Pathology International
SCOPUS (1951-2025)SCIE-ISI
1320-5463
1440-1827
Anh Quốc
Cơ quản chủ quản: Wiley-Blackwell Publishing Ltd , WILEY
Lĩnh vực:
Medicine (miscellaneous)Pathology and Forensic Medicine
Phân tích ảnh hưởng
Các bài báo tiêu biểu
The World Health Organization classification of malignant lymphomas in Japan: Incidence of recently recognized entities
Tập 50 Số 9 - Trang 696-702 - 2000
New insights into the immunology and genetics of malignant lymphomas have
allowed the recognition of new entities and the refinement of previously
recognized disease categories. The relative incidence of these subtypes of
malignant lymphoma is also known to differ according to geographic location. In
order to clarify the current status of malignant lymphomas in Japan and the
relative incidences of...
Tight junction‐related human diseases
Tập 63 Số 1 - Trang 1-12 - 2013
Tight junctions are intercellular junctions adjacent to the apical ends of
paracellular spaces. They have two classical functions, the barrier function and
the fence function. The former regulates the passage of ions, water and various
molecules through paracellular spaces, and is thus related to edema, jaundice,
diarrhea and blood‐borne metastasis. The latter function maintains cell polarity
by f...
NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment
Tập 68 Số 11 - Trang 583-595 - 2018
NUT carcinoma (NC) is a rare, aggressive subtype of squamous cell carcinoma
defined by rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion
oncoproteins resulting from chromosomal translocation, most commonly BRD4‐NUT.
This is a nearly uniformly lethal cancer affecting patients of all ages, but
predominantly teens and young adults. The cell of origin is unknown, but NC most
common...
Role of tumor‐associated macrophages in human malignancies: friend or foe?
Tập 66 Số 9 - Trang 491-505 - 2016
Tumor‐associated macrophages (TAMs) play a pivotal role in tumor growth in human
malignancies. Published studies have analyzed the relationship between TAM
infiltration and the prognosis of patients for many human tumors. Most studies
reported a positive correlation between TAM density and a poor prognosis.
Studies focusing on macrophage phenotypes emphasized the protumor role of M2
anti‐inflammat...
The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis‐resistance to non‐thermal plasma therapy
Tập 66 Số 5 - Trang 245-259 - 2016
Helmut Sies established the concept of oxidative stress in 1985. However, it
took some time to introduce this concept into pathology, where investigators
count on formalin‐fixed paraffin‐embedded tissue sections. I sought out antigens
for this purpose based on an oxidative stress‐induced rat renal carcinogenesis
model, which revealed that 8‐hydroxy‐2′‐deoxyguanosine and
4‐hydroxy‐2‐nonenal‐modifie...
Organ‐specific endoglin (CD105) expression in the angiogenesis of human cancers
Tập 56 Số 12 - Trang 717-723 - 2006
Some markers of angiogenic endothelial cells are emerging as targets for cancer
therapy. The present study compared the expression of CD105 with that of other
endothelial markers in cancers from various organs. Surgically resected cancer
tissues from 188 patients comprising brain (n = 17), lung (n = 38), breast
(n = 30), stomach (n = 30), colon (n = 31), liver (n = 32), and kidney (n = 10)
cancers...
Age‐related EBV‐associated B‐cell lymphoproliferative disorders: Diagnostic approach to a newly recognized clinicopathological entity
Tập 59 Số 12 - Trang 835-843 - 2009
EBV is prevalent among healthy individuals, and is implicated in numerous
reactive and neoplastic processes in the immune system. The authors originally
identified a series of senile or age‐related EBV‐associated B‐cell
lymphoproliferative disorders (LPD) bearing a resemblance to
immunodeficiency‐associated ones, which may be associated with immune senescence
in the elderly and which are now incor...
Bizarre parosteal osteochondromatous proliferation (Nora’s lesion) of the foot
Tập 51 Số 10 - Trang 816-823 - 2001
A 22‐year‐old man presented with a growing lump on the fifth metatarsal of the
right foot. Radiographically, the lesion was a calcified mass stuck on to the
bone. The T2‐weighted magnetic resonance images showed heterogeneity in
intensity. A tumor was suspected and an excisional biopsy was done. The lesion
was composed of a cartilaginous cap and bone tissue. Histological examination
revealed chara...
Altered expression of microRNA miR‐21, miR‐155, and let‐7a and their roles in pulmonary neuroendocrine tumors
Tập 62 Số 9 - Trang 583-591 - 2012
MicroRNA (miRNA) has a critical effect on tumorigenesis through
post‐transcriptional modification and is considered to be potential biomarkers
for cancer diagnosis and treatment monitoring. We evaluated the expression
pattern of three selected miRNAs (miR‐21, miR‐155, and let‐7a) to evaluate their
potential roles by quantitative reverse transcription‐polymerase chain reaction
using formalin‐fixed ...
Comparative study of histological features between core needle biopsy and surgical excision in phyllodes tumor
Tập 62 Số 2 - Trang 120-126 - 2012
We analyzed histopathological features of core needle biopsy (CNB) and surgical
excision specimen comparatively in 129 patients with surgically proven phyllodes
tumor (PT). Stromal characteristics including cellularity, atypia, mitosis,
overgrowth, tissue fragmentation, and the tumor margin were assessed.
Benign/borderline/malignant phyllodes tumor (PT) were diagnosed in 90 (69.8%)/30
(23.3%)/9 (7...