstract. The liver is normally proliferatively quiescent, but hepatocyte loss
through partial hepatectomy, uncomplicated by virus infection or inflammation,
invokes a rapid regenerative response from all cell types in the liver to
perfectly restore liver mass. Moreover, hepatocyte transplants in animals have
shown that a certain proportion of hepatocytes in foetal and adult liver can
clonally e... hiện toàn bộ
F‐actin rearrangement is regulated by mTORC2/Akt/Girdin in mouse fertilized eggsCell Proliferation - Tập 49 Số 6 - Trang 740-750 - 2016
Dongcheng Wu, Dahai Yu, Xiuxia Wang, Bingzhi Yu
AbstractIn mouse fertilized eggs, correct assembly and distribution of the actin
cytoskeleton are intimately related to cleavage in early‐stage embryos. However,
in mouse fertilized eggs, mechanisms and involved factors responsible for
regulating the actin cytoskeleton are poorly defined. In this study, mTORC2,
PKB/Akt and Girdin were found to modulate division of mouse fertilized eggs by
regulati... hiện toàn bộ
MicroRNA‐30a promotes extracellular matrix degradation in articular cartilage via downregulation of Sox9Cell Proliferation - Tập 49 Số 2 - Trang 207-218 - 2016
Tingjie Chang, Jie Xie, Hongzhuo Li, Dong Li, Ping Liu, Yihe Hu
AbstractObjectivesSox9 has recently been reported to be a key mediator during
cartilage degradation in osteoarthritis (OA). Our aim was to clarify the role of
microRNA‐30a (miR‐30a) and its target gene Sox9 in regulation of extracellular
matrix (ECM) degradation in OA.Materials and methodsExpression of miR‐30a in
cartilage tissues and in primary chondrocytes from healthy and OA donors, was
determi... hiện toàn bộ