Comparison of cellular toxicity caused by ambient ultrafine particles and engineered metal oxide nanoparticlesSpringer Science and Business Media LLC - Tập 12 - Trang 1-12 - 2015
Senlin Lu, Wenchao Zhang, Rui Zhang, Pinwei Liu, Qiangxiang Wang, Yu Shang, Minghong Wu, Ken Donaldson, Qingyue Wang
The development of nanotechnology has spurred concerns about the health effects of exposure to nanoparticles (NPs) and ultrafine particles (UFPs). Toxicological data on NPs and UFPs may provide evidence to support the development of regulations to reduce the risk of particle exposure. We tried to provide fundamental data to determine differences in cytotoxicity induced by ambient UFPs and engineer...... hiện toàn bộ
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workersSpringer Science and Business Media LLC - Tập 18 - Trang 1-16 - 2021
Antonio León-Jiménez, José M. Mánuel, Marcial García-Rojo, Marina G. Pintado-Herrera, José Antonio López-López, Antonio Hidalgo-Molina, Rafael García, Pedro Muriel-Cueto, Nieves Maira-González, Daniel Del Castillo-Otero, Francisco M. Morales
Engineered stone silicosis is an emerging disease in many countries worldwide produced by the inhalation of respirable dust of engineered stone. This silicosis has a high incidence among young workers, with a short latency period and greater aggressiveness than silicosis caused by natural materials. Although the silica content is very high and this is the key factor, it has been postulated that ot...... hiện toàn bộ
Intracellular imaging of nanoparticles: Is it an elemental mistake to believe what you see?Springer Science and Business Media LLC - Tập 7 - Trang 1-6 - 2010
Christina Brandenberger, Martin JD Clift, Dimitri Vanhecke, Christian Mühlfeld, Vicki Stone, Peter Gehr, Barbara Rothen-Rutishauser
In order to understand how nanoparticles (NPs <100 nm) interact with cellular systems, potentially causing adverse effects, it is important to be able to detect and localize them within cells. Due to the small size of NPs, transmission electron microscopy (TEM) is an appropriate technique to use for visualizing NPs inside cells, since light microscopy fails to resolve them at a single particle lev...... hiện toàn bộ
Hepatotoxicity and the role of the gut-liver axis in rats after oral administration of titanium dioxide nanoparticlesSpringer Science and Business Media LLC - Tập 16 - Trang 1-17 - 2019
Zhangjian Chen, Di Zhou, Shuo Han, Shupei Zhou, Guang Jia
Due to its excellent physicochemical properties and wide applications in consumer goods, titanium dioxide nanoparticles (TiO2 NPs) have been increasingly exposed to the environment and the public. However, the health effects of oral exposure of TiO2 NPs are still controversial. This study aimed to illustrate the hepatotoxicity induced by TiO2 NPs and the underlying mechanisms. Rats were administer...... hiện toàn bộ
Effects of particulate matter on inflammatory markers in the general adult populationSpringer Science and Business Media LLC - Tập 9 - Trang 1-9 - 2012
Dai-Hua Tsai, Nadia Amyai, Pedro Marques-Vidal, Jia-Lin Wang, Michael Riediker, Vincent Mooser, Fred Paccaud, Gerard Waeber, Peter Vollenweider, Murielle Bochud
Particulate air pollution is associated with increased risk of cardiovascular disease and stroke. Although the precise mechanisms underlying this association are still unclear, the induction of systemic inflammation following particle inhalation represents a plausible mechanistic pathway. We used baseline data from the CoLaus Study including 6183 adult participants residing in Lausanne, Switzerlan...... hiện toàn bộ
Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterizationSpringer Science and Business Media LLC - Tập 15 - Trang 1-9 - 2018
Siqi Zhang, Susanne Breitner, Wayne E Cascio, Robert B Devlin, Lucas M Neas, David Diaz-Sanchez, William E Kraus, Joel Schwartz, Elizabeth R Hauser, Annette Peters, Alexandra Schneider
Air pollution-induced changes in cardiac electrophysiological properties could be a pathway linking air pollution and cardiovascular events. The evidence of air pollution effects on the cardiac conduction system is incomplete yet. We investigated short-term effects of particulate matter ≤ 2.5 μm in aerodynamic diameter (PM2.5) and ozone (O3) on cardiac electrical impulse propagation and repolariza...... hiện toàn bộ
Human exposure to diesel exhaust induces CYP1A1 expression and AhR activation without a coordinated antioxidant responseSpringer Science and Business Media LLC - Tập 20 - Trang 1-13 - 2023
M. Friberg, A. F. Behndig, J. A. Bosson, Ala Muala, S. Barath, R. Dove, D. Glencross, F. J. Kelly, A. Blomberg, I. S. Mudway, T. Sandström, J. Pourazar
Diesel exhaust (DE) induces neutrophilia and lymphocytosis in experimentally exposed humans. These responses occur in parallel to nuclear migration of NF-κB and c-Jun, activation of mitogen activated protein kinases and increased production of inflammatory mediators. There remains uncertainty regarding the impact of DE on endogenous antioxidant and xenobiotic defences, mediated by nuclear factor e...... hiện toàn bộ
Concentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteersSpringer Science and Business Media LLC - Tập 15 - Trang 1-11 - 2018
Christian Monsé, Olaf Hagemeyer, Monika Raulf, Birger Jettkant, Vera van Kampen, Benjamin Kendzia, Vitali Gering, Günther Kappert, Tobias Weiss, Nadin Ulrich, Eike-Maximilian Marek, Jürgen Bünger, Thomas Brüning, Rolf Merget
Inhalation of high concentrations of zinc oxide particles (ZnO) may cause metal fume fever. In an earlier human inhalation study, no effects were observed after exposure to ZnO concentrations of 0.5 mg/m3. Further data from experimental studies with pure ZnO in the concentration range between 0.5 and 2.5 mg/m3 are not available. It was the aim of this experimental study to establish the concentrat...... hiện toàn bộ
Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissionsSpringer Science and Business Media LLC - Tập 1 - Trang 1-10 - 2004
Michael Riediker, Robert B Devlin, Thomas R Griggs, Margaret C Herbst, Philip A Bromberg, Ronald W Williams, Wayne E Cascio
Exposure to fine particulate matter air pollutants (PM2.5) affects heart rate variability parameters, and levels of serum proteins associated with inflammation, hemostasis and thrombosis. This study investigated sources potentially responsible for cardiovascular and hematological effects in highway patrol troopers. Nine healthy young non-smoking male troopers working from 3 PM to midnight were stu...... hiện toàn bộ