Multi-Omic Analysis of the Microbiome and Metabolome in Healthy Subjects Reveals Microbiome-Dependent Relationships Between Diet and Metabolites

Zheng-Zheng Tang1,2, Guanhua Chen1, Qilin Hong3, Shi Huang4, Holly Smith5, Rachana Shah6, Matthew Scholz7, Jane F. Ferguson5,8
1Department of Biostatistics and Medical Informatics, University of Wisconsin–Madison, Madison, WI, United States
2Wisconsin Institute for Discovery, Madison, WI, United States
3Department of Statistics, University of Wisconsin–Madison, Madison, WI, United States
4Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States
5Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, United States
6Division of Pediatric Endocrinology, Children’s Hospital of Philadelphia, Philadelphia, PA, United States
7Vanderbilt Technologies for Advanced Genomics (VANTAGE), Vanderbilt University Medical Center, Nashville, TN, United States
8Vanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC), Vanderbilt University Medical Center, Nashville, TN, United States

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