Neuropathology and Applied Neurobiology
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Sub‐acute cerebellar degeneration with anti‐Yo autoantibodies: immunohistochemical analysis of the immune reaction in the central nervous system
Neuropathology and Applied Neurobiology - Tập 23 Số 6 - Trang 468-474 - 1997
B. Giometto, G. C. Marchiori, P. Nicolao, T. Scaravilli, A. Lion, P. G. Bardin
and B. Tavolato (1997) Neuropathology and Applied Neurobiology, 23,
468–474Sub‐acute cerebellar degeneration without any anti‐Yo autoantibodies:
immunomstochemical analysis of the immune reaction in the central nervous
systemWe report the pathological findings of a woman with a sub‐acute cerebellar
syndrome who had unde...
Review
Neuropathology and Applied Neurobiology - Tập 24 Số 2 - Trang 104-117 - 1998
P. G. Ince, J. Lowe and P. J. Shaw (1998) Neuropathology and Applied
Neurobiology24, 104–117Amyotrophic lateral sclerosis: current issues in
classification, pathogenesis and molecular pathologyThe classification of
amyotrophic lateral sclerosis (ALS) is reconsidered in the light of developments
in the molecular pathogenesis and histopathology of the condition. A current
view is encapsulated in the...
Protein misfolding in neurodegenerative diseases
Neuropathology and Applied Neurobiology - Tập 30 Số 3 - Trang 215-224 - 2004
A common pathogenic mechanism shared by diverse neurodegenerative disorders,
like Alzheimer's disease, Parkinson's disease, Huntington's disease and
transmissible spongiform encephalopathies, may be altered protein homeostasis
leading to protein misfolding and aggregation of a wide variety of different
proteins in the form of insoluble fibrils. Mutations in the genes encoding
protein constituents ...
EXPERIMENTAL BILATERAL CAROTID ARTERY OCCLUSION: A STUDY OF THE OPTIC NERVE IN THE RAT
Neuropathology and Applied Neurobiology - Tập 10 Số 6 - Trang 423-428 - 1984
Experimental bilateral carotid artery occlusion: a study of the optic nerve in
the ratThe presence of marked changes in the neural retina and retinal vessels
of Long‐Evans pigmented rat following bilateral carotid ligation has been
previously documented by serial ophthalmologic examinations. Light and electron
microscopic studies of the optic nerve in this experimental animal model
revealed advanc...
ASTROCYTE MITOSES AND ALZHEIMER TYPE I AND II ASTROCYTES IN ANOXIC ENCEPHALOPATHY
Neuropathology and Applied Neurobiology - Tập 2 Số 4 - Trang 313-321 - 1976
Astrocyte mitoses and Alzheimer type I and I1 astrocytes in anoxic
en‐cephalopathyNumerous astrocyte mitoses, arrested in metaphase, were found in
a case of anoxic encephalopathy. The number of chromosomes was not excessive,
but in most the mitotic spindles appeared absent. Many Alzheimer type I and II
astrocytes were also seen, together with a few cells containing both micronuclei
and free chromo...
Human adult neurogenesis across the ages: An immunohistochemical study
Neuropathology and Applied Neurobiology - Tập 42 Số 7 - Trang 621-638 - 2016
AbstractAimsNeurogenesis in the postnatal human brain occurs in two neurogenic
niches; the subventricular zone (SVZ) in the wall of the lateral ventricles and
the subgranular zone (SGZ) of the hippocampus. The extent to which this
physiological process continues into adulthood is an area of ongoing research.
This study aimed to characterize markers of cell proliferation and assess the
efficacy of ...
Aberrant microRNA expression in the brains of neurodegenerative diseases: miR‐29a decreased in Alzheimer disease brains targets neurone navigator 3
Neuropathology and Applied Neurobiology - Tập 36 Số 4 - Trang 320-330 - 2010
M. Shioya, S. Obayashi, H. Tabunoki, K. Arima, Y. Saito, T. Ishida and J. Satoh
(2010) Neuropathology and Applied Neurobiology36, 320–330
Aberrant microRNA
expression in the brains of neurodegenerative diseases: miR‐29a decreased in
Alzheimer disease brains targets neurone navigator 3 Aims: MicroRNAs (miRNAs)
are small non‐coding RNAs that regulate translational repression of target
mRNAs. Accumul...
EFFECTS OF METHYLMERCURY ON IN VIVO PROTEIN SYNTHESIS IN ISOLATED CEREBRAL AND CEREBELLAR NEURONS
Neuropathology and Applied Neurobiology - Tập 3 Số 4 - Trang 225-236 - 1977
Effects of methylmercury on in vivo protein synthesis in isolated cerebral and
cerebellar neuronsA preparative method is described for the bulk isolation of
two neuronal populations from cerebellum, namely the granule cell and Purkinje
cell bodies. This isolation method was used for studying in vivo effects of
methylmercury on protein synthesis. The experimental rats were given a single
i.p. dose ...
THE DEVELOPMENT OF THE HUMAN BLOOD‐BRAIN AND BLOOD‐CSF BARRIERS
Neuropathology and Applied Neurobiology - Tập 12 Số 4 - Trang 337-358 - 1986
The development of the human blood‐brain and blood‐CSF barriersThe commonly held
belief that the fetal blood‐brain and blood‐CSF barriers are immature is
reviewed. Results obtained from carefully conducted experiments with horseradish
peroxidase and optimal freeze‐fracturing suggest that the chick, rat and monkey
brain barrier systems to proteins are tight from the earliest stages of
development. ...
THE PATTERN OF RECOVERY OF AXONS IN THE NERVOUS SYSTEM OF RATS FOLLOWING 2,5‐HEXANEDIOL INTOXICATION: A QUESTION OF RHEOLOGY?
Neuropathology and Applied Neurobiology - Tập 8 Số 1 - Trang 19-34 - 1982
Cavanagh J.B. (1982) Neuropathology and Applied Neurobiology 8, 19–34The pattern
of recovery of axons in the nervous system of rats following 2,5‐hexanediol
intoxication: a question of rheology?Rats have been dosed with 2, 5‐hexanediol
for 48 days and then allowed to recover. The changes in the accumulations of
neurofilamentous masses in various pathways in CNS and PNS have been followed by
light ...
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