Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis
Tóm tắt
RKO cells were treated with various concentrations of nucleosides-enriched ethanol extract of
RKO cells were highly susceptible to the ethanol extract of
Ethanol extract of
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Kunjadia PD, Nagee A, Pandya PY, Mukhopadhyaya PN, Sanghvi GV, Dave GS. Medicinal and antimicrobial role of the oyster culinary-medicinal mushroom Pleurotus ostreatus (higher Basidiomycetes) cultivated on banana agrowastes in India. Int J Med Mushrooms. 2014;16:227–38.
Phan CW, Lee GS, Macreadie IG, Malek SN, Pamela D. Lipid constituents of the edible mushroom, Pleurotus giganteus demonstrate anti-Candida activity. Nat Prod Commun. 2013;8:1763–5.
Kim SP, Nam SH, Friedman MJ. Hericium erinaceus (Lion’s Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice. Agric Food Chem. 2013;61:4898–904.
Yang Y, Hu J, Liu Y, Feng N, Chen H, Tang Q, et al. Antioxidant and cytotoxic activities of ethanolic extracts and isolated fractions of species of the genus Phellinus Quél. (Aphyllophoromycetideae). Int J Med Mushrooms. 2011;13:145–52.
Lin JG, Fan MJ, Tang NY, Yang JS, Hsia TC, Lin JJ, et al. An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo. Integr Cancer Ther. 2012;11:29–36.
Tuli HS, Sharma AK, Sandhu SS, Kashyap D. Cordycepin: a bioactive metabolite with therapeutic potential. Life Sci. 2013;93:863–9.
Yue K, Ye M, Zhou Z, Sun W, Lin X. The genus Cordyceps: a chemical and pharmacological review. J Pharm Pharmacol. 2013;65:474–93.
Zhou X, Gong Z, Su Y, Lin J, Tang K. Cordyceps fungi: natural products, pharmacological functions and developmental products. J Pharm Pharmacol. 2009;61:279–91.
Park C, Hong SH, Lee JY. Growth inhibition of U937 leukemia cells by aqueous extract of Cordyceps militaris through induction of apoptosis. Oncol Rep. 2005;13:1211–6.
Lee H, Kim YJ, Kim HW, Lee DH, Sung MK, Park T. Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemiaHL-60 cells. Biol Pharm Bull. 2006;29:670–4.
Lee HH, Park H, Sung GH, Lee K, Lee T, Cho H. Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA/2 mouse model. J Microbiol. 2014;52:696–701.
Zhai XF, Chen ZB, Shen LF, Fan J, Zhou WP, Yang YK, et al. Traditional herbal medicine in preventing recurrence after resection of small hepatocellular carcinoma: a multicenter randomized controlled trial. J Integr Med. 2013;11:90–100.
Ling CQ, Yue XQ, Ling C. Three advantages of using traditional Chinese medicine to prevent and treat tumor. J Integr Med. 2014;12:331–5.
Li ZP, Zeng JQ, Hu AM. Clinical study on the qi and xue dual-supply therapy with chemotherapy to prevent the recurrence and metastasis from colorectal carcinoma. Shi Yong Ai Zheng Za Zhi. 2010;25:618–20.
John A, Kaabi SA, Dweik N, Yakoub R, Abdulla F. Emerging role for colorectal cancer screening in Asian countries. Trop Gastroenterol. 2014;35:21–4.
Lim HW, Kwon YM, Cho SM, Kim JH, Yoon GH. Antitumor activity of Cordyceps militaris on human cancer cell line. Korean J Pharmacogn. 2009;35:364–7.
Park SE, Yoo HS, Jin CY, Hong SH, Lee YW, Kim BM. Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris. Food Chem Toxicol. 2009;47:1667–75.
Wu X, Deng Y. Bax and BH3-domain-only proteins in p53-mediated apoptosis. Front Biosci. 2002;7:151–6.
Murphy KM, Ranganathan V, Farnsworth M, Kavallaris LM, Lock RB. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 2000;7:102–11.
Cain K, Brown DG, Langlais C, Cohen GM. Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex. J Biol Chem. 1999;274:22686–92.
Adrain C, Slee EA, Harte MT, Martin SJ. Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region. J Biol Chem. 1999;274:20855–60.
Won SY, Park EH. Anti-inflammatory and related pharmacological activities of cultured mycelia and fruiting bodies of Cordyceps militaris. J Ethnopharmacol. 2005;96:555–61.
Son M, Lee M, Ryu E, Moon A, Jeong CS, Jung YW, et al. Genipin as a novel chemical activator of EBV lytic cycle. J Microbiol. 2015;53:155–65.
Boulares AH, Yakovlev AG, Ivanova V, Stoica BA, Wang G, Iyer S, et al. Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis; Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells. J Biol Chem. 1999;274:22932–40.
Yang CH, Kao YH, Huang KS, Wang CY, Lin W. Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells. Cell Death Dis. 2012;3, e431. doi:10.1038/cddis.
Park BT, Na KH, Jung EC, Par JW, Kim HH. Antifungal and anticancer activities of a protein from the mushroom cordyceps militaris. Korean J Physiol Pharmacol. 2009;1:49–54. doi:10.4196/kjpp.
Park SE, Kim JS, Lee YW, Yoo HS, Cho CK. Antitumor activity of water extracts from Cordyceps Militaris in NCI-H460 cell xenografted nude mice. J Acupunct Meridian Stud. 2009;2:294–300.
Mollah ML, Park DL, Park HJ. Cordyceps militaris grown on germinated soybean induces G2/M cell cycle arrest through down regulation of Cyclin B1 and Cdc25c in human colon cancer HT-29 Cells. Evid Based Complement Alternat Med. 2012;2012:249217.
Lee SY, Debnath T, Kim SK, Lim BO. Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29. Food Chem Toxicol. 2013;60:439–47.
Lee HH, Jeong JW, Lee JH, Kim GY, Cheong J, Jeong YK, et al. Cordycepin increases sensitivity of hep3b human hepatocellular carcinoma cells to trail-mediated apoptosis by inactivating the jnk signaling pathway. Oncol Rep. 2013;30:1257–64.
Sun YS, Lv LX, Zhao Z, He X, You L, Liu JK, et al. Cordycepol c induces caspase-independent apoptosis in human hepatocellular carcinoma hepg2 cells. Biol Pharm Bull. 2014;37:608–17.