Psychobiology
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Neural activity differs between explicit and implicit learning of artificial grammar strings: An fMRI study
Tập 28 Số 3 - Trang 283-292 - 2000
Functional magnetic resonance imaging was used to investigate the neural areas underlying retrieval of implicit and explicit knowledge about letter strings. Participants studied strings formed according to an artificial grammar, then performed implicit-learning-based judgments (judging the grammatical status of the string) or explicit-learning-based judgments (recognition) on novel grammatical str......
Effects of des-glycinamide9-[arginine8] vasopressin upon spatial memory in the hole-board search task
Tập 23 Số 1 - Trang 45-51 - 1995
The hole-board search task (HBST), a spatial learning test, was used to measure errors, working memory, reference memory, sequence, and response bias. Various dosages of desglycinamide9-[arginine8] vasopressin (DGAVP; 0.17, 0.5, 1, 3, and 10 µg) were administered in double blind experiments 1 h prior to six training sessions in the HBST. Body weight loss was a covariant in a repeated measures mult......
Persistence of sham feeding after intragastric meals in the rat: Concentration-intake relations
Tập 21 Số 1 - Trang 55-59 - 1993
In rats sham fed through esophageal fistulas, responsiveness to sucrose over a range of concentrations was assessed under two conditions: immediately following a large intragastric (IG) preload of liquid diet, and after 10 h of deprivation with no preload. The preload had no reliable effect on sucrose sham feeding at any sucrose concentration. Therefore, the insensitivity of sham feeding to IG loa......
Pathoclysis in aging human cerebral cortex: Evidence from in vivo MRI morphometry
Tập 21 Số 2 - Trang 151-160 - 1993
Age-related differences in the cross-sectional area and volume of selected cortical regions were examined by using in vivo magnetic resonance morphometry. In two samples—healthy volunteers and patients with negative radiological findings—similar patterns of cortical aging emerged. The size of sampled regions of association cortices correlated negatively with age, whereas no significant correlation......
Drug-induced changes in responding are dependent on baseline stimulus-reinforcer contingencies
Tập 27 Số 1 - Trang 95-104 - 1999
The disruptive effect of four drugs was examined using a multiple-schedule procedure that allowed the assessment of behavioral resistance to change. With rats as subjects, responding in one component was maintained on a variable-interval (VI) 30-sec schedule, and responding in the other components was maintained using a VI 30-sec schedule that operated concurrently with a variable-time 30-sec sche......
Limited and extensive cuing inversely control spatial learning performance in fornix-damaged and nonlesioned rats
Tập 19 Số 4 - Trang 323-331 - 1991
This work examines the influence of contextual manipulations on radial maze performance in fornix-damaged and control rats by presenting the task in two differentiated contexts—limited versus extensive cuing—that were successively inverted. With limited cuing, fornix-damaged rats perform worse than controls. Extensive cuing counteracts performance deficits in lesioned rats but impairs performance ......
Visual object representation: An introduction
Tập 26 Số 4 - Trang 281-308 - 1998
What are the computational, behavioral, and neural mechanisms that give rise to object perception? In this review, I present a cognitive neuroscience overview of the literature on object representation. Marr’s (1982) framework for studying complex tasks is used as a guide for the review. This framework involves analyzing a problem on three levels: (1) the computational theory, which asks what is c......