Archives of Pathology and Laboratory Medicine
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Implementation of Digital Pathology Offers Clinical and Operational Increase in Efficiency and Cost Savings
Archives of Pathology and Laboratory Medicine - Tập 143 Số 12 - Trang 1545-1555 - 2019
Context.—Digital pathology (DP) implementations vary in scale, based on aims of
intended operation. Few laboratories have completed a full-scale DP
implementation, which may be due to high overhead costs that disrupt the
traditional pathology workflow. Neither standardized criteria nor benchmark data
have yet been published showing practical return on investment after
implementing a DP platform.Ob...
Aggressive Angiomyxoma
Archives of Pathology and Laboratory Medicine - Tập 136 Số 2 - Trang 217-221 - 2012
Aggressive angiomyxoma is a rare mesenchymal tumor that most commonly arises in
the vulvovaginal region, perineum, and pelvis of women. The term aggressive
emphasizes the often infiltrative nature of the tumor and its frequent
association with local recurrence. Patients often present with nonspecific
symptoms which are frequently misdiagnosed with more common entities, such as a
Bartholin cyst, li...
Blood Management
Archives of Pathology and Laboratory Medicine - Tập 131 Số 5 - Trang 695-701 - 2007
AbstractContext.—We provide an overview of the principles of blood management:
the appropriate use of blood and blood components, with a goal of minimizing
their use.Objective.—To review the strategies that exploit combinations of
surgical and medical techniques, technologic devices, and pharmaceuticals, along
with an interdisciplinary team approach that combines specialists who are expert
at mini...
Segmental Tandem Triplication of the MLL Gene in an Intravascular Large B-Cell Lymphoma With Multisystem Involvement: A Comprehensive Morphologic, Immunophenotypic, Cytogenetic, and Molecular Cytogenetic Antemortem Study
Archives of Pathology and Laboratory Medicine - Tập 133 Số 9 - Trang 1477-1482 - 2009
Abstract An association between intravascular large B-cell lymphoma (IVLBCL) and
the mixed lineage leukemia (MLL) gene has never been demonstrated. Here, we
report an IVLBCL in a 47-year-old Asian man. Morphologically, the atypical
lymphoid infiltrate was entirely confined in the lumina of capillaries, small
vessels, and sinusoidal space. Within the kidney, the neoplastic lymphoid cells
exhibited ...
Erdheim-Chester Disease: A Unique Presentation With Liver Involvement and Vertebral Osteolytic Lesions
Archives of Pathology and Laboratory Medicine - Tập 127 Số 8 - Trang e337-e339 - 2003
Abstract Erdheim-Chester disease is a very rare xanthogranulomatous,
non-Langerhans cell systemic histiocytosis with an unknown etiology and
pathogenesis. Histologically, it is characterized by a diffuse infiltration with
large, foamy histiocytes, rare Touton-like giant cells, lymphocytic aggregates,
and fibrosis. The histiocytes differ from the Langerhans cell group in
ontogenesis, immunohistoche...
Waterhouse-Friderichsen Syndrome Secondary to Capnocytophaga canimorsus Septicemia and Demonstration of Bacteremia by Peripheral Blood Smear
Archives of Pathology and Laboratory Medicine - Tập 124 Số 6 - Trang 859-863 - 2000
Abstract Waterhouse-Friderichsen syndrome caused by Capnocytophaga canimorsus
septicemia was fatal in a previously healthy 47-year-old woman. The patient died
suddenly in less than 12 hours after presentation, in spite of supportive
measures, including ventilation, antibiotic coverage, pressor therapy, and
multiple transfusions of blood products. The diagnosis of infection due to an
unusual organi...
Prognostic Significance of Histomorphologic Parameters in Diffuse Malignant Peritoneal Mesothelioma
Archives of Pathology and Laboratory Medicine - Tập 130 Số 11 - Trang 1654-1661 - 2006
Abstract Context.—Diffuse malignant peritoneal mesothelioma is currently
regarded as a rare and lethal primary tumor arising from the peritoneal
membrane. In the past, treatment plans with variable combinations of surgery and
systemic chemotherapy were associated with a median survival of approximately 1
year. Standardized treatments using cytoreductive surgery and perioperative
intraperitoneal ch...
The Azzopardi Phenomenon
Archives of Pathology and Laboratory Medicine - Tập 127 Số 9 - Trang 1231-1231 - 2003
Perineurioma: A Distinctive and Underrecognized Peripheral Nerve Sheath Neoplasm
Archives of Pathology and Laboratory Medicine - Tập 131 Số 4 - Trang 625-636 - 2007
AbstractContext.—Perineuriomas are benign peripheral nerve sheath neoplasms
composed of perineurial cells with characteristic immunohistochemical and
ultrastructural features. They have been traditionally classified into two main
types according to their location—intraneural and extraneural—and overlap
histologically with many other tumors, which may be diagnostically challenging
to general surgic...
Colorectal Carcinoma Nodal Staging
Archives of Pathology and Laboratory Medicine - Tập 127 Số 6 - Trang 673-679 - 2003
AbstractContext.—Nodal staging accuracy is important for prognosis and selection
of patients for chemotherapy. Sentinel lymph node (SLN) mapping improves staging
accuracy in breast cancer and melanoma and is being investigated for colorectal
carcinoma.Objective.—To assess pathologic aspects of SLN staging for colon
cancer.Design.—Sentinel lymph nodes were identified with a dual
surgeon-pathologist...
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