International Journal of Developmental Neuroscience

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Stimulation of neurite outgrowth in vitro by a glycero‐ganglioside
International Journal of Developmental Neuroscience - Tập 6 - Trang 319-326 - 1988
Michael S. Cannella, Aureliu J. Acher, Robert W. Ledeen
AbstractA glycerol‐containing analog of ganglioside, with sialic acid attached to a diglyceride‐like structure possessing two ether‐linked alkyl chains, was prepared synthetically and applied exogenously to three culture systems; neuro‐2A neuroblastoma cells, PC12 cells and dorsal root ganglia. This resulted in pronounced stimulation of neun...... hiện toàn bộ
High plasma neopterin levels in Chinese children with autism spectrum disorders
International Journal of Developmental Neuroscience - Tập 41 - Trang 92-97 - 2015
Hong-xiang Zhao, Sha-sha Yin, Jin-gang Fan
AbstractBackgroundNeopterin, a pteridine mainly synthesized by activated macrophages, is a marker of inflammation, immune system activation and an active participant in Autism spectrum disorders (ASD). The aim of this study was to assess the clinical significance of plasma neopterin levels in ASD.... hiện toàn bộ
Phản ứng in vitro khác nhau đối với rIL‐1β của tế bào thái dương não chuột con và chuột trưởng thành Dịch bởi AI
International Journal of Developmental Neuroscience - Tập 9 - Trang 501-507 - 1991
M. Colasanti, Maria T. Ramacci, Piero Foresta, Giuliana M. Lauro
Tóm tắtTrong tài liệu gần đây, các lymphokine đã được báo cáo có khả năng thúc đẩy cả sự phát triển và trưởng thành của một số quần thể thần kinh đệm. Trong bài viết này, chúng tôi so sánh hiệu ứng của rIL-1 trên tế bào thần kinh đệm của chuột con và chuột trưởng thành in vitro. Ở chuột con, nhưng không ở tế bào th...... hiện toàn bộ
Restricted growth and insulin‐like growth factor‐1 deficiency in mice lacking presenilin‐1 in the neural crest cell lineage
International Journal of Developmental Neuroscience - Tập 27 - Trang 837-843 - 2009
Mitsunari Nakajima, Sono Watanabe, Satoshi Okuyama, Jie Shen, Yoshiko Furukawa
AbstractPresenilin‐1 (PS1) is a transmembrane protein that is in many cases responsible for the development of early‐onset familial Alzheimer's disease. PS1 is essential for neurogenesis, somitogenesis, angiogenesis, and cardiac morphogenesis. We report here that PS1 is also required for maturation and/or maintenance of the pituitary gland. We generated PS1‐conditi...... hiện toàn bộ
Emerging roles for TGF‐β1 in nervous system development
International Journal of Developmental Neuroscience - Tập 23 - Trang 413-424 - 2005
Flávia Carvalho Alcantara Gomes, Vivian de Oliveira Sousa, Luciana Romão
AbstractTransforming growth factor betas (TGF‐βs) are known as multifunctional growth factors, which participate in the regulation of key events of development, disease and tissue repair. In central nervous system (CNS), TGF‐β1 has been widely recognized as an injury‐related cytokine, specially associated with astrocyte scar formation in response to brain injury. T...... hiện toàn bộ
Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring
International Journal of Developmental Neuroscience - Tập 27 - Trang 525-530 - 2009
Vera Bubenikova-Valesova, Petr Kacer, Kamila Syslova, Lukas Rambousek, Martin Janovsky, Barbora Schutova, Lenka Hruba, Romana Slamberova
AbstractMethamphetamine is a commonly abused psychostimulant that causes addiction and is often abused by pregnant women. Acute or chronic administration of methamphetamine elevates the levels of the extracellular monoamine neurotransmitters, such as dopamine.The aim of the present study was to show whether prenatal exposure to methamphetamine (5 m...... hiện toàn bộ
Age‐ and region‐dependent patterns of Ca2+ accumulations following status epilepticus
International Journal of Developmental Neuroscience - Tập 26 - Trang 779-790 - 2008
Linda K. Friedman, Aleksandr Saghyan, Alex Peinado, Robert Keesey
AbstractElevated Ca2+ concentrations have been implicated in cell death mechanisms following seizures, however, the age and brain region of intracellular Ca2+ accumulations [Ca2+]i, may influence whether or not they are toxic. Therefore, we examined regional ...... hiện toàn bộ
Anti‐apoptotic role of omega‐3‐fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model
International Journal of Developmental Neuroscience - Tập 27 - Trang 377-383 - 2009
Rohit A. Sinha, Priyanka Khare, Asit Rai, Shailendra Kumar Maurya, Amrita Pathak, Vishwa Mohan, Geet Kumar Nagar, Mohana Krishna Reddy Mudiam, Madan M. Godbole, Sanghamitra Bandyopadhyay
AbstractInadequate maternal intake of omega‐3‐fatty acids (ω3 FAs) causes adverse neurodevelopmental outcome in the progeny; however, their molecular mechanism of action is obscure. Since ω3 FAs are known to inhibit neuronal apoptosis during neuro‐degeneration, we investigated their possible contribution in regulating neuronal apoptosis during brain development. Us...... hiện toàn bộ
Role of glucocorticoids in the chromaffin‐neuron developmental decision
International Journal of Developmental Neuroscience - Tập 7 - Trang 475-483 - 1989
David J Anderson, Arie Michelsohn
AbstractChromaffin cells and sympathetic neurons develop from a common neural crest‐derived progenitor cell. The developmental fate of this cell differs depending upon whether it migrates to the sympathetic ganglion or to the adrenal gland primordium, suggesting that local environmental signals control its differentiation. Glucocorticoid (GC...... hiện toàn bộ
Developmental profiles of ornithine decarboxylase activity in the hippocampus, neocortex and cerebellum: Modulation following lead exposure
International Journal of Developmental Neuroscience - Tập 12 Số 1 - Trang 25-30 - 1994
Nasser H. Zawia, L. B. Evers, G. Jean Harry
AbstractOrnithine decarboxylase (ODC) is a growth‐associated enzyme which is critical for cell growth and transformation. ODC activity follows a specific ontogenetic pattern of activity in distinct brain regions according to their developmental stage. Perturbations in the pattern of ODC activity have been associated with brain damage includi...... hiện toàn bộ
Tổng số: 1,357   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10