BMC Clinical Pathology

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Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors
BMC Clinical Pathology - Tập 12 - Trang 1-10 - 2012
Florence Brellier, Enrico Martina, Martin Degen, Nathalie Heuzé-Vourc’h, Agnès Petit, Thomas Kryza, Yves Courty, Luigi Terracciano, Christian Ruiz, Ruth Chiquet-Ehrismann
Tenascins are large glycoproteins found in the extracellular matrix of many embryonic and adult tissues. Tenascin-C is a well-studied biomarker known for its high overexpression in the stroma of most solid cancers. Tenascin-W, the least studied member of the family, is highly expressed in the stroma of colon and breast tumors and in gliomas, but not in the corresponding normal tissues. Other solid...... hiện toàn bộ
Comparison of the sensitivity of a 24 h-shell vial assay, and conventional tube culture, in the isolation of Herpes simplex virus – 1 from corneal scrapings
BMC Clinical Pathology - Tập 2 - Trang 1-5 - 2002
Sreedharan Athmanathan, Sesha Reddy Bandlapally, Gullapalli N Rao
Herpes simplex keratitis is a sight threatening ocular infection. A rapid and specific diagnosis is essential for the institution of specific antiviral therapy and to avoid complications that can arise from misdiagnosis and inappropriate treatment. Though a variety of techniques are available, isolation of Herpes simplex virus 1 (HSV-1) in culture provides the most reliable and specific method, an...... hiện toàn bộ
Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer
BMC Clinical Pathology - Tập 12 - Trang 1-12 - 2012
Marco Palma, Lissett Lopez, Margarita García, Nuria de Roja, Tamara Ruiz, Julita García, Elisabet Rosell, Carmen Vela, Paloma Rueda, María-Jose Rodriguez
Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of colorectal cancer (CRC) since they have shown an increase messenger RNA transcripts (mRNA) expression level in adenomas and colorectal tumours when compared to normal tissues. To evaluate CTHRC1 and NFE2L3 as cancer biomarkers, it was g...... hiện toàn bộ
A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer
BMC Clinical Pathology - Tập 13 - Trang 1-11 - 2013
Takayuki Kobayashi, Keiichi Iwaya, Tomoyuki Moriya, Tamio Yamasaki, Hitoshi Tsuda, Junji Yamamoto, Osamu Matsubara
Ki67 is widely used in order to distinguish the “A” and “B” subtypes of luminal-type breast cancer. This study aimed to validate the prognostic value of adding p53 to Ki67 for characterizing luminal-type breast cancer. Immunostaining for Ki67, p53, and the molecular markers HER2, CK5/6, CK14, EGFR, FOXA1, GATA3, and P-cadherin was examined hormone receptor (HR)-positive cancer tissues from 150 pat...... hiện toàn bộ
Performance of the Genotype® MTBDRPlus resistance patternSamara, Russian Federation
BMC Clinical Pathology - Tập 9 - Trang 1-9 - 2009
Vladyslav Nikolayevskyy, Yanina Balabanova, Tatyana Simak, Nadezhda Malomanova, Ivan Fedorin, Francis Drobniewski
Russia is a high tuberculosis (TB) burden country with a high prevalence of multidrug resistant tuberculosis (MDRTB). Molecular assays for detection of MDRTB on clinical specimens are not widely available in Russia. We performed an evaluation of the GenoType® MTBDRplus assay (HAIN Lifescience GmbH, Germany) on a total of 168 sputum specimens from individual patients at a public health laboratory i...... hiện toàn bộ
Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas
BMC Clinical Pathology - - 2012
Sveinung Wergeland Sørbye, Thomas K. Kilvaer, Andrey Yurjevich Valkov, Tom Dønnem, Eivind Smeland, Khalid Al-Shibli, Roy M. Bremnes, Lill-Tove Busund
Use of cultivation-dependent and -independent techniques to assess contamination of central venous catheters: a pilot study
BMC Clinical Pathology - - 2008
Mette Kathrine Larsen, Trine Rolighed Thomsen, Claus Moser, Niels Høiby, Per Halkjær Nielsen
Abstract Background Catheters are the most common cause of nosocomial infections and are associated with increased risk of mortality, length of hospital stay and cost. Prevention of infections and fast and correct diagnosis is highly important. ...... hiện toàn bộ
Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer
BMC Clinical Pathology - Tập 14 Số 1 - 2014
Elinor Bexe Lindskog, Kristoffer Derwinger, Bengt Gustavsson, Peter Falk, Yvonne Wettergren
A case report of iatrogenic deterioration of yet undiagnosed Rhombencephalitis; always be careful with corticoids
BMC Clinical Pathology - - 2018
Loes Mandigers, Jelle L. Epker
BMC Clinical Pathology Reviewer Acknowledgment 2015
BMC Clinical Pathology - Tập 16 - Trang 1-2 - 2016
Elaine Zhang
The editors of BMC Clinical Pathology would like to thank all our reviewers who have contributed to the journal in Volume 15 (2015).
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