American Society for Microbiology

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Heterogeneity in Mitochondrial Morphology and Membrane Potential Is Independent of the Nuclear Division Cycle in Multinucleate Fungal Cells
American Society for Microbiology - Tập 11 Số 3 - Trang 353-367 - 2012
John Gerstenberger, Patricia Occhipinti, Amy S. Gladfelter
ABSTRACT In the multinucleate filamentous fungus Ashbya gossypii , nuclei divide asynchronously in a common cytoplasm. We hypothesize that the division cycle machinery has a limited zone of influence in the cytoplasm to promote nuclear autonomy. Mito...... hiện toàn bộ
Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis
American Society for Microbiology - Tập 9 Số 3 - Trang 352-359 - 2010
Clara M. Bien, Peter J. Espenshade
ABSTRACT Sterol regulatory element binding proteins (SREBPs) are membrane-bound transcription factors whose proteolytic activation is controlled by the cellular sterol concentration. Mammalian SREBPs are activated in cholesterol-depleted cells and serve to regulate cellular lipid homeostasis. Recent work demonstrates that SREBP is functionall...... hiện toàn bộ
Independent Metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae
American Society for Microbiology - Tập 4 Số 11 - Trang 1863-1871 - 2005
G A Keller, Amanda Bird, Dennis R. Winge
ABSTRACT Ace1 and Mac1 undergo reciprocal copper metalloregulation in yeast cells. Mac1 is functional as a transcriptional activator in copper-deficient cells, whereas Ace1 is a transcriptional activator in copper-replete cells. Cells undergoing a transition from copper-deficient to copper-sufficient conditions through a switch in the growth medium show a...... hiện toàn bộ
Saccharomyces cerevisiae Heat Shock Transcription Factor Regulates Cell Wall Remodeling in Response to Heat Shock
American Society for Microbiology - Tập 4 Số 6 - Trang 1050-1056 - 2005
Hiromi Imazu, Hiroshi Sakurai
ABSTRACT The heat shock transcription factor Hsf1 of the yeast Saccharomyces cerevisiae regulates expression of genes encoding heat shock proteins and a variety of other proteins as well. To better understand the cellular roles of Hsf1, we screened multicopy suppressor genes of a temperature-...... hiện toàn bộ
Role of Heat Shock Transcription Factor in Saccharomyces cerevisiae Oxidative Stress Response
American Society for Microbiology - Tập 6 Số 8 - Trang 1373-1379 - 2007
Ayako Yamamoto, Junko Ueda, Noritaka Yamamoto, Naoya Hashikawa, Hiroshi Sakurai
ABSTRACT The heat shock transcription factor Hsf1 of the yeast Saccharomyces cerevisiae regulates the transcription of a set of genes that contain heat shock elements (HSEs) in their promoters and function in diverse cellular processes, including protein folding. Here, we show that Hsf1 activ...... hiện toàn bộ
Regulation of Thermotolerance by Stress-Induced Transcription Factors in Saccharomyces cerevisiae
American Society for Microbiology - Tập 7 Số 5 - Trang 783-790 - 2008
Noritaka Yamamoto, Yuka Maeda, Aya Ikeda, Hiroshi Sakurai
ABSTRACT The heat shock transcription factor Hsf1 and the general stress transcription factors Msn2 and Msn4 (Msn2/4) are major regulators of the heat shock response in Saccharomyces cerevisiae . Here, we show that transcriptional activation of their target genes, including ... hiện toàn bộ
Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection by Cryptococcus neoformans
American Society for Microbiology - Tập 8 Số 11 - Trang 1803-1807 - 2009
Kiem Vu, Babette B. Weksler, Ignacio A. Romero, Angie Gelli
ABSTRACT Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for...
ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma brucei
American Society for Microbiology - Tập 5 Số 1 - Trang 45-53 - 2006
Silvia V. Brown, Paul Hosking, Jinlei Li, Noreen Williams
ABSTRACT The mitochondrion of Trypanosoma brucei bloodstream form maintains a membrane potential, although it lacks cytochromes and several Krebs cycle enzymes. At this stage, the ATP synthase is present at reduced, although significant, levels. To test whether the ATP synthase at this stage ...... hiện toàn bộ
Copper-Dependent Iron Assimilation Pathway in the Model Photosynthetic EukaryoteChlamydomonas reinhardtii
American Society for Microbiology - Tập 1 Số 5 - Trang 736-757 - 2002
Sharon La Fontaine, Jeanette Quinn, Stacie S. Nakamoto, M. Dudley Page, Vera Göhre, Jeffrey L. Moseley, Janette Kropat, Sabeeha Merchant
ABSTRACTThe unicellular green algaChlamydomonas reinhardtiiis a valuable model for studying metal metabolism in a photosynthetic background. A search of theChlamydomonasexpressed sequence tag database led to the identification of several components that form a copper-dependent iron assimilation pathway related t...... hiện toàn bộ
The Pre-mRNA Splicing Machinery of Trypanosomes: Complex or Simplified?
American Society for Microbiology - Tập 9 Số 8 - Trang 1159-1170 - 2010
Arthur Günzl
ABSTRACT Trypanosomatids are early-diverged, protistan parasites of which Trypanosoma brucei , Trypanosoma cruzi , and several species of ... hiện toàn bộ
Tổng số: 46   
  • 1
  • 2
  • 3
  • 4
  • 5