BMC Infectious Diseases
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Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial
BMC Infectious Diseases - Tập 17 - Trang 1-9 - 2017
Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cure and prevention of recrudescence. In a randomized controlled clinical trial, we evaluated the 42-day parasitological outcomes of severe malaria treatment with intravenous artesunate (AS) or......
Construction of the influenza A virus transmission tree in a college-based population: co-transmission and interactions between influenza A viruses
BMC Infectious Diseases - Tập 16 - Trang 1-8 - 2016
Co-infection of different influenza A viruses is known to occur but how viruses interact within co-infection remains unknown. An outbreak in a college campus during the 2009 pandemic involved two subtypes of influenza A: persons infected with pandemic A/H1N1; persons infected with seasonal A/H3N2 viruses; and persons infected with both at the same time (co-infection). This provides data to analyse......
Human rhinovirus infection in young African children with acute wheezing
BMC Infectious Diseases - Tập 11 - Trang 1-8 - 2011
Infections caused by human rhinoviruses (HRVs) are important triggers of wheezing in young children. Wheezy illness has increasingly been recognised as an important cause of morbidity in African children, but there is little information on the contribution of HRV to this. The aim of this study was to determine the role of HRV as a cause of acute wheezing in South African children. Two hundred and ......
TNFA -308G>A and IL10 -1082A>G polymorphisms seem to be predictive biomarkers of chronic HCV infection
BMC Infectious Diseases - Tập 21 - Trang 1-8 - 2021
Genetic changes may induce dysregulated cytokine production and affect the progression of the chronic disease caused by the hepacivirus C (HCV) because the balance of pro- and anti-inflammatory cytokines determines the outcome of infection. This study evaluated the TNFA -308G>A and IL10 -1082A>G polymorphisms in the susceptibility and progress of chronic hepatitis C. The study included 101 samples......
Delayed diagnosis of tuberculosis in patients with diabetes mellitus co-morbidity and its associated factors in Zhejiang Province, China
BMC Infectious Diseases - Tập 21 - Trang 1-10 - 2021
Tuberculosis (TB) remains a significant global public health problem. China has the second highest TB burden in the world. With a growing TB population with diabetes mellitus (DM), the TB control system faces mounting challenges. To date, evidence remains inconclusive regarding the association between TB-DM co-morbidity and delayed diagnosis of TB patients. This study aims to assess the diagnostic......
Acinetobacter spp. bloodstream infection in hematological patients: a 10-year single-center study
BMC Infectious Diseases - Tập 23 - Trang 1-12 - 2023
This study investigated the clinical and antimicrobial characteristics of Acinetobacter spp. bloodstream infection (BSI) in hematological patients. Risk factors for 30-day mortality and carbapenem-resistant Acinetobacter spp. (CRA) BSI acquisition were also identified. We reviewed forty hematological patients with Acinetobacter spp. BSI in a large Chinese blood disease hospital between 2013 and 20......
The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis
BMC Infectious Diseases - Tập 18 - Trang 1-12 - 2018
Schistosomiasis, caused by Schistosoma japonicum, remains one of the most important parasitic diseases, and detection of S. japonicum infections in humans plays a crucial role in control and treatment. However, comparisons between the parasitological and the immunological examinations in the fields of China are lacking. Therefore we performed a meta-analysis to compare the seroprevalence of Schist......
Molecular epidemiology and clinical features of hand, foot and mouth disease in northern Thailand in 2016: a prospective cohort study
BMC Infectious Diseases - - 2018
Clinical characteristics and outcome of primary brain abscess: a retrospective analysis
BMC Infectious Diseases - Tập 21 - Trang 1-8 - 2021
Patients with primary brain abscess often present with atypical symptoms, and the outcome varies. We investigated the demographic, laboratory, and neuroimaging features of patients with brain abscess at our hospital and identified factors associated with their outcomes. We retrospectively collected the data of patients diagnosed with primary brain abscess at our hospital between January 2011 and D......
Growing burden of sepsis-related mortality in northeastern Italy: a multiple causes of death analysis
BMC Infectious Diseases - Tập 16 - Trang 1-6 - 2016
Few population-based data are available on mortality due to sepsis. The aim of the study was to estimate sepsis-related mortality rates and to assess the associated comorbidities. From multiple causes of death data (MCOD) of the Veneto Region (northeastern Italy), all deaths with sepsis mentioned anywhere in the death certificate were retrieved for the period 2008–2013. Among these deaths the prev......
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