Ultraschallbasiertes Liquid-Handling in der Wirkstoffforschung

BIOspektrum - Tập 20 - Trang 419-420 - 2014
Rainer Heller1, Jan Carsten Pieck2
1Greiner Bio-One Gmbh, Frickenhausen, Germany
2Merck KGaA, Darmstadt, Germany

Tóm tắt

Acoustic liquid handling plays an increasing role as alternative to classic pipette tip or pin tool based liquid handling systems. This new method allows a precise, contact-free transfer in the sub-microlitre range, directly from a compound storage into an assay plate without intermediate dilution steps. The sound based transfer technology of acoustic liquid handling creates new quality requirements for microplates used in compound or sample storage. The microplate bottom thickness homogeneity and the selected material do have major impact on the transfer process.