Frontiers in Biology

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MicroRNAs in erythropoiesis and red blood cell disorders
Frontiers in Biology - Tập 10 - Trang 321-332 - 2015
Javad Mohammdai-asl, Abolfazl Ramezani, Fatemeh Norozi, Amal Saki Malehi, Ali Amin Asnafi, Mohammad Ali Jalali Far, Seyed Hadi Mousavi, Najmaldin Saki
MicroRNAs (miRNAs) are 19-24 nucleotide non-coding ribonucleic acids binding DNA or RNA and controlling gene expression via mRNA degradation or its transcription inhibition. Erythropoies is a multi step differentiation process of erythroid progenitors to nucleate red blood cells. Maturation, proliferation and differentiation of red blood cells is affected by erythroid factors, signaling pathways i...... hiện toàn bộ
An overview of pyrethroid insecticides
Frontiers in Biology - Tập 13 - Trang 79-90 - 2018
Anudurga Gajendiran, Jayanthi Abraham
Pesticides are used to control various pests of agricultural crops worldwide. Despite their agricultural benefits, pesticides are often considered a serious threat to the environment because of their persistence. Pyrethroids are synthetic derivates of pyrethrins, which are natural organic insecticides procured from the flowers of Chrysanthemum cinerariaefolium and C. coccineum. Pyrethroids are cla...... hiện toàn bộ
Comparative analysis of chromosome segregation in human, yeasts and trypanosome
Frontiers in Biology - - 2014
Xianxian Han, Ziyin Li
Salicylic acid-mediated plant defense: Recent developments, missing links, and future outlook
Frontiers in Biology - - 2017
Ian Arthur Palmer, Zhenhua Shang, Zheng Qing Fu
Plant pathogens are responsible for many of history’s greatest famines. Understanding how plants defend themselves against pathogens is crucial to preventing future famines. Salicylic acid (SA)-mediated plant defense is a key defense pathway, which plants use to defend against biotrophic and hemi-biotrophic pathogens. As a master regulator of SAmediated plant defense, NPR1 interacts with TGA and W...... hiện toàn bộ
Relationship between breast arterial calcification on mammography with coronary CT angiography findings
Frontiers in Biology - Tập 13 - Trang 309-313 - 2018
Mohammad Ghasem Hanafi, Mojgan Samet Zadeh, Mohammad Momeni, Sorour Rajabkordi
Breast arterial calcification is a frequently benign finding on mammography that usually is not reported. An increasing attention has been formed to determine the association between breast arterial calcification (BAC) and Coronary artery disease. In the current study we have aimed to evaluate the relationship between BAC on mammography with coronary CT angiography findings. The case control study...... hiện toàn bộ
Cellular functions of MLL/SET-family histone H3 lysine 4 methyltransferase components
Frontiers in Biology - Tập 11 - Trang 10-18 - 2016
J. K. Bailey, Dzwokai Ma
The MLL/SET family of histone H3 lysine 4 methyltransferases form enzyme complexes with core subunits ASH2L, WDR5, RbBP5, and DPY-30 (often abbreviated WRAD), and are responsible for global histone H3 lysine 4 methylation, a hallmark of actively transcribed chromatin in mammalian cells. Accordingly, the function of these proteins is required for a wide variety of processes including stem cell diff...... hiện toàn bộ
Epigenetic regulators sculpt the plastic brain
Frontiers in Biology - Tập 12 - Trang 317-332 - 2017
Ji-Song Guan, Hong Xie, San-Xiong Liu
Epigenetic regulation is a level of transcriptional regulation that occurs in addition to the genetic programming found in biological systems. In the brain, the epigenetic machinery gives the system an opportunity to adapt to a given environment to help not only the individual but also the species survive and expand. However, such a regulatory system has risks, as mutations resulting from epigenet...... hiện toàn bộ
Functional role of metalloproteins in genome stability
Frontiers in Biology - Tập 11 - Trang 119-131 - 2016
Chunqiang Zhang, Fan Zhang, Ping Zhou, Caiguo Zhang
Cells contain a large number of metalloproteins that commonly harbor at least one metal ion cofactor. In metalloproteins, metal ions are usually coordinated by oxygen, sulfur, or nitrogen centers belonging to amino acid residues in the protein. The presence of the metal ion in metalloproteins allows them to take part in diverse biological processes, such as genome stability, metabolic catalysis, a...... hiện toàn bộ
Identification of cancer stem cells: from leukemia to solid cancers
Frontiers in Biology - Tập 5 - Trang 407-416 - 2010
Yinghui Huang, Xiaoxue Qiu, Ji-Long Chen
Cancer stem cells (CSCs) are widely considered to be a small cell population in leukemia and many solid cancers with the properties including self-renewal and differentiation to non-tumorigenic cancer cells. Identification and isolation of CSCs significantly depend on the special surface markers of CSCs. Aberrant gene expression and signal transduction contribute to malignancies of CSCs, which res...... hiện toàn bộ
Drosophila embryo syncytial blastoderm cellular architecture and morphogen gradient dynamics: Is there a correlation?
Frontiers in Biology - Tập 7 - Trang 73-82 - 2012
Aparna Sherlekar, Richa Rikhy
During embryo development in many metazoan animals, the first differentiated cell type to form is an epithelial cell. This epithelial layer is modified by developmental cues of body axes formation to give rise to various tissues. The cells that arise are mesenchymal in nature and are a source of other tissue types. This epithelial to mesenchymal transition is used for tissue type formation and als...... hiện toàn bộ
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