Trügerische Etiketten für Signalproteine

Ullrich A, Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61:203–212

Auger KR, Serunian LA, Soltoff SP et al. (1989) PDGFdependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57:167–175

Patrucco E, Notte A, Barberis L et al. (2004) PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell 118:375–387

Perino A, Ghigo A, Ferrero E et al. (2011) Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110gamma. Mol Cell 42:84–95

Schmidt C, Schneble N, Muller JP et al. (2013) Phosphoinositide 3-kinase gamma mediates microglial phagocytosis via lipid kinase-independent control of cAMP. Neurosci 233:44–53

Xu H, Littman DR (1993) A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74:633–643

Putzke AP, Hikita ST, Clegg DO et al. (2005) Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development 132:3185–3195

Chen X, Zhang J, Lee J et al. (2006) A kinase-independent function of c-Abl in promoting proteolytic destruction of damaged DNA binding proteins. Mol Cell 22:489–499

Shaw AS, Filbert EL (2009) Scaffold proteins and immunecell signalling. Nat Rev Immunol 9:47–56

Dombroski D, Houghtling RA, Labno CM et al. (2005) Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. J Immunol 174:1385–1392

Speroni J, Federico MB, Mansilla SF et al. (2012) Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA. Proc Natl Acad Sci USA 109:7344–7349