Frontiers in Molecular Biosciences
SCOPUS (2014-2025)SCIE-ISI
2296-889X
Thụy Sĩ
Cơ quản chủ quản: Frontiers Media S.A.
Lĩnh vực:
Biochemistry, Genetics and Molecular Biology (miscellaneous)BiochemistryMolecular Biology
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Solvent Accessibility of Residues Undergoing Pathogenic Variations in Humans: From Protein Structures to Protein Sequences
Tập 7
Solvent accessibility (SASA) is a key feature of proteins for determining their
folding and stability. SASA is computed from protein structures with different
algorithms, and from protein sequences with machine-learning based approaches
trained on solved structures. Here we ask the question as to which extent
solvent exposure of residues can be associated to the pathogenicity of the
variation. By ...
Molecular Mechanisms Behind Anti SARS-CoV-2 Action of Lactoferrin
Tập 8
Despite the huge effort to contain the infection, the novel SARS-CoV-2
coronavirus has rapidly become pandemic, mainly due to its extremely high
human-to-human transmission capability, and a surprisingly high viral charge of
symptom-less people. While the seek for a vaccine is still ongoing, promising
results have been obtained with antiviral compounds. In particular, lactoferrin
is regarded to ha...
Non-lysine ubiquitylation: Doing things differently
Tập 9
The post-translational modification of proteins with ubiquitin plays a central
role in nearly all aspects of eukaryotic biology. Historically, studies have
focused on the conjugation of ubiquitin to lysine residues in substrates, but it
is now clear that ubiquitylation can also occur on cysteine, serine, and
threonine residues, as well as on the N-terminal amino group of proteins.
Paradigm-shiftin...
Adhesions Assemble!—Autoinhibition as a Major Regulatory Mechanism of Integrin-Mediated Adhesion
Tập 6
Identification of Prognostic Glycolysis-Related lncRNA Signature in Tumor Immune Microenvironment of Hepatocellular Carcinoma
Tập 8
Purpose: The purpose of this study was to construct a novel risk scoring model
with prognostic value that could elucidate tumor immune microenvironment of
hepatocellular carcinoma (HCC).Samples and methods: Data were obtained through
The Cancer Genome Atlas (TCGA) database. Univariate Cox analysis, least absolute
shrinkage and selection operator (LASSO) analysis, and multivariate Cox analysis
were...