DARU Journal of Pharmaceutical Sciences
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Preventive effect of Rumex crispus L. on surgically induced intra-abdominal adhesion model in rats
DARU Journal of Pharmaceutical Sciences - Tập 29 - Trang 101-115 - 2021
Rumex crispus L. (Polygonaceae), known as “Labada” in Turkey, was reported to be used for the treatment of gynecological diseases such as postpartum complications and infertility in folk medicine. Earlier studies on R. crispus have shown that leaf, fruit and root extracts have anti-inflammatory and antioxidant activities and are used for the treatment of tumors in the uterus. The hypothesis of thi......
Mentha longifolia syrup in secondary amenorrhea: a double-blind, placebo-controlled, randomized trials
DARU Journal of Pharmaceutical Sciences - Tập 20 - Trang 1-8 - 2012
Amenorrhea is defined as the cessation of menses. Hormone therapy is the most common treatment. Due to the contraindications and side effects of it and the increasing demand for alternative medicine substitutes, Mentha longifolia L. was used in this study. Mentha longifolia L. is a known medication in Iranian traditional medicine to induce menstrual bleeding in women with secondary amenorrhea and ......
Psychotropic medication in children and adolescents in the United States in the year 2004 vs 2014
DARU Journal of Pharmaceutical Sciences - Tập 26 - Trang 5-10 - 2018
There is a global perception that psychotropic utilization in children and adolescents is increasing in the US. We present prevalent estimates for all psychotropics prescribed in the US (using commercial claims from Medicare and Medicaid) to children and adolescents in 2004 (total population N = 6,808,453) and in 2014 (total population N = 11,082.260). Further we evaluated if there has been a stat......
In vitro anti-proliferative activities of the sterols and fatty acids isolated from the Persian Gulf sponge; Axinella sinoxea
DARU Journal of Pharmaceutical Sciences - Tập 27 - Trang 121-135 - 2019
Marine sponges are rich sources of anticancer metabolites. Axinella sinoxea is a less studied sponge, found in the Larak Island’s waters, of the Persian Gulf. In the present study, we have explored the cytotoxic properties and chemical constituents of A. sinoxea. Repeated silica gel flash column chromatography of methanol extract of the Axinella sinoxea sponge, yielded fatty acid and sterol fracti......
A review on the synthesis of bio-based surfactants using green chemistry principles
DARU Journal of Pharmaceutical Sciences - Tập 30 - Trang 407-426 - 2022
With increasing awareness of the potential adverse impact of conventional surfactants on the environment and human health, there is mounting interest in the development of bio-based surfactants (which are deemed to be safer, more affordable, are in abundance, are biodegradable, biocompatible and possess scalability, mildness and performance in formulation) in personal care products. A comprehensiv......
Using the transtheoretical model’s stages of change to predict medication adherence in patients with type 2 diabetes mellitus in a primary health care setting
DARU Journal of Pharmaceutical Sciences - Tập 27 - Trang 91-99 - 2019
Qatar is currently experiencing a worrying increase in the prevalence of diabetes mellitus (DM). One of the most common reasons for uncontrolled DM is non-adherence to medications. The socio-behavioral intervention has proven effective in some chronic illnesses. To assess the stages of change (SOC) and medication adherence scores of type 2 diabetes mellitus (T2DM) patients visiting primary healthc......
Isotretinoin-associated Sweet’s syndrome: a case report
DARU Journal of Pharmaceutical Sciences - Tập 22 - Trang 1-4 - 2014
Sweet’s syndrome (SS) is characterized by various clinical symptoms, physical features, and pathological findings. Although cases of SS are very rare, there has been an increase in the incidence of drug-induced SS. Till date, there have been only few reported cases of isotretinoin-induced SS. In this report, we describe the case of a 19-year-old girl who developed SS after systemic treatment with ......
Formulation of inhalable lipid-based salbutamol sulfate microparticles by spray drying technique
DARU Journal of Pharmaceutical Sciences - Tập 22 - Trang 1-9 - 2014
The aim of this work was to develop dry powder inhaler (DPI) formulations of salbutamol sulfate (SS) by the aid of solid lipid microparticles (SLmPs), composed of biocompatible phospholipids or cholesterol. The SLmPs were prepared by using two different solvent systems (ethanol and water-ethanol) and lipid carriers (dipalmitoylphosphatidylcholine (DPPC) and cholesterol) with/without L-leucine in t......
Enhancement of the transdermal delivery of zidovudine by pretreating the skin with two physical enhancers: microneedles and sonophoresis
DARU Journal of Pharmaceutical Sciences - Tập 29 - Trang 279-290 - 2021
Zidovudine (AZT) has been the most widely used drug for antiretroviral therapy. In order to improve the therapy with this drug, different alternatives have been proposed, such as the transdermal administration. The use of permeation enhancers is necessary to favor the passage of this drug through the skin, due to its physicochemical properties and to the natural permeation barrier imposed by the s......
Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-finding trial
DARU Journal of Pharmaceutical Sciences - - Trang 1-9 - 2023
Colloid and/or co-load may be more effective than crystalloid for preventing postspinal anesthesia hypotension. We tested five different prophylactic norepinephrine dosages combined with colloid co-load infusion in patients receiving cesarean section and spinal anesthesia. Patients were randomly allocated to receive different prophylactic norepinephrine dosages (0 [NE 0 group], 0.025 [NE 25 group]......
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