Standardisierte mikroRNA-Analytik — die große Chance für Biomarkerstudien?BIOspektrum - - 2020
Maria Fauth, Meike J. Saul
AbstractCirculating microRNAs (miRs) represent promising diagnostic and prognostic biomarkers for various diseases. Despite the high number of biomarker studies, the results of these studies are hardly reproducible. This makes it difficult to transfer the results into clinical application. In this context, acceptance criteria for the quantification of miRs by rever...... hiện toàn bộ
Abseits der Regel — Terpene mit ungewöhnlichen KohlenstoffgerüstenBIOspektrum - Tập 28 - Trang 335-337 - 2022
Markus Buchhaupt
The natural substance class of terpenoids covers an extremely wide range of different structures, although their building block repertoire is strongly limited. Methyltransferases from bacterial natural product pathways can add carbon atoms to cellular terpene precursors and thereby expand the accessible chemical space of the products. Here we present examples for the application of such enzymes to...... hiện toàn bộ
Quantitative Analyse der ProteomdynamikBIOspektrum - Tập 17 - Trang 756-759 - 2011
Marieluise Kirchner, Matthias Selbach
Proteine, mit ihren zell- und gewebespezifischen Funktionen, unterliegen einer ständigen Dynamik mit komplexen Auswirkungen auf ganze zelluläre Netzwerke. Diese systematisch zu erfassen und zu verstehen, ist das Ziel der quantitativen in vivo-Proteomanalyse.
Tierische Proteinhydrolysate als N-Quelle für die MilchsäurefermentationBIOspektrum - Tập 21 - Trang 228-229 - 2015
Boris Winter, Axel Höhling, Joachim Venus
Polylactic acid, a biodegradable polymer, is an ecological alternative for petroleum-derived plastics. The biotechnological production of its precursor lactic acid demands complex carbon and nitrogen sources significantly defining the fermentation costs. Whereas a variety of waste streams have already been utilized as carbon providing substrates, there is still no cheap alternative for common pept...... hiện toàn bộ
Schwerhörigkeit im Alter: Was steckt dahinter?BIOspektrum - Tập 29 Số 4 - Trang 341-344 - 2023
Christine Köppl, Georg M. Klump
AbstractAge-related hearing loss is of increasing concern in our ageing society. However, a causal understanding of the manifold degenerative processes in the cochlea and auditory brain, and their relation to specific hearing problems, is still in its infancy. Gerbils that are trained to perform auditory tasks show very similar auditory perception to humans, includ...... hiện toàn bộ
Planctomyceten–außergewöhnlich, aber bakteriell: ein ParadigmenwechselBIOspektrum - Tập 24 Số 6 - Trang 593-595 - 2018
Sandra Wiegand, Christian Jogler
Abstract
Amongst the kingdom bacteria, the phylum Planctomycetes is most conspicuous. Planctomycetes seemed to lack the universal bacterial peptidoglycan cell wall, while their cytosol appeared compartmentalized, including a nucleus-like structure. Thus, Planctomycetes were seen as ‘missing link’ between pro- and eukaryotes. However, with the advent of ge...... hiện toàn bộ