Preferential Expression of VH5 and VH6 Immunoglobulin Genes in Early Human B‐Cell OntogenyScandinavian Journal of Immunology - Tập 30 Số 4 - Trang 493-497 - 1989
Anne‐Marie Cuisinier, V. Guigou, L. Boubli, M. Fougereau, Cécile Tonnelle
Analysis of Ig transcripts by dot blot hybridization revealed that VH5 and VH6 RNA first occurred during the 7th week of gestation in human fetal liver. At the same time, a Cλ or Cλ‐like chain was also expressed, in the absence of detectable K chains. In adult B cells, VH3 appears to be the dominant f...... hiện toàn bộ
Spiegelmer Inhibition of MCP‐1/CCR2 – Potential as an Adjunct Immunosuppressive Therapy in TransplantationScandinavian Journal of Immunology - Tập 82 Số 2 - Trang 102-109 - 2015
Aivars Kalnins, Michael Thomas, M. Andrassy, Sebastian Müller, Alexandra Wagner, Sebastian Pratschke, Markus Rentsch, JP Klußmann, Teresa Kauke, Martin K. Angele, Alexandr V. Bazhin, Michael Fischereder, Jens Werner, Markus Guba, Joachim Andrassy
AbstractThe rejection process remains the key unsolved issue after transplantation of disparate tissue. The CC chemokine monocyte chemoattractant protein‐1 (MCP‐1/CCL2) has been reported to be involved in the process of alloimmune interaction. Spiegelmers are l‐oligonucleotides that can be designed to bind to pharmacologically relevant target mol...... hiện toàn bộ
Sharing of Ia Antigens between SpeciesScandinavian Journal of Immunology - Tập 10 Số 5 - Trang 403-413 - 1979
Joan K. Lunney, Dean Mann, David H. Sachs
Certain mouse alloantisera have been found to detect immunologic cross‐reactions between human and murine Ia antigens. Almost every anti‐Iaa, ‐Iak and ‐Iad serum tested exhibited such cross‐reactions. Sera prepared against the products of limited segments of the mouse I region and tested on human B cells revealed that anti‐I‐E/...... hiện toàn bộ
Experimental Infections of Rana esculenta with Aeromonas hydrophila: A Molecular Mechanism for the Control of the Normal FloraScandinavian Journal of Immunology - Tập 48 Số 4 - Trang 357-363 - 1998
Simmaco, Maria Luisa Mangoni, Boman, Barra
Frogs can be useful models for studying the mechanisms that may regulate their natural microbial flora. Their skin glands produce a secretion containing 20–30 different peptides, some antimicrobial some neurotrophic. As they often live in soil or silt that is rich in microbes, they can be expected to be able to prevent or eliminate infections in very short peroids of time. The bacterium ... hiện toàn bộ
Two Nuclear Dot‐Associated Proteins, PML and SplOO, are Often Co‐Autoimmunogenic in Patients with Primary Biliary CirrhosisScandinavian Journal of Immunology - Tập 42 Số 2 - Trang 257-268 - 1995
Thomas Sternsdorf, H H Guldner, Carin Szostecki, Thilo Grötzinger, Hans Will
The nucleoproteins Sp100 and PML, the first an autoantigen predominant in patients with primary biliary cirrhosis (PBC) and the second a transformation and cell growth suppressing protein aberrantly expressed in promyelocytic leukaemia ceils, were recently shown to colocalize in dot‐like nuclear domains. Here we analysed whether PML, like Sp100, is also an autoantigen in patients with PBC ...... hiện toàn bộ
Immunoassay for Transthyretin Variants associated with Amyloid NeuropathyScandinavian Journal of Immunology - Tập 38 Số 2 - Trang 177-182 - 1993
Paulo Costa, A. Teixeira, Maria João Saraiva
An anti‐transthyretin (TTR) mouse monoclonal antibody (88.6.FD6)of IgG1 subclass, obtained using as immunogen TTR from the serum of a patient with familial amyloidotic polyneuropathy, was found to bind to sera from carriers of several amyloidogenic TTR variants associated with peripheral neuropathy, but not to normal sera or sera from carriers of non‐pathogenic or cardiomyopathic variants,...... hiện toàn bộ
Role of T Lymphocytes in Experimental Staphylococcus aureus ArthritisScandinavian Journal of Immunology - Tập 39 Số 4 - Trang 403-408 - 1994
Arturo Abdelnour, T Bremell, Rikard Holmdahl, Andrzej Tarkowski
Using a recently developed murine model of haematogenously induced Staphylococcus aureus, the authors have characterized the phenotypes and functional properties of inflammatory cells present in the synovium of arthritic mice. The results show that large numbers of granulocytes and macrophages were observed in the inflamed synovia within 24 h of inoculation of S....... hiện toàn bộ
Induction of Host Protective Th1 Immune Response by Chemokines in Leishmania donovani‐infected BALB/c MiceScandinavian Journal of Immunology - Tập 66 Số 6 - Trang 671-683 - 2007
Ranadhir Dey, Nivedita Majumder, S. Majumdar, Surajit Bhattacharjee, Sayantan Banerjee, Syamal Roy, Shamik Majumdar
AbstractThe resolution from leishmanial infection is dependent on the coordinated interactions between the components of the cell mediated immune system and the activation of T‐cell population into appropriate cytokine production and the activation of macrophages. Earlier reports established that C‐C chemokines particularly macrophage inflammatory protein (MIP)‐1α ...... hiện toàn bộ