Diagnostic Pathology

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Ovarian cancer: diagnostic accuracy and tumor types distribution in East Africa compared to North America
Diagnostic Pathology - Tập 15 - Trang 1-11 - 2020
Peter F. Rambau, Martin Köbel, Derek Tilley, Alex Mremi, Robert Lukande, William Muller
Ovarian cancer is a spectrum of several histologically distinct tumor types that differ in etiology, response to therapy, and prognosis. In resource-limited settings, the diagnosis of ovarian cancer can be challenging. This study describes the distribution of ovarian cancer tumor types in East Africa as well as assessing the diagnostic accuracy by using contemporary methods. Data from 210 women id...... hiện toàn bộ
Diagnostic value of clusterin immunostaining in hepatocellular carcinoma
Diagnostic Pathology - Tập 15 - Trang 1-7 - 2020
Yuan Li, Fangfang Liu, Wendi Zhou, Sharon Zhang, Peiguo Chu, Fan Lin, Hanlin L. Wang
Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge. Existing biomarkers are of limited diagnostic value. Our previous studies observed an enhanced canalicular expression pattern of clusterin (CLU) in HCC, which was not observed in benign hepatocellular mass lesions such as hepatocellular adenoma. The aim of ...... hiện toàn bộ
Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern Switzerland
Diagnostic Pathology - Tập 14 - Trang 1-14 - 2019
Alexandra Grosse, Claudia Grosse, Markus Rechsteiner, Alex Soltermann
Molecular testing of lung adenocarcinoma for oncogenic driver mutations has become standard in pathology practice. The aim of the study was to analyze the EGFR, KRAS, ALK, RET, ROS1, BRAF, ERBB2, MET and PIK3CA mutational status in a representative cohort of Swiss patients with lung adenocarcinoma and to correlate the mutational status with clinicopathological patient characteristics. All patients...... hiện toàn bộ
Histopathological grading of breast ductal carcinoma In Situ: validation of a web-based survey through intra-observer reproducibility analysis
Diagnostic Pathology - Tập 10 - Trang 1-10 - 2015
Fernando Schuh, Jorge Villanova Biazús, Erika Resetkova, Camila Zanella Benfica, Alessandra de Freitas Ventura, Diego Uchoa, Márcia Graudenz, Maria Isabel Albano Edelweiss
Histopathological grading diagnosis of ductal carcinoma in situ (DCIS) of the breast may be very difficult even for experts, and it is important for therapeutic decisions. The challenge may be due to the inaccurate and/or subjective application of the diagnosis criteria. The aim of this study was to investigate the intra-observer agreement between a traditional method and a developed web-based que...... hiện toàn bộ
Recurrent adult jejuno-jejunal intussusception due to inflammatory fibroid polyp – Vanek’s tumour: a case report
Diagnostic Pathology - Tập 9 Số 1 - 2014
Kieran Joyce, Peadar S Waters, Ronan Waldron, Iqbal Khan, Zolt S Orosz, Tamás Németh, Kevin Barry
Yolk sac tumor differentiation in urothelial carcinoma of the urinary bladder: a case report and differential diagnosis
Diagnostic Pathology - Tập 15 - Trang 1-7 - 2020
Nadia Espejo-Herrera, Enric Condom-Mundó
Yolk sac tumor (YST) is a germ cell neoplasm that arises predominantly in the gonads, but can also derive from somatic neoplasms in extragonadal locations. These latter cases have been documented in several organs, although reports from the urinary tract are limited. To our knowledge, this is the first report of a bladder urothelial carcinoma with a predominant component of YST differentiation. We...... hiện toàn bộ
Retraction Note: The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1
Diagnostic Pathology - Tập 13 - Trang 1-1 - 2018
Huifen Li, Weihua Huang, Rongcheng Luo
The editor has retracted this article [1] because it shows significant overlap with the following articles (amongst others) [2, 3]. None of the authors responded to correspondence regarding this retraction.
Multicystic urothelial carcinoma of the bladder with gland-like lumina and with signet-ring cells. A case report
Diagnostic Pathology - Tập 3 - Trang 1-4 - 2008
Isabel Alvarado-Cabrero, Delia Pérez-Montiel, Ondrej Hes
We present the case of 80-year-old male with superficial papillary urothelial carcinoma of the urinary bladder with striking multicystic architecture with a combination of features of urothelial carcinoma with gland-like lumina, with signet-ring cell differentiation and microcystic pattern. However, the tumor shared the morphologic features of several variants of urothelial carcinoma, the most imp...... hiện toàn bộ
Association of promoter methylation with histologic type and pleural indentation in non-small cell lung cancer (NSCLC)
Diagnostic Pathology - Tập 6 - Trang 1-9 - 2011
Meiju Ji, Yong Zhang, Bingyin Shi, Peng Hou
Lung cancer is a major cause of death worldwide. Gene promoter methylation is a major inactivation mechanism of tumor-related genes, some of which can be served as a biomarker for early diagnosis and prognosis evaluation of lung cancer. We determined the promoter methylation of 6 genes using quantitative methylation-specific PCR (Q-MSP) technique in 96 clinically well-characterized non-small cell ...... hiện toàn bộ
Composite lymphoma in the anterior mediastinum: a case report and review of the literature
Diagnostic Pathology - Tập 6 - Trang 1-7 - 2011
Guohua Yu, Lingling Kong, Guimei Qu, Qian Zhang, Wei Wang, Lei Jiang
We recently encountered an unusual case of Composite lymphoma (CL) in the anterior mediastinum arising in a 37-year-old woman who presented initially with continuous pain in the right shoulder and chest. The woman had been suffered from continuous pain for three months before she went to our department of cardiovascular surgery. Chest computed tomography scan revealed the oval space-occupying lesi...... hiện toàn bộ
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