ASTROCYTE MITOSES AND ALZHEIMER TYPE I AND II ASTROCYTES IN ANOXIC ENCEPHALOPATHY

Neuropathology and Applied Neurobiology - Tập 2 Số 4 - Trang 313-321 - 1976
Nils Henrik Diemer1, L. Klinken1
1Institute of Neuropathology, University of Copenhagen, 16 Juliane Mariesvej, DK‐2100 Copenhagen, Denmark

Tóm tắt

Astrocyte mitoses and Alzheimer type I and I1 astrocytes in anoxic en‐cephalopathyNumerous astrocyte mitoses, arrested in metaphase, were found in a case of anoxic encephalopathy. The number of chromosomes was not excessive, but in most the mitotic spindles appeared absent. Many Alzheimer type I and II astrocytes were also seen, together with a few cells containing both micronuclei and free chromosomes. The occurrence of such transitional forms supports the hypothesis that astrocyte mitoses arrested in metaphase constitute an intermediate stage in the formation of the tetraploid Alzheimer type I astrocytes from cells of Alzheimer type II.

Từ khóa


Tài liệu tham khảo

ADAMS R. D., 1953, The neurological disorder associated with liver disease, Research Publications of the Association for Research into Nervous and Mental Disease, 32, 198

10.1093/brain/81.1.93

BIELSCHOWSKY M., 1931, Symmetrische Einschmelzungsherde im Stirnhirn beim Wilson‐Pseudosklerose‐komplex, Journal für Psychologie und Neurologie (Leipzig), 42, 177

CAVANAGH J. B., 1969, Perfusion fixation, colchicine and mitotic activity in the adult rat brain, Journal of Anatomy (London), 104, 341

CAVANAGH J. B., 1970, The proliferation of astrocytes around a needle wound in the rat brain, Journal of Anatomy (London), 106, 471

10.1016/0022-510X(71)90061-X

CAVANAGH J. B., 1974, Brain dysfunction in metabolic disorders. Research Publications of the Association for Research into Nervous and Mental Disease, 13

CHOU S. M., 1975, Hypertrophic astroglia with arrested mitosis in central pontine myelinolysis (CPM). American Association of Neuropathologists, 50th Annual Meeting, Boston, Massachusetts. Abstract No. 7, Journal of Neuropathology and Experimental Neurology, 34, 77

GREENFIELD J. G., 1963, Greenfield's Neuropathology, 50

HALL H. C., 1921, Maladie de Wilson–Pseudosclérose

KJELDSBERG C. R., 1971, Pathology of the Nervous system, 2952

10.1097/00005072-196304000-00009

LAPHAM L. W., 1962, Cytologic and cytochemical studies of neuroglia. I. A study of the problem of amitosis in reactive protoplasmic astrocytes, American Journal of Pathology, 41, 1

10.1111/j.1601-5223.1954.tb02968.x

10.1007/BF02865108

PENFIELD W., 1932, Cytology and Cellular Pathology of the Nervous System, 453

RUBINSTEIN L. J., 1972, Atlas of Tumor Pathology, fascicle 6, 46

SEITELBERGER F., 1973, Zentrale pontine myelinolyse, Schweizer Archiv für Neurologie, Neurochirurgie und Psychiatrie, 112, 285

SHERLOCK S., 1968, Diseases of the liver and biliary system, 463

SHOLPO A. E., 1957, The human brain in figures and tables, 18

SPIELMEYER W., 1920, Die histipatologische Zusammengehörigkeit der Wilsonschen Krankheit und der Pseudosklerose, Zeitschrift für die gesamte Neurologie und Psychiatrie, 154, 626

STEEGMANN A. T., 1971, Pathology of the Nervous System, 1005

10.1007/BF02866030

10.1097/00005053-194210000-00005

10.1097/00005072-197507000-00001

WOLFF J. R., 1970, Proceedings of the VIth International Congress of Neuropathology, 327

Thông tin
Thông tin xuất bản

Neuropathology and Applied Neurobiology

Tập 2 Số 4

313-321

Thông tin tác giả