Standardisierte mikroRNA-Analytik — die große Chance für Biomarkerstudien?BIOspektrum - - 2020
Maria Fauth, Meike J. Saul
AbstractCirculating microRNAs (miRs) represent promising diagnostic and
prognostic biomarkers for various diseases. Despite the high number of biomarker
studies, the results of these studies are hardly reproducible. This makes it
difficult to transfer the results into clinical application. In this context,
acceptance criteria for the quantification of miRs by reverse transcription
quantitative rea... hiện toàn bộ
Zellen des Immunsystems: vom Polarkreis ins AllBIOspektrum - Tập 17 - Trang 437-439 - 2011
Liliana E. Layer, Oliver Ullrich
Das Immunsystem gehört auf einem Raumflug zu den am stärksten beeinträchtigten
Systemen des menschlichen Körpers. Die Ursache dieser Störung liegt
wahrscheinlich auf Ebene der Zellen. Experimente an Bord einer
TEXUS-Forschungsrakete sollen nun Aufschluss hierüber geben.
Ultraschallbasiertes Liquid-Handling in der WirkstoffforschungBIOspektrum - Tập 20 - Trang 419-420 - 2014
Rainer Heller, Jan Carsten Pieck
Acoustic liquid handling plays an increasing role as alternative to classic
pipette tip or pin tool based liquid handling systems. This new method allows a
precise, contact-free transfer in the sub-microlitre range, directly from a
compound storage into an assay plate without intermediate dilution steps. The
sound based transfer technology of acoustic liquid handling creates new quality
requiremen... hiện toàn bộ
Abseits der Regel — Terpene mit ungewöhnlichen KohlenstoffgerüstenBIOspektrum - Tập 28 - Trang 335-337 - 2022
Markus Buchhaupt
The natural substance class of terpenoids covers an extremely wide range of
different structures, although their building block repertoire is strongly
limited. Methyltransferases from bacterial natural product pathways can add
carbon atoms to cellular terpene precursors and thereby expand the accessible
chemical space of the products. Here we present examples for the application of
such enzymes to... hiện toàn bộ
Anwendungen der Kabelbakterien in der Umwelt- und BiotechnologieBIOspektrum - Tập 30 - Trang 12-15 - 2024
Vincent Scholz, Tillmann Lueders
Cable bacteria are living electric wires, exerting remarkable effects on their
surroundings. Despite still refusing pure culture isolation, their biological
conductivity and their impact on aquatic sediments give rise to interesting
application prospects in environmental and bio-engineering, including
bioremediation, the mitigation of greenhouse gas emissions, and bioelectronics.
Here, we summariz... hiện toàn bộ
Erfolgreiche Generierung synthetischer MagnetbakterienBIOspektrum - Tập 30 - Trang 70-70 - 2024
Tom Haufschild
Magnetosomen sind bakterielle Organellen, die magnetische Nanokristalle
synthetisieren und in diversen bakteriellen Phyla vorkommen. Lediglich 30 Gene
sind hierfür erforderlich. Der Transfer dieser Gene in nicht-magnetotaktische
Bakterien war bislang nur begrenzt möglich. Nun ist es einem Team aus Bayreuth
gelungen, Magnetosomen in sieben Pseudomonadota-Stämme zu exprimieren und zu
analysieren.