DARU Journal of Pharmaceutical Sciences
SCIE-ISI SCOPUS (2000-2025)
2008-2231
Cơ quản chủ quản: BioMed Central Ltd. , SPRINGER INT PUBL AG
Lĩnh vực:
PharmacologyMedicine (miscellaneous)Drug Discovery
Phân tích ảnh hưởng
Các bài báo tiêu biểu
A systematic review on status of lead pollution and toxicity in Iran; Guidance for preventive measures
Tập 20 Số 1 - 2012
Abstract Lead is an old environmental metal which is presented everywhere and
lead poisoning is an important health issue in many countries in the world
including Iran. It is known as a silent environmental disease which can have
life-long adverse health effects. In children, the most vulnerable population,
mental development of children health effects is of the greatest influence. Low
level lead ...
Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
Tập 22 Số 1 - 2014
Abstract Background Antidepressants have been shown to affect levels of
brain-derived neurotrophic factor (BDNF) and VGF (non-acronymic) whose
transcriptions are dependent on cAMP response element binding protein (CREB) in
long term treatment. The aim of this study was to verify the subacute
antidepressant effects of crocin, an active constituent of saffron (Crocus
sativus L.), and its effects on ...
Surface modification of PLGA nanoparticles via human serum albumin conjugation for controlled delivery of docetaxel
Tập 21 Số 1 - 2013
Abstract Background Poly lactic-co-glycolic acid (PLGA) based nanoparticles are
considered to be a promising drug carrier in tumor targeting but suffer from the
high level of opsonization by reticuloendothelial system due to their
hydrophobic structure. As a result surface modification of these nanoparticles
has been widely studied as an essential step in their development. Among various
surface m...
Selenium nanoparticle-enriched Lactobacillus brevis causes more efficient immune responses in vivo and reduces the liver metastasis in metastatic form of mouse breast cancer
- 2013
Abstract Background and the purpose of the study Selenium enriched Lactobacillus
has been reported as an immunostimulatory agent which can be used to increase
the life span of cancer bearing animals. Lactic acid bacteria can reduce
selenium ions to elemental selenium nanoparticles (SeNPs) and deposit them in
intracellular spaces. In this strategy two known immunostimulators, lactic acid
bacteria (...
Physico-chemical characterization and pharmacological evaluation of sulfated polysaccharides from three species of Mediterranean brown algae of the genus Cystoseira
Tập 23 Số 1 - 2015
Abstract Background Seaweed polysaccharides are highly active natural substances
having valuable applications. The present study was conducted to characterize
the physico-chemical properties of sulphated polysaccharides from three
Mediterranean brown seaweeds (Cystoseira sedoides, Cystoseira compressa and
Cystoseira crinita) and to evaluate their anti-radical, anti-inflammatory and
gastroprotectiv...
Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis
- 2015
Abstract Background Cordyceps militaris has been used as a traditional medicine
in Asian countries for a long time. Different types of Cordyceps extract were
reported to have various pharmacological activities including an anti-cancer
effect. We investigated the inhibitory effect of Cordyceps militaris ethanol
extract on a human colorectal cancer-derived cell line, RKO. Methods RKO cells
were trea...
The hypoglycemic effect of Juglans regia leaves aqueous extract in diabetic patients: A first human trial
- 2014
Abstract Background Juglans regia L. (J. regia ) is one of the medicinal plants
traditionally used for treatment of diabetes in Iranian medicine. The effect of
this plant has already been investigated on animal models; however, this is the
first study conducted on human subjects. The aim of this study is to investigate
the hypoglycemic effect of J. regia leaves aqueous extract in type 2 diabetes
p...
Formation of nanosuspensions in bottom-up approach: theories and optimization
Tập 27 Số 1 - Trang 451-473 - 2019
Review of recently used techniques and materials to improve the efficiency of orally administered proteins/peptides
- 2020
Abstract Objectives The main objective of present review is to explore and
evaluate the effectiveness of recently developed methods to improve the
bioavailability of orally administered biopharmaceutical drugs. Methods A
systematic search of sciencedirect, tandfonline and Google Scholar databases
based on various sets of keywords was performed. All results were evaluated
based on their abstracts, ...
Increasing the risk of spontaneous abortion and major malformations in newborns following use of serotonin reuptake inhibitors during pregnancy: A systematic review and updated meta-analysis
- 2012
Abstract Selective serotonin reuptake inhibitors (SSRIs) are the most frequently
used antidepressants during pregnancy. There are conflicting results about their
influence on pregnancy outcomes. The goal of this study was to update our
previous meta-analysis about pregnancy outcomes following exposure to SSRIs. For
this purpose, all relevant databases were searched from 1990 to March 2012 for
stud...