Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trialBMC Infectious Diseases - Tập 17 - Trang 1-9 - 2017
Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde, Carine Karera-Gonahasa, Agnes N. Kiragga, Harriet Mayanja-Kizza, Noah Kiwanuka, Sam Nsobya, Ambrose O. Talisuna, Concepta Merry
Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cure and prevention of recrudescence. In a randomized controlled clinical trial, we evaluated the 42-day parasitological outcomes of severe malaria treatment with intravenous artesunate (AS) or...... hiện toàn bộ
Prolonged oral vancomycin for secondary prophylaxis of relapsing Clostridium difficile infectionBMC Infectious Diseases - Tập 19 - Trang 1-4 - 2019
Kevin Zhang, Patricia Beckett, Salaheddin Abouanaser, Vida Stankus, Christine Lee, Marek Smieja
Clostridium difficile infection (CDI) is an important cause of diarrhea and continues to be a major burden within healthcare institutions and in the community. For a small subset of patients with frequently relapsing CDI who do not have access to fecal microbiota transplantation (FMT), or fail FMT, there are no clear treatment recommendations. We review our experience with prolonged oral vancomyci...... hiện toàn bộ
Treatment outcomes in palliative care: the TOPCare study. A mixed methods phase III randomised controlled trial to assess the effectiveness of a nurse-led palliative care intervention for HIV positive patients on antiretroviral therapyBMC Infectious Diseases - Tập 12 - Trang 1-10 - 2012
Keira Lowther, Victoria Simms, Lucy Selman, Lorraine Sherr, Liz Gwyther, Hellen Kariuki, Aabid Ahmed, Zipporah Ali, Rachel Jenkins, Irene J Higginson, Richard Harding
Patients with HIV/AIDS on Antiretroviral Therapy (ART) suffer from physical, psychological and spiritual problems. Despite international policy explicitly stating that a multidimensional approach such as palliative care should be delivered throughout the disease trajectory and alongside treatment, the effectiveness of this approach has not been tested in ART-experienced populations. This mixed met...... hiện toàn bộ
Daptomycin Therapy for Osteomyelitis: A Retrospective StudyBMC Infectious Diseases - Tập 12 - Trang 1-6 - 2012
Jason C Gallagher, Jennifer A Huntington, Darren Culshaw, Scott A McConnell, Minjung Yoon, Elie Berbari
Daptomycin is a rapidly bactericidal agent with broad coverage against Gram-positive organisms, including Staphylococcus aureus, the most frequent cause of osteomyelitis. The objective of this study was to describe the clinical outcome of patients with non-hardware associated osteomyelitis, and the safety profile of daptomycin in the treatment of these infections. All patients with osteomyelitis, ...... hiện toàn bộ
Molecular characterization of ocular dirofilariasis: a case report of Dirofilaria immitis in south-eastern IranBMC Infectious Diseases - Tập 20 - Trang 1-5 - 2020
Razieh Parsa, Ali Sedighi, Iraj Sharifi, Mehdi Bamorovat, Saeid Nasibi
Dirofilariasis is a zoonotic parasitic infection transmitted from animals to humans by culicid mosquitoes. Although the disease can be caused by Dirofilaria spp. including Dirofilaria immitis and Dirofilaria repens, human ocular dirofilariasis due to D. immitis is relatively rare in the world. This study was aimed to present a case of ocular dirofilariasis caused by D. immitis in southeastern Iran...... hiện toàn bộ
Epidemiology of bloodstream infections in patients with acute myeloid leukemia undergoing levofloxacin prophylaxisBMC Infectious Diseases - Tập 13 - Trang 1-5 - 2013
Francesco Giuseppe De Rosa, Ilaria Motta, Ernesta Audisio, Chiara Frairia, Alessandro Busca, Giovanni Di Perri, Filippo Marmont
Infections are a common cause of morbidity and mortality in patients with acute myeloid leukemia (AML). The evidence for efficacy of antibiotic prophylaxis in reducing the mortality rates and the incidence of bacterial infections was also reported by a systematic review published by Cochrane in 2012. The objective of our study was to report the incidence and the etiology of bloodstream infections ...... hiện toàn bộ