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Antimicrobial and Cytotoxic Activities of Neolignans from Magnolia officinalis
Wiley - Tập 1 Số 3 - Trang 530-537 - 2004
Wan‐Jr Syu, Chien‐Chang Shen, Jang‐Jih Lu, Gum‐Hee Lee, Changming Sun
AbstractIn the light of the steady increase of infections related to vancomycin‐resistant enterococci (VRE) and methicillin‐resistant Staphylococcus aureus (MRSA), the medicinal plant Magnolia officinalis was subjected to bioassay‐directed fractionation, which led to the isolation of the known neolignans piperit...... hiện toàn bộ
New Limonoids from the Seeds of a Krishna Mangrove, Xylocarpus granatum
Wiley - Tập 10 Số 4 - Trang 612-620 - 2013
Hongliang Chen, Jing Zhang, Min‐Yi Li, Tirumani Satyanandamurty, Jun Wu
AbstractTwo new mexicanolides, named granatumins H and I (1 and 2, resp.), and two phragmalins, named granatumins J and K (3 and 4, resp.), were isolated from the seeds of an Indian mangrove, Xylocarpus moluccensis, collected from the swamps of Kri...... hiện toàn bộ
Garcimultiflorone G, a Novel Benzoylphloroglucinol Derivative from Garcinia multiflora with Inhibitory Activity on Neutrophil Pro‐Inflammatory Responses
Wiley - Tập 11 Số 5 - Trang 819-824 - 2014
Chia‐Wei Ting, Tsong‐Long Hwang, Yu‐Chang Chen, Ming‐Jen Cheng, Ping‐Jyun Sung, Ming‐Hong Yen, Jih‐Jung Chen
AbstractA novel benzoylphloroglucinol derivative, garcimultiflorone G (1), was isolated from the fruits of Garcinia multiflora. The structure of 1 was determined through extensive 1D‐ and 2D‐NMR, and MS analyses. Garcimultiflorone G (1) showed inhibitory effects against ...... hiện toàn bộ
Heat Shock Factor 1 Inducers from the Bark of Eucommia ulmoides as Cytoprotective Agents
Wiley - Tập 10 Số 7 - Trang 1322-1327 - 2013
Joo‐Won Nam, Seoyoung Kim, Taesook Yoon, Yoo Jin Lee, Yun-Seo Kil, Yun‐Sil Lee, Eun Kyoung Seo
AbstractThe barks of Eucommia ulmoides (Eucommiae Cortex, Eucommiaceae) have been used as a traditional medicine in Korea, Japan, and China to treat hypertension, reinforce the muscles and bones, and recover the damaged liver and kidney functions. Among these traditional uses, to establish the recovery effects on the damaged organs on the...... hiện toàn bộ
Fungal Transformation and Schistosomicidal Effects of Pimaradienoic Acid
Wiley - Tập 9 Số 8 - Trang 1465-1474 - 2012
Thiago S. Porto, Ademar Alves da Silva Filho, Lizandra Guidi Magalhães, Raquel Alves dos Santos, Niege Araçari Jacometti Cardoso Furtado, Nilton Syogo Arakawa, Suraia Said, Dionéia Camilo Rodrigues de Oliveira, Luiz Elídio Gregório, Vanderlei Rodrigues, Rodrigo Cássio Sola Veneziani, Sérgio Ricardo Ambrósio
AbstractThe schistosomicidal effects of pimaradienoic acid (PA) and two derivatives, obtained by fungal transformation in the presence of Aspergillus ochraceus, were investigated. PA was the only compound with antischistosomal activity among the three diterpenes studied, with the ability to significantly reduce the viability of the parasi...... hiện toàn bộ
Antiprotozoal, Schistosomicidal, and Antimicrobial Activities of the Essential Oil from the Leaves of Baccharis dracunculifolia
Wiley - Tập 7 Số 4 - Trang 993-1001 - 2010
Natállia A. Parreira, Lizandra Guidi Magalhães, Danielle Barcellos Morais, Soraya C. Caixeta, João Paulo Barreto de Sousa, Jairo Kenupp Bastos, Wilson Roberto Cunha, Márcio Luís Andrade e Silva, N. P. Dhammika Nanayakkara, Vanderlei Rodrigues, Ademar Alves da Silva Filho
AbstractBaccharis dracunculifolia DC. (Asteraceae), popularly known as ‘alecrim do campo’, is a native plant from Brazil used in folk medicine as febrifuge, anti‐inflammatory, antiseptic, and to treat skin sores. Also, B. dracunculifolia is the most important plant source of the Brazil...... hiện toàn bộ
Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept
Wiley - Tập 6 Số 11 - Trang 2030-2049 - 2009
Andreas Reichel
AbstractDespite enormous efforts, achieving a safe and efficacious concentration profile in the brain remains one of the big challenges in central nervous system (CNS) drug discovery and development. Although there are multiple reasons, many failures are due to underestimating the complexity of the brain, also in terms of pharmacokinetics (PK).To t...... hiện toàn bộ
Phytochemical and Biological Studies of Chloranthus Medicinal Plants
Wiley - Tập 10 Số 10 - Trang 1754-1773 - 2013
Yong‐Jiang Xu
AbstractThe plants of genus Chloranthus have been investigated in many chemical and pharmacological laboratories due to their complex secondary metabolites and diverse bioactivities. The aim of this review is to provide an up‐to‐date overview on the chemistry and bioactivity of the compounds isolated, mainly sesquiterpenoids and diterpeno...
Hydrophobicity of Peptides Containing D‐Amino Acids
Wiley - Tập 7 Số 6 - Trang 1670-1679 - 2010
Toratane Munegumi
AbstractSeveral types of L‐amino acid residues (Ser, Asp) in proteins are sometimes converted to D‐amino acid residues by posttranslational isomerization. This phenomenon leads to an increase in hydrophobicity and results in their deposition from aqueous media. This research involves the hydrophobicity of oligopeptides containi...... hiện toàn bộ
Chemical Composition, Anti‐Microbial, and Cytotoxic Activities of Essential Oil From Magnolia bidoupensis Q. N. Vu Leaves, an Endemic Species to the Central Highlands of Vietnam
Wiley -
Nguyễn Văn Ngọc, Nhi Tran, Hoàng Thị Bình
AbstractAn analysis was conducted on the essential oil extracted from the leaves of Magnolia bidoupensis utilizing GC‐MS, revealing thirty‐three constituents that account for 98.9 % of the essential oil. The main components included pogostol (22.4 %), δ‐selinene (16.2 %), and α‐amorphe...... hiện toàn bộ
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