Journal of the Royal Society Interface
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Control of human gait stability through foot placementDuring human walking, the centre of mass (CoM) is outside the base of support for most of the time, which poses a challenge to stabilizing the gait pattern. Nevertheless, most of us are able to walk without substantial problems. In this review, we aim to provide an integrative overview of how humans cope with an underactuated gait pattern. A central idea that emerges from the literature is... ...
Journal of the Royal Society Interface - Tập 15 Số 143 - Trang 20170816 - 2018
Distributed robustness in cellular networks: insights from synthetic evolved circuitsEvolved natural systems are known to display some sort of distributed robustness against the loss of individual components. Such type of robustness is not just the result of redundancy. Instead, it seems to be based on degeneracy, i.e. the ability of elements that are structurally different to perform the same function or yield the same output. Here, we explore the problem of how relevant ... ...
Journal of the Royal Society Interface - Tập 6 Số 33 - Trang 393-400 - 2009
Nano-sized manganese oxides as biomimetic catalysts for water oxidation in artificial photosynthesis: a reviewThere has been a tremendous surge in research on the synthesis of various metal compounds aimed at simulating the water-oxidizing complex (WOC) of photosystem II (PSII). This is crucial because the water oxidation half reaction is overwhelmingly rate-limiting and needs high over-voltage (approx. 1 V), which results in low conversion efficiencies when working at current densities required f... ...
Journal of the Royal Society Interface - Tập 9 Số 75 - Trang 2383-2395 - 2012
Challenges in tissue engineeringAlmost 30 years have passed since a term ‘tissue engineering’ was created to represent a new concept that focuses on regeneration of neotissues from cells with the support of biomaterials and growth factors. This interdisciplinary engineering has attracted much attention as a new therapeutic means that may overcome the drawbacks involved in the current artificial organs and organ transplan... ...
Journal of the Royal Society Interface - Tập 3 Số 10 - Trang 589-601 - 2006
Exit rights open complex pathways to cooperationWe study the evolutionary dynamics of the Prisoner’s Dilemma game in which cooperators and defectors interact with another actor type called exiters. Rather than being exploited by defectors, exiters exit the game in favour of a small pay-off. We find that this simple extension of the game allows cooperation to flourish in well-mixed populations when iterations or reputation are added. In ... ...
Journal of the Royal Society Interface - Tập 18 Số 174 - Trang 20200777 - 2021
Landscape epidemiology of plant diseasesMany agricultural landscapes are characterized by a high degree of heterogeneity and fragmentation. Landscape ecology focuses on the influence of habitat heterogeneity in space and time on ecological processes. Landscape epidemiology aims at applying concepts and approaches originating from landscape ecology to the study of pathogen dynamics at the landscape scale. However, despite the str... ...
Journal of the Royal Society Interface - Tập 4 Số 16 - Trang 963-972 - 2007
Comparison of spatial interpolation methods to create high-resolution poverty maps for low- and middle-income countriesHigh-resolution poverty maps are important tools for promoting equitable and sustainable development. In settings without data at every location, we can use spatial interpolation (SI) to create such maps using sample-based surveys and additional covariates. In the model-based geostatistics (MBG) framework for SI, it is typically assumed that the similarity of two areas is inversely related... ...
Journal of the Royal Society Interface - Tập 15 Số 147 - Trang 20180252 - 2018
How receptor diffusion influences gradient sensingChemotaxis, or directed motion in chemical gradients, is critical for various biological processes. Many eukaryotic cells perform spatial sensing, i.e. they detect gradients by comparing spatial differences in binding occupancy of chemosensory receptors across their membrane. In many theoretical models of spatial sensing, it is assumed, for the sake of simplicity, that the receptors concer... ...
Journal of the Royal Society Interface - Tập 12 Số 102 - Trang 20141097 - 2015
Substrate-induced phenotypic switches of human smooth muscle cells: anin vitrostudy of in-stent restenosis activation pathwaysIn-stent restenosis is a clinical complication following coronary angioplasty caused by the implantation of the metal device in the atherosclerotic vessel. Histological examination has shown a clear contribution of both inflammatory and smooth muscle cells (SMCs) to the deposition of an excess of neointimal tissue. However, the sequence of events leading to clinically relevant restenosis i... ...
Journal of the Royal Society Interface - Tập 8 Số 58 - Trang 641-649 - 2011
Genome and proteome annotation: organization, interpretation and integrationRecent years have seen a huge increase in the generation of genomic and proteomic data. This has been due to improvements in current biological methodologies, the development of new experimental techniques and the use of computers as support tools. All these raw data are useless if they cannot be properly analysed, annotated, stored and displayed. Consequently, a vast number of resources h... ...
Journal of the Royal Society Interface - Tập 6 Số 31 - Trang 129-147 - 2009
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