Macromolecular Bioscience

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Mitogenic Activity of Sulfated Chitosan and Cellulose Derivatives is Related to Protection of FGF‐2 from Proteolytic Cleavage
Macromolecular Bioscience - Tập 12 Số 6 - Trang 740-750 - 2012
Annett Weltrowski, Sidalina Almeida, Dieter Peschel, Kai Zhang, Steffen Fischer, Thomas Groth
AbstractNovel chitosan (CHS) and cellulose sulfates (CSs) are studied regarding their mitogenic activity and their protective effect against proteolytic digestion of FGF‐2. An intermediate degree of sulfation (DSS) and lower concentration of CHS have superior effect on 3T3 cell growth while the mitogenic activity of CS increases with DS... hiện toàn bộ
Super-Anticoagulant Heparin-Mimicking Hydrogel Thin Film Attached Substrate Surfaces to Improve Hemocompatibility
Macromolecular Bioscience - Tập 17 Số 2 - Trang 1600281 - 2017
Min He, Xiaofei Cui, Huiyi Jiang, Xuelian Huang, Weifeng Zhao, Changsheng Zhao
Plasma Surface Modification of Chitosan Membranes: Characterization and Preliminary Cell Response Studies
Macromolecular Bioscience - Tập 8 Số 6 - Trang 568-576 - 2008
Simone S. Silva, Sandra M. Luna, Manuela E. Gomes, J. Benesch, Iva Pashkuleva, João F. Mano, Rui L. Reis
AbstractSurface modification of biomaterials is a way to tailor cell responses whilst retaining the bulk properties. In this work, chitosan membranes were prepared by solvent casting and treated with nitrogen or argon plasma at 20 W for 10–40 min. AFM indicated an increase in the surface roughness as a result of the ongoing etching process. XPS and contact angle me...... hiện toàn bộ
Covalent Growth Factor Immobilization Strategies for Tissue Repair and Regeneration
Macromolecular Bioscience - Tập 11 Số 9 - Trang 1149-1163 - 2011
Kristyn S. Masters
AbstractGrowth factors play a critical role in regulating processes involved in cellular differentiation and tissue regeneration, and are therefore considered essential elements in many tissue engineering strategies. The covalent immobilization of growth factors to biomaterial matrices addresses many of the challenges associated with delivering freely‐diffusible gr...... hiện toàn bộ
Electrospun Gelatin Fibers with a Multiple Release of Antibiotics Accelerate Dermal Regeneration in Infected Deep Burns
Macromolecular Bioscience - Tập 16 Số 9 - Trang 1368-1380 - 2016
Jianmei Chen, Zongguang Liu, Maohua Chen, Hong Zhang, Xiaohong Li
Electrospun fibers of hydrophilic polymers meet challenges in a rapid degradation of fiber matrices and discharge of antibiotics to comply with requirements of infection control as a dermal regeneration template. In the current study, a pH conversion process is initially developed to ensure fluent electrospinning, an efficient in situ cross‐linking of electrospun gelatin fibers with oxidiz...... hiện toàn bộ
Self‐Association of Unfolded Outer Membrane Proteins
Macromolecular Bioscience - Tập 10 Số 7 - Trang 763-767 - 2010
Alexandra Ebie Tan, N. K. Burgess, Diana S. DeAndrade, Jacob D. Marold, Karen G. Fleming
AbstractWe have investigated self‐association propensities of aqueous unfolded (UAQ) forms of eight outer membrane proteins (OMPs), OmpA, OmpW, OmpX, PagP, OmpT, OmpLa, FadL, and Omp85. We found that high urea concentrations maintain all of these OMPs as monomers and that OmpA and OmpX remain monomeric upon dilution to 1 M ur...... hiện toàn bộ
Effect of Hydration on Silk Film Material Properties
Macromolecular Bioscience - Tập 10 Số 4 - Trang 393-403 - 2010
Brian D. Lawrence, Scott E. Wharram, Jonathan A. Kluge, Gary G. Leisk, Fiorenzo G. Omenetto, Mark I. Rosenblatt, David L. Kaplan
AbstractEffects of hydration on silk fibroin film properties were investigated for water‐annealed and MeOH‐treated samples. Hydration increased thickness by 60% for MeOH‐immersed films, while water‐annealed samples remained constant. MeOH‐immersed films showed an 80% mass loss due to water, while water‐annealed lost only 40%. O2 permeability wa...... hiện toàn bộ
Characterization of Methyl Methacrylate Grafting onto Preirradiated Biodegradable Lignocellulose Fiber by γ‐Radiation
Macromolecular Bioscience - Tập 5 Số 1 - Trang 78-89 - 2005
Ferdous Khan
AbstractSummary: Gamma‐radiation‐induced graft copolymerization of methyl methacrylate onto natural lignocellulose (jute) fiber was carried out by the preirradiation method in an aqueous medium by using octylphenoxy‐polyethoxyethanol as an emulsifier. The different factors that influenced the graft copolymer reaction process were investigated...... hiện toàn bộ
Template‐Directed Control of Crystal Morphologies
Macromolecular Bioscience - Tập 7 Số 2 - Trang 152-162 - 2007
Fiona C. Meldrum, Sabine Ludwigs
AbstractBiominerals are characterised by unique morphologies, and it is a long‐term synthetic goal to reproduce these synthetically. We here apply a range of templating routes to investigate whether a fascinating category of biominerals, the single crystals with complex forms, can be produced using simple synthetic methods. Macroporous crystals with sponge‐like mor...... hiện toàn bộ
Multifunctional Hybrid Three‐dimensionally Woven Scaffolds for Cartilage Tissue Engineering
Macromolecular Bioscience - Tập 10 Số 11 - Trang 1355-1364 - 2010
Franklin T. Moutos, Bradley T. Estes, Farshid Guilak
AbstractThe successful replacement of large‐scale cartilage defects or osteoarthritic lesions using tissue‐engineering approaches will likely require composite biomaterial scaffolds that have biomimetic mechanical properties and can provide cell‐instructive cues to control the growth and differentiation of embedded stem or progenitor cells. This study describes a n...... hiện toàn bộ
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