Renal failure in multiple myeloma: reversibility and impact on the prognosis Tập 65 Số 3 - Trang 175-181 - 2000
Lene Meldgaard Knudsen, Martin Hjorth, Erik Hippe
Abstract: The purpose of the present study was to analyse the importance and prognostic value of renal failure in multiple myeloma patients. The frequency and reversibility of renal failure in 775 multiple myeloma patients diagnosed between 1984–86 and 1990–92 in the Nordic countries were studied. Renal failure, defined as plasma creatinine >130μmol/l, was observed in 29% of the cases a...... hiện toàn bộ Isolation and characterization of a tumor necrosis factor binding protein from urine Tập 42 Số 3 - Trang 270-275 - 1989
Inge Olsson, Mikael Lantz, Eva Nilsson, Christina Peetre, Hans Thysell, Anders Grubb, G.R. Adolf
Tumor necrosis factor (TNF)/cachectin can produce both beneficial and harmful manifestations. Mechanisms may operate to counteract potentially harmful effects such as shock and cachexia. The TNF binding protein (TNF‐BP), which is found at increased levels in serum and urine of patients with chronic renal failure, may play such a role. TNF‐BP was purified 1000000–fold to homogeneity from ur...... hiện toàn bộ Defensins Tập 44 Số 1 - Trang 1-8 - 1990
Tomas Ganz, Michael E. Selsted, Robert I. Lehrer
Abstract: Defensins are a family of small, variably cationic proteins which are highly abundant in the granules of mammalian phagocytes. Three defensins, HNP‐1, 2, and 3, comprise 30–50% of total protein in azurophil granules of human neutrophils. Some defensins are broadly antimicrobial, antiviral and cytotoxic, while others are chemotactic, opsonic, or may modulat...... hiện toàn bộ Differential expression of microRNAs in hematopoietic cell lineages Tập 81 Số 4 - Trang 304-310 - 2008
Michaela Dostálová Merkerová, Monika Beličková, Hana Votavová
AbstractObjectives: MicroRNAs (miRNAs) play key roles in a wide variety of normal and pathological cellular processes. A number of studies identified hematopoietic‐specific miRNAs that are necessary for correct function of blood cells. Out of our microarray data, we chose 13 miRNAs that showed differential expression in peripheral blood cell...... hiện toàn bộ Biology of the hemopoietic microenvironment Tập 49 Số 5 - Trang 225-233 - 1992
Héctor Mayani, Larry J. Guilbert, Anna Janowska‐Wieczorek
Abstract: In adult mammals, hemopoiesis takes place primarily in the bone marrow. The steady‐state production of blood cells depends to a large extent on the interaction between hemopoietic stem/progenitor cells (HPC) and the different components of the microenvironment present in the medullary cavity. During the last three decades, in vivo... hiện toàn bộ Circulating endothelial cells in vascular disorders: new insights into an old concept Tập 65 Số 4 - Trang 215-220 - 2000
Françoise Dignat‐George
Abstract: The endothelial contribution to vascular disorders has been widely documented in experimental models. However, its implication in human pathology is difficult to investigate, owing to the paucity of non‐invasive methods and of specific endothelial markers. The enumeration of circulating endothelial cells (CEC) released in peripheral blood after vascular injury represents a direct...... hiện toàn bộ Tình trạng tim mạch ở bệnh nhân thalassemia nặng được điều trị tốt Dịch bởi AI Tập 73 Số 5 - Trang 359-366 - 2004
Athanasios Aessopos, Dimitrios Farmakis, Antonia Hatziliami, Christina Fragodimitri, Fotis Karabatsos, Jacqueline Joussef, Eftichia Mitilineou, Evanthia Diamanti‐Kandaraki, John Meletis, Markisia Karagiorga
Tóm tắt: Mục tiêu: Đánh giá tình trạng tim mạch ở một nhóm lớn bệnh nhân thalassemia nặng đã được điều trị theo cách tiêu chuẩn từ khi còn nhỏ với liệu pháp truyền máu tích cực và chelat deferoxamine, những người có tuân thủ tốt phác đồ điều trị này. Phương pháp và Kết quả: Chúng tôi đã tiến hành đánh giá lâm sàn...... hiện toàn bộ Veno‐occlusive disease of the liver after hemopoietic cell transplantation Tập 64 Số 5 - Trang 281-291 - 2000
Enric Carreras
Abstract: The clinical syndrome of veno‐occlusive disease (VOD) after hemopoietic cell transplantation is characterised by jaundice, painful liver enlargement, and fluid retention with weight gain. Cytoreductive therapy is presumably the primary cause of VOD, but several other agents (and a special susceptibility of the liver) can also play a role in its genesis. The risk of VOD can be pre...... hiện toàn bộ Prophylactic heparin does not prevent liver veno‐occlusive disease following autologous bone marrow transplantation Tập 47 Số 5 - Trang 346-354 - 1991
L. Marsa‐Vila, Norbert Claude Gorin, J.P. Laporte, Myriam Labopin, M. C. Dupuy‐Montbrun, L Fouillard, F Isnard, A Najman
Abstract: Veno‐occlusive disease (VOD) is a major cause of toxic death after autologous bone marrow transplantation (ABMT). We studied the potential role of continuous administration of low‐dose heparin for VOD prevention in 234 consecutive patients who underwent ABMT in our institution. The population consisted of 98 patients autografted before October 1984 who did...... hiện toàn bộ