Cell Proliferation

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Chitosan enhances mineralization during osteoblast differentiation of human bone marrow-derived mesenchymal stem cells, by upregulating the associated genes
Cell Proliferation - Tập 44 Số 6 - Trang 537-549 - 2011
Smitha Mathews, Poonam Gupta, Ramesh Bhonde, S.M. Totey
A quantitative method for the analysis of mammalian cell proliferation in culture in terms of dividing and non‐dividing cells
Cell Proliferation - Tập 28 Số 3 - Trang 137-144 - 1995
James L. Sherley, Patrizia B. Stadler, J.S. Stadler
AbstractThe application of the exponential growth equation is the standard method employed in the quantitative analyses of mammalian cell proliferation in culture. This method is based on the implicit assumption that, within a cell population under study, all division events give rise to daughter cells that always divide. When a cell population does not adhere to t...... hiện toàn bộ
Comparison of methods based on annexin-V binding, DNA content or TUNEL for evaluating cell death in HL-60 and adherent MCF-7 cells
Cell Proliferation - Tập 32 Số 1 - Trang 25-37 - 1999
G. Del Bino, Zbigniew Darżynkiewicz, C. Degraef, R. Mosselmans, D. Fokan, P. Galand
Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation
Cell Proliferation - Tập 42 Số 4 - Trang 471-484 - 2009
Axel Krinner, Matthias Zscharnack, Augustinus Bader, Dirk Drasdo, Joerg Galle
AbstractIntroduction:  In vitro expansion and differentiation of mesenchymal stem cells (MSC) rely on specific environmental conditions, and investigations have demonstrated that one crucial factor is oxygen environment.Objectives:  In order to understand the impact of oxygen...... hiện toàn bộ
Caspase‐3‐mediated GSDME activation contributes to cisplatin‐ and doxorubicin‐induced secondary necrosis in mouse macrophages
Cell Proliferation - Tập 52 Số 5 - 2019
Feng‐Yi Mai, Pengyan He, Jiezhou Ye, Lihui Xu, Dong‐Yun Ouyang, Chenguang Li, Qiongzhen Zeng, Chenying Zeng, Chengcheng Zhang, Xian‐Hui He, Bo Hu
AbstractObjectiveInduction of secondary necrosis/pyroptosis contributes to the toxicity of chemotherapeutic drugs, in which gasdermin E (GSDME) plays critical roles. This study aimed to explore whether GSDME is involved in mediating the cytotoxic effects of cisplatin and doxorubicin on mouse macrophages.... hiện toàn bộ
Persistence of a chimerical phenotype after hepatocyte differentiation of human bone marrow mesenchymal stem cells
Cell Proliferation - Tập 41 Số 1 - Trang 36-58 - 2008
Philippe A. Lysy, David Campard, Françoise Smets, Jacques Malaise, Mohamed Mourad, Mustapha Najimi, Étienne Sokal
Abstract.  Objectives: Recent studies have suggested the potential of mesenchymal stem cells (MSCs) to differentiate into a hepatocyte‐like lineage. Here, we evaluate the efficacy of hepatocyte differentiation of MSCs by studying acquisition of hepatocyte‐like features together with alteration of the native mesenchymal phenotype. ... hiện toàn bộ
MicroRNA‐494 suppresses cell proliferation and induces senescence in A549 lung cancer cells
Cell Proliferation - Tập 45 Số 1 - Trang 32-38 - 2012
Hiroaki Ohdaira, Masaki Sekiguchi, Kenichi Miyata, Kenichi Yoshida
AbstractObjectives:  MicroRNAs (miRNAs) are small functional RNAs that regulate mRNAs for degradation or translational suppression. In the present study, we aimed to reveal functional importance of miRNA‐494 (miR‐494) in A549 human lung cancer cells.Materials and methods:  We established A549 cells that...... hiện toàn bộ
Mathematical model of heterogeneous cancer growth with an autocrine signalling pathway
Cell Proliferation - Tập 45 Số 5 - Trang 445-455 - 2012
G.‐M. Hu, Chih-Yu Lee, Yanhui CHEN, Ning-Ning Pang, Wen-Jer Tzeng
AbstractObjectivesCancer is a complex biological occurrence which is difficult to describe clearly and explain its growth development. As such, novel concepts, such as of heterogeneity and signalling pathways, grow exponentially and many mathematical models accommodating the latest knowledge have been proposed. Here, we present a ...... hiện toàn bộ
Inducing pluripotency in vitro: recent advances and highlights in induced pluripotent stem cells generation and pluripotency reprogramming
Cell Proliferation - Tập 48 Số 2 - Trang 140-156 - 2015
I. K. Rony, Abdul Baten, Justin A. Bloomfield, M. E. Islam, Lutfun Nahar, Khaleda Islam
AbstractInduced pluripotent stem cells (iPSCs) are considered patient‐specific counterparts of embryonic stem cells as they originate from somatic cells after forced expression of pluripotency reprogramming factors Oct4, Sox2, Klf4 and c‐Myc. hiện toàn bộ
Fibroblastic response to treatment with different preparations rich in growth factors
Cell Proliferation - Tập 42 Số 2 - Trang 162-170 - 2009
Eduardo Anitua, Mikel Sánchez, Mar Zalduendo, María de la Fuente, Roberto Prado, Gorka Orive, Isabel Andı́a
AbstractObjectives:  Preparations rich in growth factors (PRGF) release them plus bioactive proteins at localized sites, with the aim of triggering healing and regenerative processes. The prevailing paradigm suggests that their influence on proliferation, angiogenesis and the extracellular matrix synthesis is minimal. However, variations in t...... hiện toàn bộ
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