Human Psychopharmacology
SCIE-ISI SCOPUS (1986-2023)
1099-1077
0885-6222
Anh Quốc
Cơ quản chủ quản: WILEY , John Wiley and Sons Ltd
Lĩnh vực:
Neurology (clinical)Psychiatry and Mental HealthPharmacology (medical)Neurology
Các bài báo tiêu biểu
Circadian rhythm disturbances in depressionAbstract Objective The aim of this article is to review progress in understanding the mechanisms that underlie circadian and sleep rhythms, and their role in the pathogenesis and treatment of depression. Methods Literature was selected principally by Medline searches, and ...
Tập 23 Số 7 - Trang 571-585 - 2008
Drug induced nightmares—an etiology based reviewAbstract Objective Recent clinical trials have included patient complaints of nightmares as a category of reportable medication side effects. This study integrates that data into current experimental and theoretical research of drug effects that may alter dreaming and nightmares. The objective is to provide a clinical and theoretica...
Tập 18 Số 1 - Trang 59-67 - 2003
Comparing the efficacy and safety ofCrocus sativusL. with memantine in patients with moderate to severe Alzheimer's disease: a double-blind randomized clinical trial
Tập 29 Số 4 - Trang 351-359 - 2014
Saffron for treatment of fluoxetine‐induced sexual dysfunction in women: randomized double‐blind placebo‐controlled studyObjective Saffron (Crocus sativus L.) has shown beneficial aphrodisiac effects in some animal and human studies. The aim of the present study was to assess the safety and efficacy of saffron on selective serotonin reuptake inhibitor‐induced sexual dysfunction in women. Methods ...
Tập 28 Số 1 - Trang 54-60 - 2013
An investigation of the range of cognitive impairments induced by scopolamine 0·6 mg s.cAbstract The present study was conducted to determine the degree to which impairments in attention accompany the memory deficits produced by scopolamine. Eighteen healthy young volunteers received scopolamine 0·6 mg subcutaneously on three experimental sessions and placebo on three others. On each session, prior to, and 60 min after injection, the subjects underwent... ...
Tập 3 Số 1 - Trang 27-41 - 1988
A method for determining the magnitude of change across different cognitive functions in clinical trials: the effects of acute administration of two different doses alprazolamAbstract While there is no doubt that benzodiazepine administration leads to transient cognitive impairment in healthy adults, the nature and magnitude of such impairment has not been well described. The cognitive effects of a single dose of alprazolam 0.5 and 1 mg were therefore assessed in 36 healthy adults on measures of psychomotor function, visual attention, wo... ...
Tập 20 Số 4 - Trang 263-273 - 2005
A pilot trial of quetiapine for the treatment of patients with deliriumAbstract Twenty‐two Korean inpatients with delirium were administered prospectively a flexible dose of quetiapine. The delirium rating scale‐revised‐severity 98 (DRS‐R‐98) and clinical global impression scale‐severity (CGI‐s) scores were assessed at the time of pre‐ and post‐treatment. The DRS‐R‐98 and CGI‐s scores were significantly reduced by 57.3% and 55.1%, resp... ...
Tập 19 Số 2 - Trang 125-127 - 2004
A comparative study of on‐the‐road and simulated driving performance after nocturnal treatment with lormetazepam 1 mg and oxazepam 50 mgAbstract The main purpose of this study was to compare the sensitivity of a driving simulator test model (TS2) with a standard on‐the‐road driving test, after one night treatment with lormetazepam 1 mg, oxazepam 50 mg (as a verum) and placebo. The secondary purpose was to measure the effects of the intended drugs and placebo in the same subject sample, after two tre... ...
Tập 7 Số 5 - Trang 297-309 - 1992
Development of a statistical approach to classifying treatment response in individual children with ADHDAbstract The use of cognitive tests as measures of treatment response in individual children with ADHD has not been adequately evaluated or commonly applied by clinicians. This is most likely due to a lack of suitable assessment tasks as well as clinicians' limited awareness of the appropriate statistical techniques for analysing cognitive change in individuals. Thi... ...
Tập 19 Số 7 - Trang 445-456 - 2004
Stability of cognitive impairment in chronic schizophrenia over brief and intermediate re‐test intervalsAbstract Objective This study examined between‐ and within‐subject stability of cognitive performance in individuals with chronic schizophrenia. Methods Thirty individuals with schizophrenia and 20 healthy controls matched by age, sex, education, and estimated IQ underwent...
Tập 24 Số 2 - Trang 113-121 - 2009