DARU Journal of Pharmaceutical Sciences
SCIE-ISI SCOPUS (2000-2023)
2008-2231
Cơ quản chủ quản: BioMed Central Ltd. , SPRINGER INT PUBL AG
Lĩnh vực:
PharmacologyMedicine (miscellaneous)Drug Discovery
Các bài báo tiêu biểu
A systematic review on status of lead pollution and toxicity in Iran; Guidance for preventive measuresAbstract
Lead is an old environmental metal which is presented everywhere and lead poisoning is an important health issue in many countries in the world including Iran. It is known as a silent environmental disease which can have life-long adverse health effects. In children, the most vulnerable population, mental development of children health effects is... ...
Tập 20 Số 1 - 2012
Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampusAbstract
Background
Antidepressants have been shown to affect levels of brain-derived neurotrophic factor (BDNF) and VGF (non-acronymic) whose transcriptions are dependent on cAMP response element binding protein (CREB) in long term treatment. The aim of this study was to verify the subacute anti... ...
Tập 22 Số 1 - 2014
Advances in toxicology and medical treatment of chemical warfare nerve agentsAbstract
Organophosphorous (OP) Nerve agents (NAs) are known as the deadliest chemical warfare agents. They are divided into two classes of G and V agents. Most of them are liquid at room temperature. NAs chemical structures and mechanisms of actions are similar to OP pesticides, but their toxicities are higher than these compounds. The main mechanism of ... ...
Tập 20 Số 1 - 2012
Surface modification of PLGA nanoparticles via human serum albumin conjugation for controlled delivery of docetaxelAbstract
Background
Poly lactic-co-glycolic acid (PLGA) based nanoparticles are considered to be a promising drug carrier in tumor targeting but suffer from the high level of opsonization by reticuloendothelial system due to their hydrophobic structure. As a result surface modification of these n... ...
Tập 21 Số 1 - 2013
Selenium nanoparticle-enriched Lactobacillus brevis causes more efficient immune responses in vivo and reduces the liver metastasis in metastatic form of mouse breast cancerAbstract
Background and the purpose of the study
Selenium enriched Lactobacillus has been reported as an immunostimulatory agent which can be used to increase the life span of cancer bearing animals. Lactic acid bacteria can reduce selenium ions to elemental selenium na... ...
- 2013
Preparation, characterization and optimization of sildenafil citrate loaded PLGA nanoparticles by statistical factorial design
Tập 21 - Trang 1-10 - 2013
The objective of the present study was to formulate and optimize nanoparticles (NPs) of sildenafil-loaded poly (lactic-co-glycolic acid) (PLGA) by double emulsion solvent evaporation (DESE) method. The relationship between design factors and experimental data was evaluated using response surface methodology. A Box-Behnken design was made considering the mass ratio of drug to polymer (D/P), the vol......
Physico-chemical characterization and pharmacological evaluation of sulfated polysaccharides from three species of Mediterranean brown algae of the genus CystoseiraAbstract
Background
Seaweed polysaccharides are highly active natural substances having valuable applications. The present study was conducted to characterize the physico-chemical properties of sulphated polysaccharides from three Mediterranean brown seaweeds (Cystoseira sedoides...
Tập 23 Số 1 - 2015
Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosisAbstract
Background
Cordyceps militaris has been used as a traditional medicine in Asian countries for a long time. Different types of Cordyceps extract were reported to have various pharmacological activities including an anti-cancer effect. We investiga... ...
- 2015
The hypoglycemic effect of Juglans regia leaves aqueous extract in diabetic patients: A first human trialAbstract
Background
Juglans regia L. (J. regia ) is one of the medicinal plants traditionally used for treatment of diabetes in Iranian medicine. The effect of this plant has already been investigated on animal models; however, ... ...
- 2014
Formation of nanosuspensions in bottom-up approach: theories and optimization
Tập 27 Số 1 - Trang 451-473 - 2019