Candidate Genes for Age at Menarche Are Associated With Uterine LeiomyomaFrontiers in Genetics - Tập 11
Irina Ponomarenko, Evgeny Reshetnikov, Alexey Polonikov, I.N. Verzilina, Inna Sorokina, Anna Yermachenko, Volodymyr Dvornyk, Mikhail Churnosov
Age at menarche (AAM) is an important marker of the pubertal development and
function of the hypothalamic–pituitary–ovarian system. It was reported as a
possible factor for a risk of uterine leiomyoma (UL). However, while more than
350 loci for AAM have been determined by genome-wide association studies (GWASs)
to date, no studies of these loci for their association with UL have been
conducted so ... hiện toàn bộ
An Effective Hypoxia-Related Long Non-Coding RNA Assessment Model for Prognosis of Lung AdenocarcinomaFrontiers in Genetics - Tập 13
Yuanshuai Li, Xiaofang Sun
Background: Lung adenocarcinoma (LUAD) represents one of the highest incidence
rates worldwide. Hypoxia is a significant biomarker associated with poor
prognosis of LUAD. However, there are no definitive markers of hypoxia-related
long non-coding RNAs (lncRNAs) in LUAD.Methods: From The Cancer Genome Atlas
(TCGA) and the Molecular Signatures Database (MSigDB), we acquired the
expression of hypoxia... hiện toàn bộ