Microbial Cell Factories

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Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum
Microbial Cell Factories - Tập 8 - Trang 1-15 - 2009
Yohei Shinfuku, Natee Sorpitiporn, Masahiro Sono, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu
In silico genome-scale metabolic models enable the analysis of the characteristics of metabolic systems of organisms. In this study, we reconstructed a genome-scale metabolic model of Corynebacterium glutamicum on the basis of genome sequence annotation and physiological data. The metabolic characteristics were analyzed using flux balance analysis (FBA), and the results of FBA were validated using... hiện toàn bộ
Increased production of inosine and guanosine by means of metabolic engineering of the purine pathway in Ashbya gossypii
Microbial Cell Factories - - 2015
Rodrigo Ledesma‐Amaro, Rubén M. Buey, José Luis Revuelta
Antibiotic-free selection in E. coli: new considerations for optimal design and improved production
Microbial Cell Factories - Tập 9 - Trang 1-10 - 2010
Isabelle Peubez, Nicolas Chaudet, Charlotte Mignon, Géraldine Hild, Stéphanie Husson, Virginie Courtois, Karelle De Luca, Denis Speck, Régis Sodoyer
The increasing regulatory requirements to which biological agents are subjected will have a great impact in the field of industrial protein expression and production. There is an expectation that in a near future, there may be "zero tolerance" towards antibiotic-based selection and production systems. Besides the antibiotic itself, the antibiotic resistance gene is an important consideration. The ... hiện toàn bộ
Recombinant expression of disulfide-rich proteins: carboxypeptidase inhibitors as model proteins
Microbial Cell Factories - Tập 5 - Trang 1-2 - 2006
Laura Sanglas, Sílvia Bronsoms, Joan L Arolas, Julia Lorenzo, Francesc X Aviles
Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b
Microbial Cell Factories - Tập 10 - Trang 1-13 - 2011
Najla Gasmi, Atef Ayed, Jean-Marc Nicaud, Héla Kallel
The non conventional yeast Yarrowia lipolytica has aroused a strong industrial interest for heterologous protein production. However most of the studies describing recombinant protein production by this yeast rely on the use of complex media, such media are not convenient for large scale production particularly for products intended for pharmaceutical applications. In addition medium composition c... hiện toàn bộ
Recombinant lipase immobilised in the cell wall of Bacillus halodurans Alk 36 exploiting the FliC protein
Microbial Cell Factories - Tập 5 Số S1 - 2006
Michael Crampton, Erika du Plessis, Santosh Ramchuran, Eldie Berger, Maureen E. Louw
Efficient production of α-acetolactate by whole cell catalytic transformation of fermentation-derived pyruvate
Microbial Cell Factories - Tập 18 - Trang 1-11 - 2019
Robin Dorau, Lin Chen, Jianming Liu, Peter Ruhdal Jensen, Christian Solem
Diacetyl provides the buttery aroma in products such as butter and margarine. It can be made via a harsh set of chemical reactions from sugarcane bagasse, however, in dairy products it is normally formed spontaneously from α-acetolactate, a compound generated by selected lactic acid bacteria in the starter culture used. Due to its bacteriostatic properties, it is difficult to achieve high levels o... hiện toàn bộ
Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae
Microbial Cell Factories - Tập 14 Số 1 - 2015
Jifeng Yuan, Chi‐Bun Ching
A novel genetic system for recombinant protein secretion in the Antarctic Pseudoalteromonas haloplanktis TAC125
Microbial Cell Factories - Tập 5 - Trang 1-8 - 2006
Angela Maria Cusano, Ermenegilda Parrilli, Gennaro Marino, Maria Luisa Tutino
The final aim of recombinant protein production is both to have a high specific production rate and a high product quality. It was already shown that using cold-adapted bacteria as host vectors, some "intractable" proteins can be efficiently produced at temperature as low as 4°C. A novel genetic system for the production and secretion of recombinant proteins in the Antarctic Gram-negative bacteriu... hiện toàn bộ
Rhamnolipid thiết kế thông qua giảm đa dạng congener: sản xuất và đặc trưng Dịch bởi AI
Microbial Cell Factories - Tập 16 - Trang 1-14 - 2017
Till Tiso, Rabea Zauter, Hannah Tulke, Bernd Leuchtle, Wing-Jin Li, Beate Behrens, Andreas Wittgens, Frank Rosenau, Heiko Hayen, Lars Mathias Blank
Rhamnolipid là các biosurfactant có tính chất hoạt động bề mặt làm cho chúng phù hợp cho một loạt các ứng dụng công nghiệp. Những tính chất này bao gồm khả năng nhũ hóa và tạo bọt, nồng độ micelle quan trọng, và khả năng giảm sức căng bề mặt. Hơn nữa, các khía cạnh như độ tương thích sinh học và tính thân thiện với môi trường đang ngày càng trở nên quan trọng. Rhamnolipid chủ yếu được sản xuất bởi... hiện toàn bộ
#rhamnolipid #biosurfactant #Pseudomonas putida #sinh học tổng hợp #carbon bền vững
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