Frontiers in Molecular Biosciences
SCOPUS (2014-2023)SCIE-ISI
2296-889X
Thụy Sĩ
Cơ quản chủ quản: Frontiers Media S.A.
Lĩnh vực:
Biochemistry, Genetics and Molecular Biology (miscellaneous)BiochemistryMolecular Biology
Các bài báo tiêu biểu
Solvent Accessibility of Residues Undergoing Pathogenic Variations in Humans: From Protein Structures to Protein SequencesSolvent accessibility (SASA) is a key feature of proteins for determining their folding and stability. SASA is computed from protein structures with different algorithms, and from protein sequences with machine-learning based approaches trained on solved structures. Here we ask the question as to which extent solvent exposure of residues can be associated to the pathogenicity of the variat... ...
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Molecular Mechanisms Behind Anti SARS-CoV-2 Action of LactoferrinDespite the huge effort to contain the infection, the novel SARS-CoV-2 coronavirus has rapidly become pandemic, mainly due to its extremely high human-to-human transmission capability, and a surprisingly high viral charge of symptom-less people. While the seek for a vaccine is still ongoing, promising results have been obtained with antiviral compounds. In particular, lactoferrin is regard... ...
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Non-lysine ubiquitylation: Doing things differentlyThe post-translational modification of proteins with ubiquitin plays a central role in nearly all aspects of eukaryotic biology. Historically, studies have focused on the conjugation of ubiquitin to lysine residues in substrates, but it is now clear that ubiquitylation can also occur on cysteine, serine, and threonine residues, as well as on the N-terminal amino group of proteins. Paradigm... ...
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Adhesions Assemble!—Autoinhibition as a Major Regulatory Mechanism of Integrin-Mediated Adhesion
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Identification of Prognostic Glycolysis-Related lncRNA Signature in Tumor Immune Microenvironment of Hepatocellular CarcinomaPurpose: The purpose of this study was to construct a novel risk scoring model with prognostic value that could elucidate tumor immune microenvironment of hepatocellular carcinoma (HCC).Samples and methods: Data were obtained through The Cancer Genome Atlas (TCGA) database. Univariate Cox analysis, least absolute shrinkage and ...
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