Macromolecular Bioscience
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
pH‐temperature Responsive Hydrogel‐Mediated Delivery of Exendin‐4 Encapsulated Chitosan Nanospheres for Sustained Therapeutic Efficacy in Type 2 Diabetes Mellitus
Macromolecular Bioscience - Tập 23 Số 11 - 2023
AbstractType 2 Diabetes Mellitus (T2D) is a chronic, obesity‐related, and
inflammatory disorder characterize by insulin resistance, inadequate insulin
secretion, hyperglycemia, and excessive glucagon secretion. Exendin‐4 (EX), a
clinically established antidiabetic medication that acts as a glucagon‐like
peptide‐1 receptor agonist, is effective in lowering glucose levels and
stimulating insulin sec...
Mitogenic Activity of Sulfated Chitosan and Cellulose Derivatives is Related to Protection of FGF‐2 from Proteolytic Cleavage
Macromolecular Bioscience - Tập 12 Số 6 - Trang 740-750 - 2012
AbstractNovel chitosan (CHS) and cellulose sulfates (CSs) are studied regarding
their mitogenic activity and their protective effect against proteolytic
digestion of FGF‐2. An intermediate degree of sulfation (DSS) and lower
concentration of CHS have superior effect on 3T3 cell growth while the mitogenic
activity of CS increases with DSS and concentration. Experiments with trypsin as
model protein...
Super-Anticoagulant Heparin-Mimicking Hydrogel Thin Film Attached Substrate Surfaces to Improve Hemocompatibility
Macromolecular Bioscience - Tập 17 Số 2 - Trang 1600281 - 2017
The Effect of Ligand Mobility on the Cellular Interaction of Multivalent Nanoparticles
Macromolecular Bioscience - Tập 20 Số 4 - 2020
AbstractMultivalent nanoparticle binding to cells can be of picomolar avidity
making such interactions almost as intense as those seen with antibodies.
However, reducing nanoparticle design exclusively to avidity optimization by the
choice of ligand and its surface density does not sufficiently account for
controlling and understanding cell–particle interactions. Cell uptake, for
example, is of pa...
Significant Role of Bacterial Undecaprenyl Diphosphate (C55‐UPP) for Rubber Synthesis by Hevea Latex Enzymes
Macromolecular Bioscience - Tập 4 Số 11 - Trang 1039-1052 - 2004
AbstractSummary: Washed bottom fraction (BF) membrane‐bound particles of
centrifuged fresh Hevea latex were found to be very active in rubber
biosynthesis (RB). The washed BF membrane (WBM) showed higher RB activity and is
strongly stimulated by anionic surfactants – more by DOC than SDS. WBM enzymes
system can synthesize rubber either with allylic isoprenes (higher RB) or
without (lower RB). Wash...
Present and Future Role of Chitin and Chitosan in Food
Macromolecular Bioscience - Tập 3 Số 10 - Trang 521-530 - 2003
AbstractThe conversion of processed discarded material into valuable by‐products
and alternative specialty materials has been identified as a timely challenge
for food research and development associated with numerous applications of
chitinous products. Chitin, chitosan, calcareous chitin, and chitosan,
N‐acetylated chitosan, N‐methylene phosphonic chitosan (NMPC), and
N‐lauryl‐N‐methylene phospho...
Plasma Surface Modification of Chitosan Membranes: Characterization and Preliminary Cell Response Studies
Macromolecular Bioscience - Tập 8 Số 6 - Trang 568-576 - 2008
AbstractSurface modification of biomaterials is a way to tailor cell responses
whilst retaining the bulk properties. In this work, chitosan membranes were
prepared by solvent casting and treated with nitrogen or argon plasma at 20 W
for 10–40 min. AFM indicated an increase in the surface roughness as a result of
the ongoing etching process. XPS and contact angle measurements showed different
surfa...
Tubule Nanoclay‐Organic Heterostructures for Biomedical Applications
Macromolecular Bioscience - Tập 19 Số 4 - 2019
AbstractNatural halloysite nanotubes (HNTs) show unique hollow structure, high
aspect ratio and adsorption ability, good biocompatibility, and low toxicity,
which allow for various biomedical applications in the diagnosis and treatment
of diseases. Here, advances in self‐assembly of halloysite for cell capturing
and bacterial proliferation, coating on biological surfaces and related drug
delivery,...
Polymer Alloys of Nodax Copolymers and Poly(lactic acid)
Macromolecular Bioscience - Tập 4 Số 3 - Trang 269-275 - 2004
AbstractSummary: Properties of polymer alloys comprising poly(lactic acid) and
Nodax copolymers are investigated. Nodax is a family of bacterially produced
polyhydroxyalkanoate (PHA) copolymers comprising 3‐hydroxybutyrate (3HB) and
other 3‐hydroxyalkanoate (3HA) units with side groups greater than or equal to
three carbon units. The incorporation of 3HA units with medium‐chain‐length
(mcl) side g...
Covalent Growth Factor Immobilization Strategies for Tissue Repair and Regeneration
Macromolecular Bioscience - Tập 11 Số 9 - Trang 1149-1163 - 2011
AbstractGrowth factors play a critical role in regulating processes involved in
cellular differentiation and tissue regeneration, and are therefore considered
essential elements in many tissue engineering strategies. The covalent
immobilization of growth factors to biomaterial matrices addresses many of the
challenges associated with delivering freely‐diffusible growth factors and has
thus emerged...
Tổng số: 62
- 1
- 2
- 3
- 4
- 5
- 6
- 7