Annals of Pharmacotherapy
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Safety of COX-2 Inhibitors in Asthma Patients with Aspirin Hypersensitivity
Annals of Pharmacotherapy - Tập 37 Số 10 - Trang 1497-1501 - 2003
Objective To review the safety of cyclooxygenase-2 (COX-2) inhibitors in asthma
patients with aspirin hypersensitivity. Data Sources Clinical studies were
identified using MEDLINE (1966–September 2002). Key search terms included
cyclooxygenase inhibitors, aspirin, asthma, and hypersensitivity.
English-language articles were identified and included. References from the
identified articles were also...
Mixed Treatment Comparison of the Treatment Discontinuations of Biologic Disease-Modifying Antirheumatic Drugs in Adults with Rheumatoid Arthritis
Annals of Pharmacotherapy - Tập 46 Số 11 - Trang 1491-1505 - 2012
BACKGROUND: Introduction of biologic disease-modifying antirheumatic drugs
(DMARDs) has considerably changed treatment options for rheumatoid arthritis
(RA) over the past decade. Very little information is available on comparative
discontinuation rates of the biologics. OBJECTIVE: To compare treatment
discontinuations for 9 biologic DMARDs in adults with RA. METHODS: We searched
electronic databas...
Identifying and Assisting Low-Literacy Patients with Medication Use: A Survey of Community Pharmacies
Annals of Pharmacotherapy - Tập 39 Số 9 - Trang 1441-1445 - 2005
BACKGROUND: Nearly one-half of adult Americans have limited functional literacy
skills. Low patient literacy is associated with poor medication adherence and
health outcomes. However, little is known about how pharmacies address
literacy-related needs among patrons. OBJECTIVE: To determine the frequency with
which pharmacies identify and provide appropriate assistance to patients with
limited lite...
Geriatric Drug Therapy and Healthcare Utilization in the United Kingdom
Annals of Pharmacotherapy - Tập 36 Số 5 - Trang 797-803 - 2002
OBJECTIVE: To describe the use of prescription drug therapy, especially
polypharmacy, in an elderly general population; to relate that use to age,
gender, and different types of healthcare utilization; and to investigate the
influence of selection of different time windows on the result of the quantity
as well as the categories of drugs used. METHODS: Data on a sample of 5000
patients aged 65–90 y...
Prescription Drug Use, Diagnoses, and Healthcare Utilization among the Elderly
Annals of Pharmacotherapy - Tập 35 Số 9 - Trang 1004-1009 - 2001
BACKGROUND: More elderly patients affected by severe and chronic diseases are
treated in primary care. Reports on the use of prescription drugs by the general
elderly population are scarce, and more investigations are needed to optimize
pharmaceutical care for these patients. OBJECTIVE: To analyze prescription drug
use, diagnoses, and healthcare utilization among noninstitutionalized elderly
patie...
Relationships Between Beliefs about Medications and Nonadherence to Prescribed Chronic Medications
Annals of Pharmacotherapy - Tập 40 Số 10 - Trang 1737-1742 - 2006
Background: Medication beliefs of patients with a specific medical condition
have been associated with nonadherence to drugs used to treat that condition.
However, associations between medication beliefs and nonadherence of individuals
on chronic, multiple medications have not been studied. Objective: To
investigate associations between patients' medication beliefs and nonadherence
to chronic drug...
Inappropriate Prescribing and Health Outcomes in Elderly Veteran Outpatients
Annals of Pharmacotherapy - Tập 31 Số 5 - Trang 529-533 - 1997
OBJECTIVE: To determine the relationship of inappropriate prescribing in the
elderly to health outcomes. SETTING: General Medical Clinic of the Durham
Veterans Affairs Medical Center. PATIENTS: A total of 208 veterans more than 65
years old who were each taking five or more drugs and participated in a
pharmacist intervention trial. MEASUREMENTS: Prescribing appropriateness was
assessed by a clinic...
Relationship between Asthma Drug Therapy Patterns and Healthcare Utilization
Annals of Pharmacotherapy - Tập 36 Số 4 - Trang 557-564 - 2002
BACKGROUND AND OBJECTIVE: Asthma drug therapy problems contribute significantly
to preventable hospitalizations and increased healthcare use in asthmatics.
Since asthma patients often require >1 medication for control of symptoms,
concurrent asthma drug therapies may be important in predicting excessive
healthcare utilization. The purpose of this study was to link inappropriate
asthma drug therapy...
Including the Assessment of Nontraditional Factors in Pharmacy School Admissions
Annals of Pharmacotherapy - Tập 39 Số 4 - Trang 721-726 - 2005
OBJECTIVE: To review the relevant literature regarding the predictive ability of
cognitive measures (ie, Pharmacy College Admissions Test [PCAT] scores and
prepharmacy grade point average [GPA]) on both academic and clinical performance
and discuss the inclusion of nontraditional assessment during the admissions
process. DATA SOURCES: Articles were identified through searches of
International Phar...
Efficacy and Safety of Argatroban and Bivalirudin in Patients with Suspected Heparin-Induced Thrombocytopenia
Annals of Pharmacotherapy - Tập 49 Số 2 - Trang 178-184 - 2015
Background: Argatroban is the only commercially available Food and Drug
Administration (FDA)–approved anticoagulant for managing heparin-induced
thrombocytopenia (HIT). However, bivalirudin may be an attractive alternative.
Objective: To assess the efficacy and safety of argatroban and bivalirudin in
patients with suspected HIT. Methods: This single-center, retrospective analysis
included patients...
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