Neural activity differs between explicit and implicit learning of artificial grammar strings: An fMRI study
Tóm tắt
Functional magnetic resonance imaging was used to investigate the neural areas underlying retrieval of implicit and explicit knowledge about letter strings. Participants studied strings formed according to an artificial grammar, then performed implicit-learning-based judgments (judging the grammatical status of the string) or explicit-learning-based judgments (recognition) on novel grammatical strings. In comparison with a baseline task, recognition and grammatical judgments led to different patterns of neural activation: Recognition activated the right frontal cortex, whereas grammatical judgment activated the left frontal cortex. Recognition led to higher activity in the precuneus and medial occipital cortex, whereas grammatical judgments led to suppression of activity in the precuneus and activation in the lateral occipital cortex. When the surface structure of the strings was changed, grammatical judgments led to bilateral frontal activity and bilateral but left-lateralized activity in the occipital and parietal lobes. These results provide further evidence for a dissociation between the neural bases of implicit and explicit learning.
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citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=Modality independence of implicitly learned grammatical knowledge; citation_author=G T M Altmann, Z Dienes, A Goode; citation_volume=21; citation_publication_date=1995; citation_pages=899-912; citation_doi=10.1037/0278-7393.21.4.899; citation_id=CR1
citation_title=Implicit learning: Theoretical and practical issues; citation_publication_date=1993; citation_id=CR2; citation_author=D C Berry; citation_author=Z Dienes; citation_publisher=Erlbaum
citation_title=Human cerebral asymmetry; citation_publication_date=1983; citation_id=CR3; citation_author=J Bradshaw; citation_author=N Nettleton; citation_publisher=Prentice-Hall
citation_journal_title=NeuroImage; citation_title=Functional-anatomic study of episodic retrieval: II. Selective averaging of event-related fMRI trials to test the retrieval success hypothesis; citation_author=R L Buckner, W Koutstaal, D L Schacter, A M Dale, M Rotte, B R Rosen; citation_volume=7; citation_publication_date=1998; citation_pages=163-175; citation_doi=10.1006/nimg.1998.0328; citation_id=CR4
citation_journal_title=NeuroImage; citation_title=Functional-anatomic study of episodic retrieval using fMRI; citation_author=R L Buckner, W Koutstaal, D L Schacter, A D Wagner, B R Rosen; citation_volume=7; citation_publication_date=1998; citation_pages=151-162; citation_doi=10.1006/nimg.1998.0327; citation_id=CR5
citation_journal_title=Memory; citation_title=Memory for items and memory for relations in the procedural/declarative memory framework; citation_author=N J Cohen, R A Poldrack, H Eichenbaum; citation_volume=5; citation_publication_date=1997; citation_pages=131-178; citation_doi=10.1080/741941149; citation_id=CR6
citation_journal_title=Neuropsychologia; citation_title=Acquisition of motor skill after bilateral medial temporal-lobe excision; citation_author=S Corkin; citation_volume=6; citation_publication_date=1968; citation_pages=255-265; citation_doi=10.1016/0028-3932(68)90024-9; citation_id=CR7
citation_journal_title=Cognitive Science; citation_title=Mapping across domains without feedback: A neural network model of transfer of implicit knowledge; citation_author=Z Dienes, G T M Altmann, S-J Gao; citation_volume=23; citation_publication_date=1999; citation_pages=53-82; citation_doi=10.1207/s15516709cog2301_3; citation_id=CR8
citation_journal_title=Hippocampus; citation_title=Encoding and retrieval in the human medial temporal lobes: An empirical investigation using functional magnetic resonance imaging; citation_author=R J Dolan, P F Fletcher; citation_volume=9; citation_publication_date=1999; citation_pages=25-34; citation_doi=10.1002/(SICI)1098-1063(1999)9:1<25::AID-HIPO3>3.0.CO;2-4; citation_id=CR9
citation_journal_title=Cerebral Cortex; citation_title=Learning-related neuronal responses in prefrontal cortex studied with functional neuroimaging; citation_author=P Fletcher, C Buchel, O Josephs, K Friston, R Dolan; citation_volume=9; citation_publication_date=1999; citation_pages=168-178; citation_doi=10.1093/cercor/9.2.168; citation_id=CR10
citation_journal_title=Brain; citation_title=Brain activity during memory retrieval: The influence of imagery and semantic cueing; citation_author=P Fletcher, T Shallice, C D Frith, R S J Frackowiak, R J Dolan; citation_volume=119; citation_publication_date=1996; citation_pages=1587-1596; citation_doi=10.1093/brain/119.5.1587; citation_id=CR11
citation_journal_title=Brain; citation_title=The functional roles of prefrontal cortex in episodic memory: II. Retrieval; citation_author=P Fletcher, T Shallice, C D Frith, R S J Frackowiak, R Dolan; citation_volume=121; citation_publication_date=1998; citation_pages=1249-1256; citation_doi=10.1093/brain/121.7.1249; citation_id=CR12
citation_journal_title=NeuroImage; citation_title=Characterizing evoked hemodynamics with fMRI; citation_author=K J Friston, C D Frith, R D Turner, R S J Frackowiak; citation_volume=2; citation_publication_date=1995; citation_pages=157-165; citation_doi=10.1006/nimg.1995.1018; citation_id=CR13
citation_journal_title=Human Brain Mapping; citation_title=Statistical parametric maps in functional imaging: A general linear approach; citation_author=K J Friston, A P Holmes, K J Worsley, J P Poline, C D Frith, R S J Frackowiak; citation_volume=2; citation_publication_date=1995; citation_pages=189-210; citation_doi=10.1002/hbm.460020402; citation_id=CR14
citation_journal_title=Brain & Language; citation_title=Hemisphere differences in the acquisition and use of descriptive systems; citation_author=E Goldberg, L D Costa; citation_volume=14; citation_publication_date=1981; citation_pages=144-173; citation_doi=10.1016/0093-934X(81)90072-9; citation_id=CR15
citation_journal_title=Cognitive Psychology; citation_title=Transfer and complexity in artificial grammar learning; citation_author=R L Gomez; citation_volume=33; citation_publication_date=1997; citation_pages=154-207; citation_doi=10.1006/cogp.1997.0654; citation_id=CR16
citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=What is learned from artificial grammars? Transfer tests of simple association; citation_author=R L Gomez, R W Schvaneveldt; citation_volume=20; citation_publication_date=1994; citation_pages=392-410; citation_doi=10.1037/0278-7393.20.2.396; citation_id=CR17
citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=The information that amnesic patients do not forget; citation_author=P Graf, L R Squire, G Mandler; citation_volume=10; citation_publication_date=1984; citation_pages=164-178; citation_doi=10.1037/0278-7393.10.1.164; citation_id=CR18
citation_journal_title=Journal of Neuroscience; citation_title=Recollection and familiarity in recognition memory: An event-related functional magnetic resonance imaging study; citation_author=R N A Henson, M D Rugg, T Shallice, O Josephs, R J Dolan; citation_volume=19; citation_publication_date=1999; citation_pages=3962-3972; citation_id=CR19
citation_journal_title=Psychological Science; citation_title=Intact artificial grammar learning in amnesia: Dissociation of classification learning and explicit memory for specific instances; citation_author=B J Knowlton, S J Ramus, L R Squire; citation_volume=3; citation_publication_date=1992; citation_pages=172-179; citation_doi=10.1111/j.1467-9280.1992.tb00021.x; citation_id=CR20
citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=The information acquired in artificial grammar learning; citation_author=B J Knowlton, L R Squire; citation_volume=20; citation_publication_date=1994; citation_pages=79-91; citation_doi=10.1037/0278-7393.20.1.79; citation_id=CR21
citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=Artificial grammar learning depends on implicit acquisition of both abstract and exemplar-specific information; citation_author=B J Knowlton, L R Squire; citation_volume=22; citation_publication_date=1996; citation_pages=169-181; citation_doi=10.1037/0278-7393.22.1.169; citation_id=CR22
citation_journal_title=Neuropsychology; citation_title=Dissociations within nondeclarative memory in Huntington’s disease; citation_author=B J Knowlton, L R Squire, J S Paulsen, N R Swerdlow, M Swenson, N Butters; citation_volume=10; citation_publication_date=1996; citation_pages=538-548; citation_doi=10.1037/0894-4105.10.4.538; citation_id=CR23
citation_journal_title=Brain; citation_title=Episodic retrieval activates the precuneus irrespective of the imagery content of work pair associates: A PET study; citation_author=B J Krause, D Schmidt, F M Mottaghy, J Taylor, U Halsband, H Herzog, L Tellmann, H-W Muller-Gartner; citation_volume=122; citation_publication_date=1999; citation_pages=255-263; citation_doi=10.1093/brain/122.2.255; citation_id=CR24
citation_journal_title=NeuroImage; citation_title=Right anterior prefrontal cortex activation during semantic monitoring and working memory; citation_author=A K MacLeod, R L Buckner, F M Miezin, S E Petersen, M E Raichle; citation_volume=7; citation_publication_date=1998; citation_pages=41-48; citation_doi=10.1006/nimg.1997.0308; citation_id=CR25
citation_title=Representing artificial grammars: Transfer across stimulus forms and modalities; citation_inbook_title=How implicit is implicit learning?; citation_publication_date=1997; citation_pages=73-106; citation_id=CR26; citation_author=L Manza; citation_author=A S Reber; citation_publisher=Oxford University Press
citation_journal_title=Journal of Experimental Psychology: Human Perception & Performance; citation_title=Abstract visual-form representations in the left cerebral hemisphere; citation_author=C J Marsolek; citation_volume=21; citation_publication_date=1995; citation_pages=375-386; citation_doi=10.1037/0096-1523.21.2.375; citation_id=CR27
citation_journal_title=Neuropsychology; citation_title=Form-specific explicit and implicit memory in the right cerebral hemisphere; citation_author=C J Marsolek, L R Squire, S M Kosslyn, M E Lulenski; citation_volume=8; citation_publication_date=1994; citation_pages=588-597; citation_doi=10.1037/0894-4105.8.4.588; citation_id=CR28
citation_journal_title=Journal of Experimental Psychology: Learning, Memory, & Cognition; citation_title=Role of implicit and explicit processes in learning from examples: A synergistic effect; citation_author=R C Mathews, R R Buss, W B Stanley, F Blanchard-Fields, J R Cho, B Druhan; citation_volume=15; citation_publication_date=1989; citation_pages=1083-1100; citation_doi=10.1037/0278-7393.15.6.1083; citation_id=CR29
citation_journal_title=Psychological Science; citation_title=Right-hemisphere memory superiority: Studies of a split-brain patient; citation_author=J Metcalfe, M Funnell, M S Gazzaniga; citation_volume=6; citation_publication_date=1995; citation_pages=157-164; citation_doi=10.1111/j.1467-9280.1995.tb00325.x; citation_id=CR30
citation_journal_title=Cognitive Psychology; citation_title=Attentional requirements of learning: Evidence from performance measures; citation_author=M J Nissen, P Bullemer; citation_volume=19; citation_publication_date=1987; citation_pages=1-32; citation_doi=10.1016/0010-0285(87)90002-8; citation_id=CR31
citation_journal_title=Trends in Cognitive Sciences; citation_title=The role of prefrontal cortex during tests of episodic memory; citation_author=S F Nolde, M K Johnson, C L Raye; citation_volume=2; citation_publication_date=1998; citation_pages=399-406; citation_doi=10.1016/S1364-6613(98)01233-9; citation_id=CR32
citation_journal_title=Psychonomic Bulletin & Review; citation_title=PET studies of encoding and retrieval: The HERA model; citation_author=L Nyberg, R Cabeza, E Tulving; citation_volume=3; citation_publication_date=1996; citation_pages=135-148; citation_doi=10.3758/BF03212412; citation_id=CR33
citation_journal_title=Science; citation_title=Activation of extrastriate and frontal cortical areas by visual words and word-like stimuli; citation_author=S E Petersen, P T Fox, A Z Snyder, M E Raichle; citation_volume=249; citation_publication_date=1990; citation_pages=1041-1044; citation_doi=10.1126/science.2396097; citation_id=CR34
citation_journal_title=Neuropsychology; citation_title=Striatal activation during cognitive skill learning; citation_author=R A Poldrack, V Prabhakaran, C A Seger, J D E Gabrieli; citation_volume=13; citation_publication_date=1999; citation_pages=564-574; citation_doi=10.1037/0894-4105.13.4.564; citation_id=CR35
Prabhakaran, V., Rypma, B., & Gabrieli, J. D. E. (in press). Neural substrates of mathematical reasoning: An fMRI study of neocortical activation during performance of the necessary arithmetic operations test. Neuropsychology.
citation_journal_title=Cognitive Psychology; citation_title=Neural substrates of fluid reasoning: An fMRI study of neocortical activation during performance of the Raven’s Progressive Matrices test; citation_author=V Prabhakaran, J A L Smith, J E Desmond, G H Glover, J D E Gabrieli; citation_volume=33; citation_publication_date=1997; citation_pages=43-63; citation_doi=10.1006/cogp.1997.0659; citation_id=CR37
citation_journal_title=Brain; citation_title=Brain activity during reading: The effects of exposure duration and task; citation_author=C J Price, R J S Wise, J D G Watson, K Patterson, D Howard, R S J Frackowiak; citation_volume=117; citation_publication_date=1994; citation_pages=1255-1269; citation_doi=10.1093/brain/117.6.1255; citation_id=CR38
citation_journal_title=Journal of Neuroscience; citation_title=Differential sensitivity of human visual cortex to faces, letter-strings, and textures: A functional magnetic resonance imaging study; citation_author=A Puce, T Allison, M Asgari, J C Gore, G McCarthy; citation_volume=16; citation_publication_date=1996; citation_pages=5205-5215; citation_id=CR39
citation_journal_title=Brain; citation_title=Cerebral organization of component processes in reading; citation_author=K R Pugh, B A Shaywitz, S E Shaywitz, R T Constable, P Skudlarski, R K Fulbright, R A Bronen, D P Shankweiler, L Katz, J M Fletcher, J C Gore; citation_volume=119; citation_publication_date=1996; citation_pages=1221-1238; citation_doi=10.1093/brain/119.4.1221; citation_id=CR40
citation_journal_title=Journal of Verbal Learning & Verbal Behavior; citation_title=Implicit learning of artificial grammars; citation_author=A S Reber; citation_volume=6; citation_publication_date=1967; citation_pages=855-863; citation_doi=10.1016/S0022-5371(67)80149-X; citation_id=CR41
citation_journal_title=Journal of Experimental Psychology; citation_title=Transfer of syntactic structure in synthetic languages; citation_author=A S Reber; citation_volume=81; citation_publication_date=1969; citation_pages=115-119; citation_doi=10.1037/h0027454; citation_id=CR42
citation_journal_title=Journal of Experimental Psychology: General; citation_title=Implicit learning and tacit knowledge; citation_author=A S Reber; citation_volume=118; citation_publication_date=1989; citation_pages=219-235; citation_doi=10.1037/0096-3445.118.3.219; citation_id=CR43
citation_journal_title=Learning & Memory; citation_title=Contrasting cortical activity associated with category memory and recognition; citation_author=P J Reber, C E L Stark, L R Squire; citation_volume=5; citation_publication_date=1998; citation_pages=420-428; citation_id=CR44
citation_journal_title=Proceedings of the National Academy of Sciences; citation_title=Cortical areas supporting category learning identified using functional MRI; citation_author=P J Reber, C E L Stark, L R Squire; citation_volume=95; citation_publication_date=1998; citation_pages=747-750; citation_doi=10.1073/pnas.95.2.747; citation_id=CR45
citation_journal_title=NeuroImage; citation_title=Neural correlates of memory retrieval during recognition memory and cued recall; citation_author=M D Rugg, P C Fletcher, K Allan, C D Frith, R S J Frackowiak, R J Dolan; citation_volume=8; citation_publication_date=1998; citation_pages=262-273; citation_doi=10.1006/nimg.1998.0363; citation_id=CR46
citation_journal_title=Brain; citation_title=Differential activation of the prefrontal cortex in successful and unsuccessful memory retrieval; citation_author=M D Rugg, P C Fletcher, C D Frith, R S Frackowiak, R J Dolan; citation_volume=119; citation_publication_date=1996; citation_pages=2073-2083; citation_doi=10.1093/brain/119.6.2073; citation_id=CR47
citation_journal_title=NeuroImage; citation_title=Late onset of anterior prefrontal activity during true and false recognition: An event-related fMRI study; citation_author=D L Schacter, R L Buckner, W Koutstaal, A M Dale, B R Rosen; citation_volume=6; citation_publication_date=1997; citation_pages=259-269; citation_doi=10.1006/nimg.1997.0305; citation_id=CR48
citation_journal_title=Psychological Bulletin; citation_title=Implicit learning; citation_author=C A Seger; citation_volume=115; citation_publication_date=1994; citation_pages=163-196; citation_doi=10.1037/0033-2909.115.2.163; citation_id=CR49
citation_journal_title=Consciousness & Cognition; citation_title=Independent judgment-linked and motor-linked mechanisms in artificial grammar learning; citation_author=C A Seger; citation_volume=7; citation_publication_date=1998; citation_pages=259-284; citation_doi=10.1006/ccog.1997.0331; citation_id=CR50
citation_journal_title=Neuropsychologia; citation_title=Hemispheric asymmetries and individual differences in visual concept learning as measured by functional MRI; citation_author=C A Seger, R A Poldrack, V Prabhakaran, Z Zhao, G Glover, J D E Gabrieli; citation_volume=38; citation_publication_date=2000; citation_pages=1316-1324; citation_doi=10.1016/S0028-3932(00)00014-2; citation_id=CR51
citation_journal_title=Cerebral Cortex; citation_title=Top-down modulation of early sensory cortex; citation_author=G L Shulman, M Corbetta, R L Buckner, M E Raichle, J A Fiez, F M Miezin, S E Petersen; citation_volume=7; citation_publication_date=1997; citation_pages=193-206; citation_doi=10.1093/cercor/7.3.193; citation_id=CR52
citation_journal_title=Journal of Cognitive Neuroscience; citation_title=Common blood flow changes across visual tasks: II. Decreases in cerebral cortex; citation_author=G L Shulman, J A Fiez, M Corbetta, R L Buckner, F M Miezin, M E Raichle, S E Petersen; citation_volume=9; citation_publication_date=1997; citation_pages=648-663; citation_doi=10.1162/jocn.1997.9.5.648; citation_id=CR53
citation_journal_title=Cognitive Psychology; citation_title=Working memory: A view from neuroimaging; citation_author=E E Smith, J Jonides; citation_volume=33; citation_publication_date=1997; citation_pages=5-42; citation_doi=10.1006/cogp.1997.0658; citation_id=CR54
citation_journal_title=Cognition; citation_title=Alternative strategies of categorization; citation_author=E E Smith, A L Patalano, J Jonides; citation_volume=65; citation_publication_date=1998; citation_pages=167-196; citation_doi=10.1016/S0010-0277(97)00043-7; citation_id=CR55
citation_title=Declarative and nondeclarative memory: Multiple brain systems supporting learning and memory; citation_inbook_title=Memory systems 1994; citation_publication_date=1994; citation_pages=203-232; citation_id=CR56; citation_author=L R Squire; citation_publisher=MIT Press
citation_journal_title=Proceedings of the National Academy of Sciences; citation_title=Activation of the hippocampus in normal humans: A functional anatomical study of memory; citation_author=L R Squire, J G Ojemann, F M Miesin, S E Petersen, T O Videen, M E Raichle; citation_volume=89; citation_publication_date=1992; citation_pages=1837-1841; citation_doi=10.1073/pnas.89.5.1837; citation_id=CR57
citation_title=Co-planar stereotactic atlas of the human brain; citation_publication_date=1988; citation_id=CR58; citation_author=J Talairach; citation_author=P Tournoux; citation_publisher=Thieme
citation_journal_title=Proceedings of the National Academy of Sciences; citation_title=Hemispheric encoding/retrieval asymmetry in episodic memory: Positron emission tomography findings; citation_author=E Tulving, S Kapur, F I M Craik, M Moscovitch, S Houle; citation_volume=91; citation_publication_date=1994; citation_pages=2016-2020; citation_doi=10.1073/pnas.91.6.2016; citation_id=CR59
citation_journal_title=NeuroImage; citation_title=Activation of lateral extrastriate areas during orthographic processing of Japanese characters studied with fMRI; citation_author=I Uchida, H Kikyo, K Nakajima, S Konishi, K Sekihara, Y Miyashita; citation_volume=9; citation_publication_date=1999; citation_pages=208-215; citation_doi=10.1006/nimg.1999.0400; citation_id=CR60
citation_journal_title=Brain; citation_title=Prefrontal cortex and recognition memory Functional-MRI evidence for context-dependent retrieval processes; citation_author=A D Wagner, J E Desmond, G H Glover, J D E Gabrieli; citation_volume=121; citation_publication_date=1997; citation_pages=1985-2002; citation_doi=10.1093/brain/121.10.1985; citation_id=CR61
citation_journal_title=Nature; citation_title=The amnesic syndrome Consolidation or retrieval?; citation_author=E K Warrington, L Weiskrantz; citation_volume=228; citation_publication_date=1970; citation_pages=628-630; citation_doi=10.1038/228628a0; citation_id=CR62
Wharton, C M, Grafman, J, Filename, S K, Hansen, E K, Brainier, J, Marks, A, & Honda, M (1999). The neuroanatomy of analogical reasoning Manuscript submitted for publication.
citation_journal_title=Journal of Computer Assisted Tomography; citation_title=Rapid automated algorithm for aligning and reslicing PET images; citation_author=R P Woods, S R Cherry, J C Mazziota; citation_volume=16; citation_publication_date=1992; citation_pages=620-633; citation_doi=10.1097/00004728-199207000-00024; citation_id=CR64