DKK-1 in prostate cancer diagnosis and follow upBMC Clinical Pathology - Tập 14 - Trang 1-6 - 2014
Patrizia D’Amelio, Ilaria Roato, Marco Oderda, Francesco Soria, Andrea Zitella, Riccardo Ferracini, Giulio Mengozzi, Paolo Gontero, Giovanni Carlo Isaia
Dickoppf-1 (DKK-1) is a negative regulator of bone formation with tumorigenic potential. The up-regulation of DKK-1 is an early event in prostate cancer (PCa) development, thus we investigated its role as a marker in the diagnosis and prognosis of PCa. We retrospectively enrolled 159 patients who underwent prostate biopsy, either for elevated PSA or suspect digital rectal examination, between 2003...... hiện toàn bộ
Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancerBMC Clinical Pathology - Tập 17 - Trang 1-10 - 2017
Ayşe Latif, Amy L. Chadwick, Sarah J. Kitson, Hannah J. Gregson, Vanitha N. Sivalingam, James Bolton, Rhona J. McVey, Stephen A. Roberts, Kay M. Marshall, Kaye J. Williams, Ian J. Stratford, Emma J. Crosbie
Endometrial cancer (EC) is a major health concern due to its rising incidence. Whilst early stage disease is generally cured by surgery, advanced EC has a poor prognosis with limited treatment options. Altered energy metabolism is a hallmark of malignancy. Cancer cells drive tumour growth through aerobic glycolysis and must export lactate to maintain intracellular pH. The aim of this study was to ...... hiện toàn bộ
Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional studyBMC Clinical Pathology - Tập 12 - Trang 1-7 - 2012
Shweta Ujaoney, Mukta B Motwani, Shirish Degwekar, Vijay Wadhwan, Prajakta Zade, Minal Chaudhary, Vinay Hazarey, Tushar P Thakre, Manju Mamtani
Early detection holds the key to an effective control of cancers in general and of oral cancers in particular. However, screening procedures for oral cancer are not straightforward due to procedural requirements as well as feasibility issues, especially in resource-limited countries. We conducted a cross-sectional study to compare the performance of chemiluminescence, toluidine blue and histopatho...... hiện toàn bộ
Mycetoma in a non-endemic area: a diagnostic challengeBMC Clinical Pathology - Tập 17 - Trang 1-6 - 2017
Boubacar Efared, Layla Tahiri, Marou Soumana Boubacar, Gabrielle Atsam-Ebang, Nawal Hammas, El Fatemi Hinde, Laila Chbani
Mycetoma is a chronic granulomatous infectious disease caused by filamentous bacteria or by fungi. The disease is endemic in certain tropical and subtropical areas of the world but can be found elsewhere posing sometimes a diagnostic challenge for clinicians. A 65-year- old man presented with a right foot swelling evolving for 25 years. During that time, several diagnosis and treatments have been ...... hiện toàn bộ
Colorectal cancer in patients seen at the teaching hospitals of Guadeloupe and Martinique: discrepancies, similarities in clinicopathological features, and p53 statusBMC Clinical Pathology - Tập 14 - Trang 1-8 - 2014
Monique Decastel, Marlene Ossondo, Anne-Marie Andrea, Benoît Tressieres, Jacqueline Veronique-baudin, Jacqueline Deloumeaux, Marc Lubeth, Juliette Smith-ravin
In Guadeloupe and Martinique, two French Overseas Departments, colorectal cancer (CRC) has become an essential public health issue. However, little is known about CRC characteristics and the p53 status in these populations, particularly in Guadeloupe, whereas certification of a cancer registry has been recently validated. This was a descriptive retrospective study of 201 patients who, between 1995...... hiện toàn bộ
Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumorsBMC Clinical Pathology - Tập 12 - Trang 1-10 - 2012
Florence Brellier, Enrico Martina, Martin Degen, Nathalie Heuzé-Vourc’h, Agnès Petit, Thomas Kryza, Yves Courty, Luigi Terracciano, Christian Ruiz, Ruth Chiquet-Ehrismann
Tenascins are large glycoproteins found in the extracellular matrix of many embryonic and adult tissues. Tenascin-C is a well-studied biomarker known for its high overexpression in the stroma of most solid cancers. Tenascin-W, the least studied member of the family, is highly expressed in the stroma of colon and breast tumors and in gliomas, but not in the corresponding normal tissues. Other solid...... hiện toàn bộ
Central nervous system tumors: a single center pathology review of 34,140 cases over 60 yearsBMC Clinical Pathology - Tập 13 Số 1 - 2013
Liang Chen, Xiang Zou, Yin Wang, Ying Mao, Lei Zhou
Abstract
Background
Tumor epidemiology is a significant part of CNS (central nervous system) tumor studies. Reassessment of original sections can update our knowledge of tumor spectrum. Here, we discuss the features of CNS tumor pathology in a single center.
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