Future Journal of Pharmaceutical Sciences
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Synthesis and in vitro antimicrobial activity of new steroidal hydrazone derivatives
Future Journal of Pharmaceutical Sciences - Tập 8 - Trang 1-10 - 2022
For many years, various drugs have been used for the treatment of infectious diseases but some bacterial microorganisms have induced resistance to several drugs. In a search of new antimicrobial agents, a series of new steroidal hydrazones were designed and synthesized. The structures of the compounds were established based on the spectral data. The in vitro antimicrobial activity of some newly sy......
Assessment of neonatal intensive care unit nurses’ compliance with standard precautions of infection control and identification of enabling factors
Future Journal of Pharmaceutical Sciences - Tập 9 - Trang 1-13 - 2023
Rigorous implementation of infection prevention and control practices by healthcare workers in different healthcare settings is of utmost importance. Neonates, particularly preterm babies in neonatal intensive care units, are a vulnerable population at high risk for developing nosocomial infections. Nurses have the greatest risk of spreading healthcare-associated infections among patients and heal......
Autoregulation: mediators and renin–angiotensin system in diseases and treatments
Future Journal of Pharmaceutical Sciences - Tập 9 - Trang 1-18 - 2023
Hemodynamic regulation is a substantial part of the physiological integrity of the human body. It is based on the delivery of proper blood perfusion to every organ. Five primary vasoactive substances are nearly located throughout the human body, either released from the endothelium, prostanoids, nitric oxide (NO), and endothelin-1 (ET-1); or considered as hormones, bradykinin (BK) and natriuretic ......
Antioxidant and acetylcholinesterase inhibitory activities, in silico analyses, and anti-Alzheimer’s disease potential of leaf extracts of three Nigerian endemic medicinal plants (Spondias mombin, Carica papaya and Kalanchoe crenata)
Future Journal of Pharmaceutical Sciences - Tập 10 - Trang 1-17 - 2024
The evaluation of the correlations between antioxidant and anti-acetylcholinesterase activities of methanol leaf extracts of three Nigerian endemic plants, Spondias mombin, Carica papaya and Kalanchoe crenata, was carried out. Their constituent phytochemicals were identified by HPLC–DAD fingerprinting. The antioxidant activity as typified by 2,2-diphenyl-1-picrylhydrazyl (DPPH·), 2,2′-azino-bis-(3......
Artemisia vulgaris Linn: an updated review on its multiple biological activities
Future Journal of Pharmaceutical Sciences - Tập 8 - Trang 1-14 - 2022
Artemisia vulgaris Linn, an annual herb, is also known as Mugwort or Wormwood in English, Nagadouna in Hindi, Mashibattiri, or Machipatri in Tamil. Native habitats are temperate Asia, Europe, Northern Africa and Alaska. Ethnomedicinally, it is used in traditional treatments to treat depression, epilepsy, irritability, insomnia and stress. This plant is called Herbaka in the Philippines and is used......
Quantification of organic volatile impurities in Oseltamivir phosphate drug substances by head space gas chromatography
Future Journal of Pharmaceutical Sciences - Tập 8 - Trang 1-13 - 2022
The present work is aimed at quantification of organic volatile solvents like Methanol, Ethanol, Acetonitrile, Isopropyl alcohol (IPA), Dichloromethane (DCM), Methyl tert-butyl ether (MTBE), Hexane fractions, Ethyl acetate (EA), Tetra hydro furan (THF), 1,4-Dioxane, Dimethylformamide (DMF), and Toluene in Oseltamivir phosphate Active pharmaceutical ingredient (API) and pharmaceutical dosage forms.......
Evaluating the prediction power and accuracy of two smart response surface experimental designs after revisiting repaglinide floating tablets
Future Journal of Pharmaceutical Sciences - - 2024
There is a soar in the figure of companies aiming to achieve efficiency in undergoing experimental processes. Therefore, instead of deploying one-factor-at-a-time, design of experiments is becoming rampantly utilized in order to reduce the resources outflow. There are a copious of different smart designs which could be employed as design of experiments tools. Central composite and d-optimal design......
Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
Future Journal of Pharmaceutical Sciences - Tập 8 - Trang 1-20 - 2022
Researchers now have a new avenue to investigate when it comes to miRNA-based therapeutics. miRNAs have the potential to be valuable biomarkers for disease detection. Variations in miRNA levels may be able to predict changes in normal physiological processes. At the epigenetic level, miRNA has been identified as a promising candidate for distinguishing and treating various diseases and defects.
I......
Brentuximab vedotin resistance in classic Hodgkin's lymphoma and its therapeutic strategies: a reviewAbstract
Background
Bone marrow cancer has been at the forefront of cancer research. The propensity of cancers to extravasate to the bone makes it a very relevant topic in the topology of this heterogeneous disease. Our narrative review article addresses Brentuximab vedotin (BV) resistance in classi... ...
Future Journal of Pharmaceutical Sciences -
Pharmacokinetics of nanoparticles: current knowledge, future directions and its implications in drug delivery
Future Journal of Pharmaceutical Sciences - Tập 9 - Trang 1-26 - 2023
Nanoparticles have emerged as a viable biological candidate with the possibility to be employed as drug carriers. They acquire high surface-to-volume ratios and unique physicochemical features such as biochemical, magnetic, optical, and electrical changes at the cellular, atomic, and molecular levels. This phenomenon has proven extensive utility for biomedical applications, as their biological act......
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