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Coating of intravascular balloon with paclitaxel prevents constrictive remodeling of the dilated porcine femoral artery due to inhibition of intimal and media fibrosis
Springer Science and Business Media LLC - Tập 27 - Trang 1-15 - 2016
Noemi Pavo, Eslam Samaha, Inna Sabdyusheva, Rembert Pogge von Strandmann, Stefanie Stahnke, Christian A. Plass, Katrin Zlabinger, Dominika Lukovic, Zoltan Jambrik, Imre J. Pavo, Jutta Bergler-Klein, William A. Gray, Gerald Maurer, Mariann Gyöngyösi
Here we investigated how a coating of intravascular balloon with paclitaxel (drug-coated balloon; DCB, Freeway™) impacted porcine peripheral artery vascular function and remodeling. Domestic swine (n = 54) underwent percutaneous overstretch balloon dilation of femoral and iliac arteries, controlled by angiography and optical coherence tomography (OCT). Paclitaxel tissue uptake was measured at 1 h ...... hiện toàn bộ
X-ray diffraction characterization of dental gold alloy-ceramic interfaces
Springer Science and Business Media LLC - Tập 12 - Trang 215-223 - 2001
Z. Cai, I. Watanabe, J. C. Mitchell, W. A. Brantley, T. Okabe
X-ray diffraction (XRD) was employed to study dental alloy-ceramic interfaces. A Au-Pd-In alloy, which requires oxidation before porcelain firing, and a Au-Pt-Pd-In alloy, which does not require oxidation before porcelain firing, were selected in this study. Alloy specimens were centrifugally cast. Specimen surfaces were metallographically polished through 0.05 μm Al2,O3} slurries. A thin layer (<...... hiện toàn bộ
Blood response to plasticized poly(vinyl chloride): Dependence of fibrinogen adsorption on plasticizer selection and surface plasticizer level
Springer Science and Business Media LLC - Tập 14 - Trang 905-912 - 2003
X. B. Zhao, J. M. Courtney
The high level of plasticizer in plasticized poly(vinyl chloride) (PVC) ensures that plasticizer selection has an important influence on the suitability of PVC to function in blood-contacting applications. In this study, three types of plasticized PVC in sheet form, with di-(2-ethylhexyl)phthalate (DEHP), tri-(2-ethylhexyl)trimellitate (TEHTM) and n-butyryltri-n-hexyl citrate (BTHC) as plasticizer...... hiện toàn bộ
Một phương pháp đơn giản để kiểm soát sự bám dính của tế bào trên các mô hình nuôi cấy tế bào trong ống nghiệm được phát triển từ sinh học thông qua liên kết RGD được điều chế bằng UV Dịch bởi AI
Springer Science and Business Media LLC - - 2020
Ana María Porras Hernández, Hannah Pohlit, Frida Sjögren, Liyang Shi, Dmitri Ossipov, Maria Antfolk, Maria Tenje
Tóm tắtTrong nghiên cứu này, chúng tôi trình bày một phương pháp chế tạo hydrogel axit hyaluronic (HA) với các tính chất bám dính tế bào được kiểm soát không gian dựa trên việc bắt chéo polymer hóa bằng ánh sáng và chức năng hóa. Cách tiếp cận này sử dụng cùng một con đường phản ứng cho cả hai bước, có nghĩa là nó thân thiện với người dùng và cho phép thích ứng ở b...... hiện toàn bộ
Directional and temporal variation of the mechanical properties of robocast scaffold during resorption
Springer Science and Business Media LLC - Tập 26 - Trang 1-8 - 2015
J. Waygood, G. E. Murch, T. Fiedler
This paper addresses the mechanical behavior of robocast PCL-Bioglass® scaffolds. These structures can be used as 3rd generation implants in tissue engineering to support the regrowth of damaged tissue, in particular bone. After successful tissue regeneration the scaffolds slowly dissolve leaving no foreign material permanently inside the body. However, to avoid mechanical separation from surround...... hiện toàn bộ
Effect of processing parameters on the microstructure and mechanical behavior of silica-calcium phosphate nanocomposite
Springer Science and Business Media LLC - Tập 21 - Trang 2087-2094 - 2010
Xueran Liu, Ahmed EI-Ghannam
Silica-calcium phosphate nanocomposite (SCPC) is a bioactive ceramic characterized by superior bone regenerative capacity and resorbability when compared to traditional bioactive ceramics. The aim of the present study is to evaluate the effect of processing parameters on the microstructure and mechanical properties of SCPC. Cylinders were prepared by pressing the ceramic powder at 200, 300 or 400 ...... hiện toàn bộ
Surface tailoring of poly(ethylene terephthalate) via ligand-tethered comb-like PEG to enhance endothelialization
Springer Science and Business Media LLC - Tập 19 - Trang 291-299 - 2007
Xiaolin Li, Jian Ji, Ming Pu, Xiaoli Wang, Jiacong Shen
The comb-like PEG (CPEG) end-tethered with l-lysine was explored to surface modification of PET to enhance endothelialization. The hydroxyl end groups of CPEG were oxygenated into aldehyde groups. The CPEG-CHO was grafted onto the aminolysized PET. The l-lysine was then end-tethered onto surface via the residual aldehyde groups. The surface modification was confirmed by ATR-FTIR, contact angle and...... hiện toàn bộ
Primary osteoblast cell response to sol-gel derived bioactive glass foams
Springer Science and Business Media LLC - Tập 16 - Trang 851-856 - 2005
P. Valerio, M. H. R. Guimaráes, M. M. Pereira, M. F. Leite, A. M. Goes
Bioactive glass macroporous structures were developed in this work to be used as scaffolds for bone tissue engineering applications. A sol-gel route was used to obtain glass foams with the introduction of a gas phase in the solution and by vigorous agitation of the sol-gel solution that contains a foam agent. Stable and homogeneous foams were formed near the gelation point, which were than dried a...... hiện toàn bộ
Development of graded hydroxyapatite/CaCO3 composite structures for bone ingrowth
Springer Science and Business Media LLC - Tập 18 - Trang 1817-1824 - 2007
F. Heilmann, O. C. Standard, F. A. Müller, M. Hoffman
Ceramic composites composed of constituents with different bone cell reactions present an interesting consideration for a new bone replacement material. The first component of the composite used in this study, hydroxyapatite, is known to be replaced by natural tissue significantly slower than the second, calcium carbonate, which has limited structural stability. A graded hydroxyapatite/calcium car...... hiện toàn bộ
The effect of temperature and shear rate on platelet aggregation
Springer Science and Business Media LLC - Tập 8 - Trang 887-890 - 1997
A. P SHORTLAND, N. P RHODES, A RATTRAY, R. A BLACK, D. F WILLIAMS
Samples of whole blood were obtained from male volunteers and exposed to combinations of shear rates and temperatures representative of cardiopulmonary bypass (CPB) in a modified computer-controlled concentric cylinder rotational viscometer for a period of 100 s. Blood sampled from the chamber was fixed in paraformaldehyde, stained with CD41 and analysed by flow cytometry. Only platelet-positive p...... hiện toàn bộ
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