Pigment Cell and Melanoma Research
SCOPUS (2008-2023)SCIE-ISI
1755-148X
1755-1471
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
DermatologyBiochemistry, Genetics and Molecular Biology (miscellaneous)Oncology
Các bài báo tiêu biểu
Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus ConferenceSummary During the 2011 International Pigment Cell Conference (IPCC), the Vitiligo European Taskforce (VETF) convened a consensus conference on issues of global importance for vitiligo clinical research. As suggested by an international panel of experts, the conference focused on four topics: classification and nomenclature; definition of stable disease; definition ... ... hiện toàn bộ
Tập 25 Số 3 - 2012
Novel MITF targets identified using a two‐step DNA microarray strategySummary Malignant melanoma is a chemotherapy‐resistant cancer with high mortality. Recent advances in our understanding of the disease at the molecular level have indicated that it shares many characteristics with developmental precursors to melanocytes, the mature pigment‐producing cells of the skin and hair follicles. The development of melanocytes absolutely depe... ... hiện toàn bộ
Tập 21 Số 6 - Trang 665-676 - 2008
Re‐evaluation of insect melanogenesis research: Views from the dark sideSummary Melanins (eumelanin and pheomelanin) are synthesized in insects for several purposes including cuticle sclerotization and color patterning, clot formation, organogenesis, and innate immunity. Traditional views of insect immunity detail the storage of pro‐phenoloxidases inside specialized blood cells (hemocytes) and their release upon recognition of foreign b... ... hiện toàn bộ
Tập 30 Số 4 - Trang 386-401 - 2017
Sex‐linked barring in chickens is controlled by the CDKN2A /B tumour suppressor locusSummary Sex‐linked barring, a common plumage colour found in chickens, is characterized by black and white barred feathers. Previous studies have indicated that the white bands are caused by an absence of melanocytes in the feather follicle during the growth of this region. Here, we show that Sex‐linked barring is controlled by the CDKN2A/B... hiện toàn bộ
Tập 23 Số 4 - Trang 521-530 - 2010
The exocyst is required for melanin exocytosis from melanocytes and transfer to keratinocytesAbstract Skin pigmentation involves the production of the pigment melanin by melanocytes, in melanosomes and subsequent transfer to keratinocytes. Within keratinocytes, melanin polarizes to the apical perinuclear region to form a protective cap, shielding the DNA from ultraviolet radiation‐induced damage. Previously, we found evidence to support the exocytosis by me... ... hiện toàn bộ
Tập 33 Số 2 - Trang 366-371 - 2020
Identification of differentially expressed genes in spontaneously regressing melanoma using the MeLiM Swine ModelSummary Partial and some few cases of complete spontaneous regression have been observed in cutaneous melanoma patients but little is known about the molecular mechanisms involved. The Melanoblastoma‐bearing Libechov Minipig (MeLiM) is a suitable animal model to study the phenomenon of spontaneous regression because MeLiM pigs exhibit naturally occurring melanomas w... ... hiện toàn bộ
Tập 21 Số 2 - Trang 147-161 - 2008
Identification of unique sensitizing targets for anti‐inflammatory CDDO ‐M e in metastatic melanoma by a large‐scale synthetic lethal RNA i screeningSummary CDDO ‐M e has been shown to exert potent anti‐inflammatory activity for chronic kidney disease and antitumor activity for several tumors, including melanoma, in early clinical trials. To improve CDD...
Tập 26 Số 1 - Trang 97-112 - 2013
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: A valuable model for studying the impact of genetic diversity in melanomaAbstract Melanoma is a disease associated with a very high mutation burden and thus the possibility of a diverse range of oncogenic mechanisms that allow it to evade therapeutic interventions and the immune system. Here, we describe the characterization of a panel of 102 cell lines from metastatic melanomas (the NZM lines), including using whole‐exome and RNA sequen... ... hiện toàn bộ
Tập 34 Số 1 - Trang 136-143 - 2021
Nghiên cứu liên kết toàn bộ bộ gen xác định CDH13 là một gen dễ bị mắc bệnh bạch biến gây ra bởi rhododendrol Dịch bởi AI Tóm tắt RS‐4‐(4‐hydroxyphenyl)‐2‐butanol dạng racemic (rhododendrol; tên thương mại: Rhododenol [RD]), được sử dụng trong mỹ phẩm làm trắng da, đã gây bất ngờ ở Nhật Bản khi báo cáo gây ra bạch biến hoặc bệnh bạch tạng gọi là bạch biến do rhododendrol (RIL) sau khi sử dụng nhiều lần. Theo hiểu biết của chúng tôi, chưa có nghiên cứu nào điều tra cơ chế gây bệnh bạch ... ... hiện toàn bộ
Tập 33 Số 6 - Trang 826-833 - 2020
#GWAS #RIL #CDH13 #bạch biến #rhododendrol #tyrosinase #hóa cảm #T-cadherin #tự hủy