Human Psychopharmacology
SCIE-ISI SCOPUS (1986-2025)
1099-1077
0885-6222
Anh Quốc
Cơ quản chủ quản: WILEY , John Wiley and Sons Ltd
Lĩnh vực:
Neurology (clinical)Psychiatry and Mental HealthPharmacology (medical)Neurology
Các bài báo tiêu biểu
Circadian rhythm disturbances in depression
Tập 23 Số 7 - Trang 571-585 - 2008
AbstractObjectiveThe aim of this article is to review progress in understanding
the mechanisms that underlie circadian and sleep rhythms, and their role in the
pathogenesis and treatment of depression.MethodsLiterature was selected
principally by Medline searches, and additional reports were identified based on
ongoing research activities in the authors' laboratory.ResultsMany physiological
proces...
Drug induced nightmares—an etiology based review
Tập 18 Số 1 - Trang 59-67 - 2003
AbstractObjectiveRecent clinical trials have included patient complaints of
nightmares as a category of reportable medication side effects. This study
integrates that data into current experimental and theoretical research of drug
effects that may alter dreaming and nightmares. The objective is to provide a
clinical and theoretical framework useful in categorizing the potential and
reported drug e...
Comparing the efficacy and safety ofCrocus sativusL. with memantine in patients with moderate to severe Alzheimer's disease: a double-blind randomized clinical trial
Tập 29 Số 4 - Trang 351-359 - 2014
Saffron for treatment of fluoxetine‐induced sexual dysfunction in women: randomized double‐blind placebo‐controlled study
Tập 28 Số 1 - Trang 54-60 - 2013
ObjectiveSaffron (Crocus sativus L.) has shown beneficial aphrodisiac effects in
some animal and human studies. The aim of the present study was to assess the
safety and efficacy of saffron on selective serotonin reuptake inhibitor‐induced
sexual dysfunction in women.MethodsThis was a randomized double‐blind
placebo‐controlled study. Thirty‐eight women with major depression who were
stabilized on ...
An investigation of the range of cognitive impairments induced by scopolamine 0·6 mg s.c
Tập 3 Số 1 - Trang 27-41 - 1988
AbstractThe present study was conducted to determine the degree to which
impairments in attention accompany the memory deficits produced by scopolamine.
Eighteen healthy young volunteers received scopolamine 0·6 mg subcutaneously on
three experimental sessions and placebo on three others. On each session, prior
to, and 60 min after injection, the subjects underwent an automated computerized
batter...
A method for determining the magnitude of change across different cognitive functions in clinical trials: the effects of acute administration of two different doses alprazolam
Tập 20 Số 4 - Trang 263-273 - 2005
AbstractWhile there is no doubt that benzodiazepine administration leads to
transient cognitive impairment in healthy adults, the nature and magnitude of
such impairment has not been well described. The cognitive effects of a single
dose of alprazolam 0.5 and 1 mg were therefore assessed in 36 healthy adults on
measures of psychomotor function, visual attention, working memory, planning and
learni...
A pilot trial of quetiapine for the treatment of patients with delirium
Tập 19 Số 2 - Trang 125-127 - 2004
AbstractTwenty‐two Korean inpatients with delirium were administered
prospectively a flexible dose of quetiapine. The delirium rating
scale‐revised‐severity 98 (DRS‐R‐98) and clinical global impression
scale‐severity (CGI‐s) scores were assessed at the time of pre‐ and
post‐treatment. The DRS‐R‐98 and CGI‐s scores were significantly reduced by
57.3% and 55.1%, respectively. Quetiapine was effectiv...
A comparative study of on‐the‐road and simulated driving performance after nocturnal treatment with lormetazepam 1 mg and oxazepam 50 mg
Tập 7 Số 5 - Trang 297-309 - 1992
AbstractThe main purpose of this study was to compare the sensitivity of a
driving simulator test model (TS2) with a standard on‐the‐road driving test,
after one night treatment with lormetazepam 1 mg, oxazepam 50 mg (as a verum)
and placebo. The secondary purpose was to measure the effects of the intended
drugs and placebo in the same subject sample, after two treatment nights in the
morning and ...
Development of a statistical approach to classifying treatment response in individual children with ADHD
Tập 19 Số 7 - Trang 445-456 - 2004
AbstractThe use of cognitive tests as measures of treatment response in
individual children with ADHD has not been adequately evaluated or commonly
applied by clinicians. This is most likely due to a lack of suitable assessment
tasks as well as clinicians' limited awareness of the appropriate statistical
techniques for analysing cognitive change in individuals. This study
investigated the applicat...
Stability of cognitive impairment in chronic schizophrenia over brief and intermediate re‐test intervals
Tập 24 Số 2 - Trang 113-121 - 2009
AbstractObjectiveThis study examined between‐ and within‐subject stability of
cognitive performance in individuals with chronic schizophrenia.MethodsThirty
individuals with schizophrenia and 20 healthy controls matched by age, sex,
education, and estimated IQ underwent repeated cognitive assessments at baseline
and 30 days using computerized tests of psychomotor function, visual
attention/informat...