Advances in toxicology and medical treatment of chemical warfare nerve agents Tập 20 Số 1 - 2012
Mohammd Moshiri, Emadodin Darchini-Maragheh, Mahdi Balali-Mood
Abstract
Organophosphorous (OP) Nerve agents (NAs) are known as the deadliest chemical warfare agents. They are divided into two classes of G and V agents. Most of them are liquid at room temperature. NAs chemical structures and mechanisms of actions are similar to OP pesticides, but their toxicities are higher than these compounds. The main mechanism of ...... hiện toàn bộ Preparation, characterization and optimization of sildenafil citrate loaded PLGA nanoparticles by statistical factorial design Tập 21 - Trang 1-10 - 2013
Elham Ghasemian, Alireza Vatanara, Abdolhossein Rouholamini Najafabadi, Mohammad Reza Rouini, Kambiz Gilani, Majid Darabi
The objective of the present study was to formulate and optimize nanoparticles (NPs) of sildenafil-loaded poly (lactic-co-glycolic acid) (PLGA) by double emulsion solvent evaporation (DESE) method. The relationship between design factors and experimental data was evaluated using response surface methodology. A Box-Behnken design was made considering the mass ratio of drug to polymer (D/P), the vol...... hiện toàn bộ