Archives of Pathology and Laboratory Medicine

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Implementation of Digital Pathology Offers Clinical and Operational Increase in Efficiency and Cost Savings
Archives of Pathology and Laboratory Medicine - Tập 143 Số 12 - Trang 1545-1555 - 2019
Matthew G. Hanna, Victor E. Reuter, Jennifer Samboy, Christine England, Lorraine Corsale, Samson W. Fine, Narasimhan P. Agaram, Evangelos Stamelos, Yukako Yagi, Meera Hameed, David S. Klimstra, S. Joseph Sirintrapun
Context.—Digital pathology (DP) implementations vary in scale, based on aims of intended operation. Few laboratories have completed a full-scale DP implementation, which may be due to high overhead costs that disrupt the traditional pathology workflow. Neither standardized criteria nor benchmark data have yet been published showing practical return on inv...... hiện toàn bộ
Aggressive Angiomyxoma
Archives of Pathology and Laboratory Medicine - Tập 136 Số 2 - Trang 217-221 - 2012
Brian J. Sutton, Jennifer Laudadio
Aggressive angiomyxoma is a rare mesenchymal tumor that most commonly arises in the vulvovaginal region, perineum, and pelvis of women. The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with local recurrence. Patients often present with nonspecific symptoms which are frequently misdiagnosed with more common entities, such as a Bartholin ...... hiện toàn bộ
Blood Management
Archives of Pathology and Laboratory Medicine - Tập 131 Số 5 - Trang 695-701 - 2007
Lawrence T. Goodnough, Aryeh Shander
AbstractContext.—We provide an overview of the principles of blood management: the appropriate use of blood and blood components, with a goal of minimizing their use.Objective.—To review the strategies that exploit combinations of surgical and medical techniques, technologic devices, and pharmaceuticals, along with an interdisciplinary team approac...... hiện toàn bộ
Segmental Tandem Triplication of the MLL Gene in an Intravascular Large B-Cell Lymphoma With Multisystem Involvement: A Comprehensive Morphologic, Immunophenotypic, Cytogenetic, and Molecular Cytogenetic Antemortem Study
Archives of Pathology and Laboratory Medicine - Tập 133 Số 9 - Trang 1477-1482 - 2009
Jeremy Deisch, Franklin“Buddy” Fuda, Weina Chen, Nitin J. Karandikar, Arnaldo Arbini, Xin J. Zhou, Huan‐You Wang
Abstract An association between intravascular large B-cell lymphoma (IVLBCL) and the mixed lineage leukemia (MLL) gene has never been demonstrated. Here, we report an IVLBCL in a 47-year-old Asian man. Morphologically, the atypical lymphoid infiltrate was entirely confined in the lumina of capillaries, small vessels, and sinusoidal space. Within the ...... hiện toàn bộ
Erdheim-Chester Disease: A Unique Presentation With Liver Involvement and Vertebral Osteolytic Lesions
Archives of Pathology and Laboratory Medicine - Tập 127 Số 8 - Trang e337-e339 - 2003
Doina Ivan, Antonio Galvao Neto, Luciano B. Lemos, Arpan Gupta
Abstract Erdheim-Chester disease is a very rare xanthogranulomatous, non-Langerhans cell systemic histiocytosis with an unknown etiology and pathogenesis. Histologically, it is characterized by a diffuse infiltration with large, foamy histiocytes, rare Touton-like giant cells, lymphocytic aggregates, and fibrosis. The histiocytes differ from the Lang...... hiện toàn bộ
Waterhouse-Friderichsen Syndrome Secondary to Capnocytophaga canimorsus Septicemia and Demonstration of Bacteremia by Peripheral Blood Smear
Archives of Pathology and Laboratory Medicine - Tập 124 Số 6 - Trang 859-863 - 2000
Imran Mirza, John H. Wolk, Lajos Barna Tóth, Peter Rostenberg, Ramon Kranwinkel, Steven Sieber
Abstract Waterhouse-Friderichsen syndrome caused by Capnocytophaga canimorsus septicemia was fatal in a previously healthy 47-year-old woman. The patient died suddenly in less than 12 hours after presentation, in spite of supportive measures, including ventilation, antibiotic coverage, pressor therapy, and multiple transfusions of blood products. The...... hiện toàn bộ
Prognostic Significance of Histomorphologic Parameters in Diffuse Malignant Peritoneal Mesothelioma
Archives of Pathology and Laboratory Medicine - Tập 130 Số 11 - Trang 1654-1661 - 2006
Carlos A. Cerruto, Erwin A. Brun, David Chang, Paul H. Sugarbaker
Abstract Context.—Diffuse malignant peritoneal mesothelioma is currently regarded as a rare and lethal primary tumor arising from the peritoneal membrane. In the past, treatment plans with variable combinations of surgery and systemic chemotherapy were associated with a median survival of approximately 1 year. Standardized treatments using cytoreduct...... hiện toàn bộ
The Azzopardi Phenomenon
Archives of Pathology and Laboratory Medicine - Tập 127 Số 9 - Trang 1231-1231 - 2003
Bobbi S. Pritt, Kumarasen Cooper
Perineurioma: A Distinctive and Underrecognized Peripheral Nerve Sheath Neoplasm
Archives of Pathology and Laboratory Medicine - Tập 131 Số 4 - Trang 625-636 - 2007
Ricardo Macarenco, Fred Ellinger, André M. Oliveira
AbstractContext.—Perineuriomas are benign peripheral nerve sheath neoplasms composed of perineurial cells with characteristic immunohistochemical and ultrastructural features. They have been traditionally classified into two main types according to their location—intraneural and extraneural—and overlap histologically with many other tumors, which may be diagnostica...... hiện toàn bộ
Colorectal Carcinoma Nodal Staging
Archives of Pathology and Laboratory Medicine - Tập 127 Số 6 - Trang 673-679 - 2003
Roderick R. Turner, Dean T. Nora, Christine Schammel, Anton J. Bilchik
AbstractContext.—Nodal staging accuracy is important for prognosis and selection of patients for chemotherapy. Sentinel lymph node (SLN) mapping improves staging accuracy in breast cancer and melanoma and is being investigated for colorectal carcinoma.Objective.—To assess pathologic aspects of SLN staging for colon cancer.Design.—S...... hiện toàn bộ
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