Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference

Pigment Cell and Melanoma Research - Tập 25 Số 3 - 2012
Khaled Ezzedine1,2,3, Henry W. Lim4, Tamio Suzuki5, Ichiro Katayama6, Iltefat Hamzavi4, C. Lan7, Boon Kee Goh8, Tag S. Anbar9, Carla Castro10, Azalea Lee11, Davinder Parsad12, Nanja van Geel13, I. Caroline Le Poole14, Naoki Oiso15, Laïla Benzekri16, Richard A. Spritz17, Yvon Gauthier1,2,3, Seung Kyung Hann18, Mauro Picardo19, Alain Taı̈eb1,2,3
1Department of Dermatology and Pediatric Dermatology
2National Centre for Rare Skin Disorders, Hôpital Pellegrin, Bordeaux, France
3University of Bordeaux, Biothérapie des maladies géniques et cancers, U1035, Bordeaux, France
4Department of Dermatology, Henry Ford Hospital, Detroit, Mi USA
5Department of Dermatology, Yamagata University School of Medicine, Yamagata, Japan
6Department of Dermatology, Graduate School of Medicine, Osaka University, Osaka, Japan
7Department of Dermatology, Kaohsiung Medical University, Kaohsiung City, Taiwan
8National Skin Centre, Singapore, Singapore
9Department of Dermatology, Al-Minya University, Al-Minya, Egypt
10Department of Dermatology, Santa Casa de Misericórdia Hospital, Pontifical and Catholic University of Paraná, Curitiba, Parana, Brazil
11Department of Dermatology, Dongguk University Ilsan Hospital, Gyeonggi-do, South Korea
12Department of Dermatology, PGIMER, Chandigarh, India
13Department of Dermatology, Ghent University Hospital, Ghent, Belgium
14Departments of Pathology, Microbiology and Immunology, Oncology Institute, Loyola University Chicago, Chicago, IL, USA
15Department of Dermatology, Kinki University School of Medicine, Osaka, Japan
16Department of Dermatology, Ibn Sina University Hospital, Rabat, Morocco and Mohammed V Souissi University, Rabat, Morocco
17Human Medical Genetics Program and Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA
18Korea Institute of Vitiligo Research, Drs. Woo & Hann’s Skin Center, Seoul, South Korea
19San Gallicano Dermatologic Institute, Via Elio Chianesi, Roma, Italy

Tóm tắt

SummaryDuring the 2011 International Pigment Cell Conference (IPCC), the Vitiligo European Taskforce (VETF) convened a consensus conference on issues of global importance for vitiligo clinical research. As suggested by an international panel of experts, the conference focused on four topics: classification and nomenclature; definition of stable disease; definition of Koebner’s phenomenon (KP); and ‘autoimmune vitiligo’. These topics were discussed in seven working groups representing different geographical regions. A consensus emerged that segmental vitiligo be classified separately from all other forms of vitiligo and that the term ‘vitiligo’ be used as an umbrella term for all non‐segmental forms of vitiligo, including ‘mixed vitiligo’ in which segmental and non‐segmental vitiligo are combined and which is considered a subgroup of vitiligo. Further, the conference recommends that disease stability be best assessed based on the stability of individual lesions rather than the overall stability of the disease as the latter is difficult to define precisely and reliably. The conference also endorsed the classification of KP for vitiligo as proposed by the VETF (history based, clinical observation based, or experimentally induced). Lastly, the conference agreed that ‘autoimmune vitiligo’ should not be used as a separate classification as published evidence indicates that the pathophysiology of all forms of vitiligo likely involves autoimmune or inflammatory mechanisms.

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Pigment Cell and Melanoma Research

Tập 25 Số 3

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