Psychobiology
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Các bài báo tiêu biểu
Limited and extensive cuing inversely control spatial learning performance in fornix-damaged and nonlesioned rats
Tập 19 Số 4 - Trang 323-331 - 1991
This work examines the influence of contextual manipulations on radial maze
performance in fornix-damaged and control rats by presenting the task in two
differentiated contexts—limited versus extensive cuing—that were successively
inverted. With limited cuing, fornix-damaged rats perform worse than controls.
Extensive cuing counteracts performance deficits in lesioned rats but impairs
performance ...
Effects of des-glycinamide9-[arginine8] vasopressin upon spatial memory in the hole-board search task
Tập 23 Số 1 - Trang 45-51 - 1995
The hole-board search task (HBST), a spatial learning test, was used to measure
errors, working memory, reference memory, sequence, and response bias. Various
dosages of desglycinamide9-[arginine8] vasopressin (DGAVP; 0.17, 0.5, 1, 3, and
10 µg) were administered in double blind experiments 1 h prior to six training
sessions in the HBST. Body weight loss was a covariant in a repeated measures
mult...
Visual object representation: An introduction
Tập 26 Số 4 - Trang 281-308 - 1998
What are the computational, behavioral, and neural mechanisms that give rise to
object perception? In this review, I present a cognitive neuroscience overview
of the literature on object representation. Marr’s (1982) framework for studying
complex tasks is used as a guide for the review. This framework involves
analyzing a problem on three levels: (1) the computational theory, which asks
what is c...
Arginine vasopressin facilitates reversal and impairs retention of a brightness discrimination in albino rats
Tập 15 Số 4 - Trang 329-335 - 1987
One microgram of arginine vasopressin (AVP) or a placebo was administered to
male albino rats. Performance on the original learning, reversal learning, and
retention of a black-white visual discrimination was assessed by means of both
trials and errors to criterion. In Experiment 1, the rats were given AVP after
original learning trials and prior to retention trials. In Experiment 2, the
rats were...
Pathoclysis in aging human cerebral cortex: Evidence from in vivo MRI morphometry
Tập 21 Số 2 - Trang 151-160 - 1993
Age-related differences in the cross-sectional area and volume of selected
cortical regions were examined by using in vivo magnetic resonance morphometry.
In two samples—healthy volunteers and patients with negative radiological
findings—similar patterns of cortical aging emerged. The size of sampled regions
of association cortices correlated negatively with age, whereas no significant
correlation...
Neural activity differs between explicit and implicit learning of artificial grammar strings: An fMRI study
Tập 28 Số 3 - Trang 283-292 - 2000
Functional magnetic resonance imaging was used to investigate the neural areas
underlying retrieval of implicit and explicit knowledge about letter strings.
Participants studied strings formed according to an artificial grammar, then
performed implicit-learning-based judgments (judging the grammatical status of
the string) or explicit-learning-based judgments (recognition) on novel
grammatical str...
Cortical-hippocampal interactions and cognitive mapping: A hypothesis based on reintegration of the parietal and inferotemporal pathways for visual processing
Tập 17 Số 3 - Trang 230-235 - 1989
Spatial navigation and the firing of hippocampal place cells can be driven as
much by what an animal knows about its spatial world as by what it immediately
experiences at a given location. If presented first with a set of spatially
orienting cues, which are then removed during a test, navigation to a place of
reward is accurate and place cells still fire in their correct locations despite
the abs...
Persistence of sham feeding after intragastric meals in the rat: Concentration-intake relations
Tập 21 Số 1 - Trang 55-59 - 1993
In rats sham fed through esophageal fistulas, responsiveness to sucrose over a
range of concentrations was assessed under two conditions: immediately following
a large intragastric (IG) preload of liquid diet, and after 10 h of deprivation
with no preload. The preload had no reliable effect on sucrose sham feeding at
any sucrose concentration. Therefore, the insensitivity of sham feeding to IG
loa...