EXPERIMENTAL BILATERAL CAROTID ARTERY OCCLUSION: A STUDY OF THE OPTIC NERVE IN THE RAT

Neuropathology and Applied Neurobiology - Tập 10 Số 6 - Trang 423-428 - 1984
Junichi Takamatsu1, Atsushi Hirano1, Dana Levy2, Paul Henkind2
1Bluestone Laboratory of the Division of Neuropathology, Department of Pathology
2*Department of Ophthalmology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, New York 10467

Tóm tắt

Experimental bilateral carotid artery occlusion: a study of the optic nerve in the ratThe presence of marked changes in the neural retina and retinal vessels of Long‐Evans pigmented rat following bilateral carotid ligation has been previously documented by serial ophthalmologic examinations. Light and electron microscopic studies of the optic nerve in this experimental animal model revealed advanced optic nerve atrophy in ten of twelve rats examined. There was no significant pathology in either the retina or optic nerve in the remaining two rats after carotid ligation or in the sham‐operated controls.

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Tài liệu tham khảo

10.1037/h0071238

10.1136/bjo.38.8.472

Greene E.C., 1963, Anatomy of the Rat, 177

10.1016/0002-9394(70)91859-3

Hirano A., 1972, Structure and Function of the Nervous Tissue, 73

10.1007/BF00696570

10.1212/WNL.22.5.510

Klatzo I., 1979, Recent Advances in Neuropathology, 27

Knox D.L., 1971, Slowly progressive ischemic optic neuropathy: a clinicopathologic case report, Transactions American Academy Ophthalmology and Otolaryngology, 75, 106

Levine S., 1960, Ischemic infarction and swelling in the rat brain, Archives of Pathology, 69, 544

10.1016/0014-4886(66)90062-8

Miller N.R., 1982, Walsh and Hoyt's Clinical Neuro‐ophthalmology, 329

Miller N.R., 1982, Walsh and Hoyt's Clinical Neuro‐ophthalmology, 41

10.1007/BF00687536

10.3181/00379727-120-30487

Quigley H.A., 1977, Descending optic nerve degeneration in primates, Investigative Ophthalmology Visual Science, 16, 841

10.1016/S0002-9394(14)76086-6

10.1136/bjo.68.1.47

10.1002/cne.901400204

Yanoff M., 1975, Ocular Pathology, 483

Zeman W., 1963, Craigie's Neuroanatomy of the Rat, 11

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Thông tin xuất bản

Neuropathology and Applied Neurobiology

Tập 10 Số 6

423-428

Thông tin tác giả