Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

Future Journal of Pharmaceutical Sciences - Tập 7 Số 1 - 2021
Mubarak Hussaini Ahmad1, Abubakar Ibrahim Jatau2, Garba M. Khalid3, Omar Alshargi4
1Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria
2School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tas, 7005, Australia
3Faculty of Pharmaceutical Sciences, Bayero University, Kano, P.M.B. 3011, Nigeria
4College of Pharmacy, Riyadh Elm University, Qurtoba 11681, Riyadh, Saudi Arabia

Tóm tắt

Abstract Background The plant Cochlospermum tinctorium A. Rich is a sub-shrub that belongs to the family Cochlospermaceae. The plant has been used in traditional medicine for the treatment of malaria, rickets, stomachache, diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain, inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis, labour, menstrual problems, and many other diseases. This review summarizes the traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium. Main text To date, few bioactive molecules have been identified and isolated from the plant such as 7,3-dimethyldihydroquercelin, 5,4-dimethylquercelin, cochloxanthine, dihydrocochloxanthine, arjunolic acid, 3-O-E-p-coumaroylalphitolic acid, alphitolic acid, 1-hydroxytetradecan-3-one, 3-bisabolen, 2-tridecanone, 3-hexadecanone, 1-dodecanol, l-tetradecanol, 2-pentdecanone, 3-octadecanone, 1-hydroxy-3-hexadecanone, 1-nonadecanol, l-O-acetyl-3-hexadecanone, and l-hydroxy-3-oetadecanone. The literature related some of the reported ethnomedicinal uses of the plant to these compounds found in the different parts of the plant. Conclusion The comprehensive information documented in this review about the importance of the C. tinctorium may provide an opportunity for research advancement in drug discovery and a better understanding of the medicinal benefits of the plant.

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Future Journal of Pharmaceutical Sciences

Tập 7 Số 1

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