Future Journal of Pharmaceutical Sciences
ESCI-ISI
2314-7253
Cơ quản chủ quản: SPRINGER
Lĩnh vực:
Pharmacology & Pharmacy
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Flavonoids as natural phenolic compounds and their role in therapeutics: an overview
Tập 7 Số 1
Abstract Background Natural plants and plant-derived formulations have been used
by mankind from the ancient period of time. For the past few years, many
investigations elaborated the therapeutic potential of various secondary
chemicals present in the plants. Literature revealed that the various secondary
metabolites, viz. phenolics and flavonoids, are responsible for a variety of
therapeutic acti...
A brief review of the biological potential of indole derivatives
Tập 6 Số 1 - 2020
AbstractBackgroundVarious bioactive aromatic compounds containing the indole
nucleus showed clinical and biological applications. Indole scaffold has been
found in many of the important synthetic drug molecules which gave a valuable
idea for treatment and binds with high affinity to the multiple receptors
helpful in developing new useful derivatives.Main textIndole derivatives possess
various biol...
Evaluation of the anti-bacterial activity of methanolic extract of Chlorella vulgaris Beyerinck [Beijerinck] with special reference to antioxidant modulation
Tập 7 Số 1 - 2021
Abstract Background The natural antioxidants from Chlorella have potent
therapeutic implication in several diseases. However, the anti-bacterial
activity and their molecular mode of action have not been investigated yet. The
present study focussed on the assessment of antioxidant potential as well as
free radical scavenging activity such as DPPH, hydroxyl radical, hydrogen
peroxide, and superoxide...
Recent advances in mesalamine colonic delivery systems
Tập 6 Số 1 - 2020
Abstract Background Increased attention has been focused on the continuous
development and improvement of mesalamine colonic specific delivery systems, for
the effective treatment of inflammatory bowel diseases; thus enhancing
therapeutic efficacy and reducing potential side effects. Mesalamine is a class
IV drug, according to the Biopharmaceutics Classification System, used usually
to treat infla...
Smart invasome synthesis, characterizations, pharmaceutical applications, and pharmacokinetic perspective: a review
Tập 6 Số 1 - 2020
Abstract Background Scientists are constantly looking for the introduction of
unique drug delivery systems for the existing drug molecule. Since the skin is
one of the primary and essential organs of the human body, it needs successful
research development for the delivery of the drug. While the skin is assumed a
human body’s multifunctional organ, it has minimal permeability across the
stratum co...
In situ gel drug delivery system for periodontitis: an insight review
Tập 6 Số 1 - 2020
Abstract Background Periodontitis is a microbial disease that leads to
inflammation in the tooth-supporting tissues of the oral cavity that is common
among the elderly. It is initiated by oral inflammation induced by bacterial
dysbiosis. Choosing an appropriate antimicrobial agent with the right course of
drug administration is the key to successful periodontal therapy. In recent
times, with more ...
Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review
Tập 7 Số 1 - 2021
Abstract Background The plant Cochlospermum tinctorium A. Rich is a sub-shrub
that belongs to the family Cochlospermaceae. The plant has been used in
traditional medicine for the treatment of malaria, rickets, stomachache,
diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain,
inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis,
labour, menstrual problem...
2D QSAR, design, docking study and ADMET of some N-aryl derivatives concerning inhibitory activity against Alzheimer disease
Tập 8 - Trang 1-14 - 2022
Alzheimer disease (AD) is an ailment that disturbs mainly people of old age. The
fundamental remedial way to deal with AD depends on the utilization of AChEI.
The design of new intense and particular AChEI is critical in drug discovery. In
silico technique will be used to solve the above problem. A new method was
established to discover novel agents with better biological activity against
Alzheime...
Unveiling novel inhibitors of dopamine transporter via in silico drug design, molecular docking, and bioavailability predictions as potential antischizophrenic agents
Tập 7 Số 1 - 2021
Abstract Background The inhibition of dopamine transporter is known to play a
significant role in the treatment of schizophrenia-related and other mental
disorders. In a continuing from our previous study, computational drug design
approach, molecular docking simulation, and pharmacokinetics study were explored
for the identification of novel inhibitors dopamine transporter as potential
Antischizo...
Design of more potent quinazoline derivatives as EGFRWT inhibitors for the treatment of NSCLC: a computational approach
Tập 7 Số 1 - 2021
Abstract Background Lung cancer remains the leading and deadly type of cancer
worldwide. It was estimated to account for about 25% of the 7 million people
that died as a result of cancer-related issues/mortality every year in the
world. Non-small cell lung cancer (NSCLC) is the lethal/deadly class of lung
cancer with nearly 1.5 million reported cases and less than 20% survival rate.
Therefore, it ...