In 3D sinh học của cấu trúc van động mạch chủ không đồng nhất bằng hydrogels alginate/gelatin Dịch bởi AI Tập 101A Số 5 - Trang 1255-1264 - 2013
Bin Duan, Laura A. Hockaday, Kevin H. Kang, Jonathan T. Butcher
Tóm tắtBệnh van tim là một vấn đề sức khỏe cộng đồng nghiêm trọng và ngày càng
gia tăng, trong đó việc thay thế bằng bộ phận giả là điều thường thấy. Các thiết
bị giả hiện tại không đủ tốt cho người lớn trẻ tuổi và trẻ em đang phát triển.
Các kênh van động mạch chủ sống được thiết kế mô có tiềm năng để tái cấu trúc,
tái tạo, và phát triển, nhưng việc chế tạo độ phức tạp giải phẫu tự nhiên với
tính... hiện toàn bộ
#bệnh van tim #van động mạch chủ #sinh học in 3D #alginate/gelatin #công nghệ sinh học #tế bào cơ trơn xoang động mạch #tế bào mô liên kết nắp van #kênh van động mạch #vật liệu sinh học
Surface chemistry modulates fibronectin conformation and directs integrin binding and specificity to control cell adhesion Tập 66A Số 2 - Trang 247-259 - 2003
Benjamin G. Keselowsky, David M. Collard, Andrés J. Garcı́a
AbstractIntegrin‐mediated cell adhesion to proteins adsorbed onto synthetic
surfaces anchors cells and triggers signals that direct cell function. In the
case of fibronectin (Fn), adsorption onto substrates of varying properties
alters its conformation/structure and its ability to support cell adhesion. In
the present study, self‐assembled monolayers (SAMs) of alkanethiols on gold were
used as mod... hiện toàn bộ
High surface energy enhances cell response to titanium substrate microstructure Tập 74A Số 1 - Trang 49-58 - 2005
Gang Zhao, Zvi Schwartz, Marco Wieland, Frank Rupp, Jürgen Geis‐Gerstorfer, David L. Cochran, Barbara D. Boyan
AbstractTitanium (Ti) is used for implantable devices because of its
biocompatible oxide surface layer. TiO2 surfaces that have a complex
microtopography increase bone‐to‐implant contact and removal torque forces in
vivo and induce osteoblast differentiation in vitro. Studies examining
osteoblast response to controlled surface chemistries indicate that hydrophilic
surfaces are osteogenic, but TiO2... hiện toàn bộ
Nano‐fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment Tập 67A Số 2 - Trang 531-537 - 2003
Kyung Mi Woo, Victor J. Chen, X. Peter
AbstractTissue engineering aims at resolving problems such as donor shortage and
immune rejection faced by transplantation. Scaffolds (artificial extracellular
matrices) have critical roles in tissue engineering. Recently, we developed
nano‐fibrous poly(L‐lactic acid) scaffolds under the hypothesis that synthetic
nano‐fibrous scaffolding, mimicking the structure of natural collagen fibers,
could c... hiện toàn bộ
Evaluation of hydrogels for bio‐printing applications Tập 101A Số 1 - Trang 272-284 - 2013
Sean V. Murphy, Aleksander Skardal, Anthony Atala
AbstractIn the United States alone, there are approximately 500,000 burn
injuries that require medical treatment every year. Limitations of current
treatments necessitate the development of new methods that can be applied
quicker, result in faster wound regeneration, and yield skin that is
cosmetically similar to undamaged skin. The development of new hydrogel
biomaterials and bioprinting depositi... hiện toàn bộ
Synthesis and characterization of biocompatible Fe3O4 nanoparticles Tập 80A Số 2 - Trang 333-341 - 2007
Jing Sun, Shaobing Zhou, Peng Hou, Xinyi Li, Jie Weng, Xiaohong Li, Mingyuan Li
AbstractIn this study, magnetite (Fe3O4) nanoparticles with a size range of 8–20
nm were prepared by the modified controlled chemical coprecipitation method from
the solution of ferrous/ferric mixed salt‐solution in alkaline medium. In the
process, two kinds of surfactant (sodium oleate and polyethylene glycol) were
studied; then, sodium oleate was chosen as the apt surfactant to attain
ultrafine,... hiện toàn bộ
Significantly accelerated osteoblast cell growth on aligned TiO2 nanotubes Tập 78A Số 1 - Trang 97-103 - 2006
Seunghan Oh, Chiara Daraio, L.-H. Chen, Thomas R. Pisanic, Rita Fiñones, Sungho Jin
AbstractVertically aligned yet laterally spaced nanoscale TiO2 nanotubes have
been grown on Ti by anodization, and the growth of MC3T3‐E1 osteoblast cells on
such nanotubes has been investigated. The adhesion/propagation of the osteoblast
is substantially improved by the topography of the TiO2 nanotubes with the
filopodia of growing cells actually going into the nanotube pores, producing an
interl... hiện toàn bộ
Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications Tập 93A Số 4 - Trang 1539-1550 - 2010
Sambit Sahoo, Lay Teng Ang, James Cho‐Hong Goh, Siew‐Lok Toh
AbstractTissue engineering scaffolds should ideally mimic the natural ECM in
structure and function. Electrospun nanofibrous scaffolds are easily fabricated
and possess a biomimetic nanostructure. Scaffolds can mimic ECM function by
acting as a depot for sustained release of growth factors. bFGF, an important
growth factor involved in tissue repair and mesenchymal stem cell proliferation
and diffe... hiện toàn bộ
Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus Tập 66A Số 3 - Trang 605-614 - 2003
Darren S. Gray, Joe Tien, Christopher S. Chen
AbstractAdherent cells are strongly influenced by the mechanical aspects of
biomaterials, but little is known about the cellular effects of spatial
variations in these properties. This work describes a novel method to produce
polymeric cell culture surfaces containing micrometer‐scale regions of variable
stiffness. Substrates made of acrylamide or poly(dimethylsiloxane) were
patterned with 100‐ or... hiện toàn bộ