Scandinavian Journal of Immunology
SCIE-ISI SCOPUS (1972-2025)
0300-9475
1365-3083
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
ImmunologyMedicine (miscellaneous)
Các bài báo tiêu biểu
Mesenchymal Stem Cells Inhibit and Stimulate Mixed Lymphocyte Cultures and Mitogenic Responses Independently of the Major Histocompatibility Complex
Tập 57 Số 1 - Trang 11-20 - 2003
AbstractWe aimed to study the effects of mesenchymal stem cells (MSCs) on
alloreactivity and effects of T‐cell activation on human peripheral blood
lymphocytes (PBLs) in vitro. MSCs were expanded from the bone marrow of healthy
subjects. MSCs isolated from second to third passage were positive for CD166,
CD105, CD44, CD29, SH‐3 and SH‐4, but negative for CD34 and CD45. MSCs cultured
in osteogenic,...
The Involution of the Ageing Human Thymic Epithelium is Independent of Puberty
Tập 22 Số 5 - Trang 563-575 - 1985
One hundred and thiriy‐six thymuses completely removed; il autopsy from persons
suffering a sudden death were examined by stereological and morphomelrical
meihods. Adding biopsy material from immunologically healthy cardiac patients we
obtained relative volumes from 204 persons ranging in age from 1 month to 107
years. The size of the human thymus remains unchanged during ageing under normal
physi...
Utility of the Housekeeping Genes 18S rRNA, β‐Actin and Glyceraldehyde‐3‐Phosphate‐Dehydrogenase for Normalization in Real‐Time Quantitative Reverse Transcriptase‐Polymerase Chain Reaction Analysis of Gene Expression in Human T Lymphocytes
Tập 59 Số 6 - Trang 566-573 - 2004
AbstractThe accuracy of 18S rRNA, β‐actin mRNA and glyceraldehyde‐3‐phosphate
dehydrogenase (GAPDH) mRNA as indicators of cell number when used for
normalization in gene expression analysis of T lymphocytes at different
activation stages was investigated. Quantitative real‐time reverse
transcriptase‐polymerase chain reaction was used to determine the expression
level of 18S rRNA, β‐actin mRNA, GAP...
Autoantibodies to the Nuclear Sp100 Protein in Primary Biliary Cirrhosis and Associated Diseases: Epitope Specificity and Immunoglobulin Class Distribution
Tập 36 Số 4 - Trang 555-564 - 1992
Sp100, a protein with a dot‐like intranuclear localization in immunofluorescence
microscopy, is a major target for patient autoantibodies in primary biliary
cirrhosis (PBC) and occasionally in rheumatic disorders. The human Sp 100 cDNA
has recently been cloned, and the deduced amino acid sequence was found to
contain sequence similarities with an MHC class I domain and several transacting
regulato...
Mesenchymal Stem Cells Inhibit the Expression of CD25 (Interleukin‐2 Receptor) and CD38 on Phytohaemagglutinin‐Activated Lymphocytes
Tập 60 Số 3 - Trang 307-315 - 2004
AbstractMesenchymal stem cells (MSC) are immunomodulatory and inhibit lymphocyte
proliferation. We studied surface expression of lymphocyte activation markers
and secreted cytokines, when lymphocytes were activated in the presence of MSC.
MSC suppressed the proliferation of phytohaemagglutinin (PHA)‐stimulated CD3+,
CD4+ and CD8+ lymphocytes. MSC significantly reduced the expression of
activation ...
Endotoxin‐Stimulated Human Monocyte Secretion of Interleukin 1, Tumour Necrosis Factor Alpha, and Prostaglandin E2 Shows Stable Interindividual Differences
Tập 27 Số 6 - Trang 705-716 - 1988
The secretions of interleukin 1 (IL‐1), tumour necrosis factor α (TNF), and
prostaglandin E2 (PGE2) of low‐dose E. coli lipopolysaccharide (LPSJ‐stimulated
human monocytes (Mø) were investigated in an endotoxin (ET)‐free milieu (<1.6 pg
LPS/ml). Human Mø cultures from nine healthy men were stimulated with 0,
12.5–500, and 250,000 pg LPS/ml as measured by a very sensitive Limulus test.
The IL‐1 act...
T Lymphocytes in Collagen II‐Induced Arthritis in Mice
Tập 22 Số 3 - Trang 295-306 - 1985
Collagen type II‐spedfic long‐term cultured T helper cells, derived from the
DBA/1 mouse, have been established and characterized. Clones from these T‐cell
lines could he shown to recognize either species‐specific or species‐nonspecific
determinants on the collagen type II molecule, including determinants on
autologous mouse collagen. Induction of arthritis via transfer to both
irradiated and norm...
An Emerging Role for Galectins in Tuning the Immune Response: Lessons from Experimental Models of Inflammatory Disease, Autoimmunity and Cancer
Tập 66 Số 2-3 - Trang 143-158 - 2007
AbstractInflammation is a critical process for eliminating pathogens, but can
lead to serious deleterious effects if left unchecked. Identifying the
endogenous factors that control immune tolerance and inflammation is a key goal
in the field of immunology. Galectins, a family of endogenous lectins with
affinity for β‐galactoside‐containing oligosaccharides, are expressed by several
cells of the im...
The Antigens of Mycobacterium bovis, Strain BCG, Studied by Crossed Immunoelectrophoresis: a Reference System
Tập 12 Số 3 - Trang 249-263 - 1980
A reference system for the soluble antigen of Mycobacterium bovis, strain BCG is
described. The system is based on crossed immunoelectrophoresis with
intermediate gel. A Commercially available immunoglobulin preparation made from
rabbit anti‐BCG hyperimmune serum was used as reference antibodies, while a
concentrated BCG culture filtrate was used as reference antigen. The pattern
obtained was high...
Down‐Regulation of Anti‐CD3 Antibody‐Induced IL‐4 Production by Bovine Caseins Hydrolysed with Lactobacillus GG‐Derived Enzymes
Tập 43 Số 6 - Trang 687-689 - 1996
A prerequisite for systemic hyporesponsiveness to dietary antigens is their
processing in the gut. This study investigated whether bovine caseins degraded
by enzymes of an intestinal bacterial strain, Lactobacillus GG (ATCC 53103),
could regulate the cytokine production by anti‐CD3 antibody‐induced peripheral
blood mononuclear cells of 14 atopic patients, aged 5–29 (mean, 16) months.
Purified case...