A COMPARATIVE STUDY OF MODIFIED BIELSCHOWSKY, BODIAN AND THIOFLAVIN S STAINS ON ALZHEIMER'S NEUROFIBRILLARY TANGLES

Neuropathology and Applied Neurobiology - Tập 12 Số 1 - Trang 3-9 - 1986
Toru Yamamoto1, Atsushi Hirano1
1Bluestone Laboratory of the Division of Neuropathology, Department of Pathology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA

Tóm tắt

Serial sections of the brains of two cases with Alzheimer's disease were stained with the standard Bodian, modified Bielschowsky (reformed Gros‐Schultze's modification) and thioflavin S methods. The numbers of demonstrated Alzheimer's neurofibrillary tangles (NFTs) were different between the two silver stains: from 15 to 75% more NFTs were shown and more distinctly with the modified Bielschowsky stain than with the Bodian stain. Many of the NFTs in both cases were of eosinophilic and less argentophilic type. Although the NFTs were not counted, the thioflavin S stain seemed to have no apparent advantage over the modified Bielschowsky stain in the demonstration of NFTs.

Từ khóa


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Thông tin
Thông tin xuất bản

Neuropathology and Applied Neurobiology

Tập 12 Số 1

3-9

Thông tin tác giả