Consequences of polyspermy in manCytogenetic and Genome Research - Tập 42 Số 1-2 - Trang 1-7 - 1986
R.R. Angell, Allan Templeton, Ioannis E. Messinis
Polyspermy occurs with a frequency of about 12% under some hormonal regimens
currently being used for in vitro fertilization and embryo transfer. Oocytes
with three pronuclei usually show normal cleavage and are morphologically
indistinguishable from embryos produced by normal fertilization. Chromosome
studies and DNA measurements on dispermic embryos show that about one-half are
triploid, the oth... hiện toàn bộ
Chromosomal localization of the human oncogene <i>ERBA2</i>Cytogenetic and Genome Research - Tập 43 Số 3-4 - Trang 150-153 - 1986
John R. Gosden, Peter G. Middleton, Derek Rout, Carmine De Angelis
The human ERBA2 gene has been mapped to chromosome 17q21.3 by in situ
hybridization. A second hybridization site at 17q25 was greatly reduced by high
stringency washes, indicating the presence of an additional member of the
ERBA2 family at this location. Southern blot hybridization using
identical conditions did not reveal additional bands, and hybridizations done at
sufficiently low... hiện toàn bộ
Hybrid genome evolution by transpositionCytogenetic and Genome Research - Tập 110 Số 1-4 - Trang 49-55 - 2005
Antonio Fontdevila
Species hybridization is reviewed focusing on its role as a source of
evolutionary novelties. Contrary to the view that hybrids are lineages devoid of
evolutionary value, a number of case studies are given that show how hybrids are
responsible for reticulate evolution that may lead to the origin of new species.
Hybrid evolution is mediated by extensive genome repatterning followed by rapid
stabili... hiện toàn bộ
TET Family of Dioxygenases: Crucial Roles and Underlying MechanismsCytogenetic and Genome Research - Tập 146 Số 3 - Trang 171-180 - 2015
Duo Li, Bin Guo, Jing Wang, Lina Tan, Qianjin Lu
DNA methylation plays an important role in the epigenetic regulation of
mammalian gene expression. TET (ten-eleven translocation) proteins, newly
discovered demethylases, have sparked great interest since their discovery. TET
proteins catalyze 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine
and 5-carboxylcytosine in 3 consecutive Fe(II)- and 2-oxoglutarate
(2-OG)-dependent oxidation ... hiện toàn bộ
Confirmed assignment of a novel human tyrosine kinase gene (JAK1A) to 1p32.3→p31.3 by nonisotopic in situ hybridizationCytogenetic and Genome Research - Tập 69 Số 3-4 - Trang 232-234 - 1995
William S. Modi, William L. Farrar, O. M. Zack Howard
JAK1A is a recently isolated class 3 (nonreceptor) tyrosine kinase that has
catalytic domain sequence homology with other kinases and is known to be
ubiquitously expressed in all human tissues thus far examined. The gene for this
enzyme had previously been localized to chromosome 1 using somatic cell hybrids
and linkage analyses. In the present study, fluorescence in situ hybridization
was utilize... hiện toàn bộ
Organization and expression of rat <i>Tspy</i>Cytogenetic and Genome Research - Tập 83 Số 3-4 - Trang 270-274 - 1998
F. Dechend, Stephanie Schubert, Indrajit Nanda, Tanja Vogel, Michael Schmid, Jörg Schmidtke
We have isolated both a full-length rat Tspy cDNA from testicular mRNA by
rapid amplification of cDNA ends (RACE) and RT-PCR
and a full-length rat Tspy gene from genomic DNA by PCR. In contrast to
the mouse, where Tspy is present in a single copy and is apparently
functionless, and to man and cattle, where TSPY is organized in a moderately
repetitiv... hiện toàn bộ
An Air-Drying Method for Meiotic Preparations from Mammalian TestesCytogenetic and Genome Research - Tập 3 Số 5 - Trang 289-294 - 1964
E. P. Evans, G. Breckon, C. E. Ford
A suspension is made in isotonic (2.2%) sodium citrate solution from the
contents of the tubules from a whole testis or a testicular biopsy specimen. The
germinal cells are sedimented by centrifuging, leaving most of the sperm in the
supernatant fluid, which is discarded. The cells are resuspended in hypo-tonic
(1%) sodium citrate solution and left to stand at room temperature for 12
minutes, afte... hiện toàn bộ
Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISHCytogenetic and Genome Research - Tập 68 Số 1-2 - Trang 45-48 - 1995
Fumiko Saito, Shiro Sasaki, A.B. Chepelinsky, Kiyohide Fushimi, Fumiaki Marumo, Tatsuro Ikeuchi
The human AQP2 (collecting duct water channel, aquaporin 2) gene encodes a 271
amino acid protein and is a member of the MIP (major intrinsic protein of lens
fiber) gene family. Using two-color fluorescence in situ hybridization on
high-resolution R-banded chromosomes and human genomic DNA clones for AQP2 and
MIP as probes, we found that both genes mapped closely within the human
chromosome region... hiện toàn bộ