Chemical Composition, Anti‐Microbial, and Cytotoxic Activities of Essential Oil From Magnolia bidoupensis Q. N. Vu Leaves, an Endemic Species to the Central Highlands of Vietnam

Wiley
Nguyễn Văn Ngọc1, Nhi Tran1, Hoàng Thị Bình1
1University of DaLat Biology 01 Phu Dong Thien Vuong 67000 Dalat VIET NAM

Tóm tắt

AbstractAn analysis was conducted on the essential oil extracted from the leaves of Magnolia bidoupensis utilizing GC‐MS, revealing thirty‐three constituents that account for 98.9 % of the essential oil. The main components included pogostol (22.4 %), δ‐selinene (16.2 %), and α‐amorphene (14.7 %). Bioassays were then performed to evaluate the oil's biological activity. The essential oil exhibited antimicrobial activity against all tested microorganisms (six bacterial strains and one fungal strain) using the minimum inhibitory concentration (MIC) method. Additional cytotoxicity tests were conducted on KB, HepG2, MCF‐7, and A549 cancer cell lines using the MTT method. The essential oil exhibited strong cytotoxic effects on all four cell lines, with IC50 values ranging from 1.37±0.05 μg/mL (KB) to 2.40±0.06 μg/mL (A549).

Từ khóa


Tài liệu tham khảo

M. Rivers E. Beech L. Murphy S. Oldfield The Red List of Magnoliaceae: revised and extended Richmond Surrey UK: Botanic Gardens Conservation International (BGCI) 2016.

Yahaya A. A. H., 2022, Riv. Ital. Sostanze Grasse, 99, 249

10.1111/jse.12588

10.3390/f13050802

10.3390/molecules25061359

10.25135/rnp.174.20.02.1541

10.1002/cbdv.202000750

Fu C., 2024, Bioenergy, 18, 377

Olazaran-Santibañez F. E., 2024, J. Entomol. Sci., 59, 193

Schühly W., 2008, Nat. Prod. Commun., 3

Sowndhararajan K., 2016, J. Appl. Pharm. Sci., 6, 146, 10.7324/JAPS.2016.60420

Lee J. Y., 2020, J. Life Sci., 30, 278

Shunhua J. I. A. N., 2022, China Food Additives, 33, 165

Trinh N. B., 2023, Biochem. Syst. Ecol., 109, 10.1016/j.bse.2023.104666

10.5650/jos.ess21241

Zhang J. W., 2024, Chem. Biodivers., 21, 10.1002/cbdv.202300935

Pham H. H., 2003, An Illustrated Flora of Vietnam, 230

Vu Q. N., 2011, Ann. Bot. Fenn., 48, 525, 10.5735/085.048.0616

10.1111/njb.00536

10.1111/njb.00540

Ha C. T., 2019, Nat. Prod. Commun., 14

Ha C. T. T., 2020, Acad. J. Biol., 42, 41

Ha C. T. T., 2020, Acad. J. Biol., 42, 135

Chu T. T. H., 2020, Am. J. Essen. Oils Nat. Prod., 8, 13

Ha C. T., 2021, Rec. Nat. Prod., 15, 207, 10.25135/rnp.212.20.10.1842

10.25135/rnp.174.20.02.1541

Ha C. T., 2022, Rec. Nat. Prod., 16, 503

Ha C. T., 2022, Acad. J. Biol., 44, 11

L. D. Ngoc Anh N. H. Dang B. V. Huong P. Arpino L. D. CuL. D. N. T. Kim Thanh In XXXI International Horticultural Congress (IHC2022): International Symposium on Medicinal and Aromatic Plants: Domestication 2022 1358 19–26.

10.1002/jssc.200900378

R. P. Adams Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry Allured Publ. Corp.: Carol Stream Illinois 2017.

P. J. Linstrom W. G. Mallard NIST Chemistry WebBook NIST Standard Reference Database Number 69 National Institute of Standards and Technology Gaithersburg MD 20899 2022.

10.33448/rsd-v10i2.12040

Da Silva J. K. R., 2017, Nat. Prod. Commun., 12, 131

Anh C., 2020, Exp.Ther. Med., 19, 2008

10.1080/14786419.2017.1303699

10.1111/j.1476-5381.2010.01127.x

Cos P., 2005, Bioassay for Antibacterial and Antifungal Activities”; Laboratory for Microbiology, 1

10.1016/0022-1759(83)90303-4

Thông tin
Thông tin xuất bản

Wiley

Thông tin tác giả