Review: Activation patterns of microglia and their identification in the human brain Tập 39 Số 1 - Trang 3-18 - 2013
Delphine Boche, V. Hugh Perry, James A. R. Nicoll
Microglia in the central nervous system are usually maintained in a quiescent state. When activated, they can perform many diverse functions which may be either beneficial or harmful depending on the situation. Although microglial activation may be accompanied by changes in morphology, morphological changes cannot accurately predict the function being undertaken by a microglial cell. Studi...... hiện toàn bộ WHO 2016 Classification of gliomas Tập 44 Số 2 - Trang 139-150 - 2018
Pieter Wesseling, David Capper
AbstractGliomas are the most frequent intrinsic tumours of the central nervous system and encompass two principle subgroups: diffuse gliomas and gliomas showing a more circumscribed growth pattern (‘nondiffuse gliomas’). In the revised fourth edition of the WHO Classification of ... hiện toàn bộ Aberrant microRNA expression in the brains of neurodegenerative diseases: miR‐29a decreased in Alzheimer disease brains targets neurone navigator 3 Tập 36 Số 4 - Trang 320-330 - 2010
Mao Shioya, Shinya Obayashi, Hiroko Tabunoki, Kunimasa Arima, Yumiko Saito, T. Ishida, Jun‐ichi Satoh
M. Shioya, S. Obayashi, H. Tabunoki, K. Arima, Y. Saito, T. Ishida and J. Satoh (2010) Neuropathology and Applied Neurobiology36, 320–330
Aberrant microRNA expression in the brains of neurodegenerative diseases: miR‐29a decreased in Alzheimer disease brains targets neurone navigator 3 Aims:...... hiện toàn bộ Review: The role of vitamin D in nervous system health and disease Tập 39 Số 5 - Trang 458-484 - 2013
Gabriele C. DeLuca, Samantha Kimball, James Kolasinski, Sreeram Ramagopalan, George C. Ebers
Vitamin D and its metabolites have pleomorphic roles in both nervous system health and disease. Animal models have been paramount in contributing to our knowledge and understanding of the consequences of vitamin D deficiency on brain development and its implications f...... hiện toàn bộ Review Tập 24 Số 2 - Trang 104-117 - 1998
Paul G. Ince, James Lowe, Pamela J. Shaw
P. G. Ince, J. Lowe and P. J. Shaw (1998) Neuropathology and Applied Neurobiology24, 104–117Amyotrophic lateral sclerosis: current issues in classification, pathogenesis and molecular pathologyThe classification of amyotrophic lateral sclerosis (ALS) is reconsidered in the light of developments in the molec...... hiện toàn bộ Human adult neurogenesis across the ages: An immunohistochemical study Tập 42 Số 7 - Trang 621-638 - 2016
Claude Dennis, Lisa S. Suh, Michael Rodriguez, Jillian J. Kril, Greg T. Sutherland
AbstractAimsNeurogenesis in the postnatal human brain occurs in two neurogenic niches; the subventricular zone (SVZ) in the wall of the lateral ventricles and the subgranular zone (SGZ) of the hippocampus. Th...... hiện toàn bộ REVIEW: tau protein pathology in Alzheimer’s disease and related disorders Tập 25 Số 3 - Trang 171-187 - 1999
Markus Tolnay, V PROBST
Abundant neurofibrillary lesions made of hyperphosphorylated microtubule‐associated protein tau constitute one of the defining neuropathological features of Alzheimer’s disease. However, tau containing filamentous inclusions in neurones and/or glial cells also define a number of other neurodegenerative disorders clinically characterized by dementia and/or motor syndromes. All these disorde...... hiện toàn bộ Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule‐binding repeat domains as demonstrated by new specific monoclonal antibodies Tập 29 Số 3 - Trang 288-302 - 2003
R. De Silva, Tammaryn Lashley, G M Gibb, Diane P. Hanger, A. Hope, A R Reid, Rina Bandopadhyay, Michelle A. Utton, Catherine Strand, T.P. Jowett, Naheed L. Khan, Brian H. Anderton, Nicholas Wood, Janice L. Holton, Tamás Révész, Andrew J. Lees
Pathological inclusions containing fibrillar aggregates of hyperphosphorylated tau protein are a characteristic feature in the tauopathies, which include Alzheimer's disease, frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP‐17), progressive supranuclear palsy, corticobasal degeneration and Pick's disease. Tau isoform composition and cellular and regional distribution...... hiện toàn bộ