Annual Review of Biomedical Engineering

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3-D Visualization in Biomedical Applications
Annual Review of Biomedical Engineering - Tập 1 Số 1 - Trang 377-399 - 1999
Richard A. Robb
▪ Abstract  Visualizable objects in biology and medicine extend across a vast range of scale, from individual molecules and cells through the varieties of tissue and interstitial interfaces to complete organs, organ systems, and body parts. These objects include functional attributes of these systems, such as biophysical, biomechanical, and physiological properties. Visualization in three...... hiện toàn bộ
Physics and Applications of Microfluidics in Biology
Annual Review of Biomedical Engineering - Tập 4 Số 1 - Trang 261-286 - 2002
David J. Beebe, Glennys Mensing, Gregg B. Walker
▪ Abstract  Fluid flow at the microscale exhibits unique phenomena that can be leveraged to fabricate devices and components capable of performing functions useful for biological studies. The physics of importance to microfluidics are reviewed. Common methods of fabricating microfluidic devices and systems are described. Components, including valves, mixers, and pumps, capable of controlli...... hiện toàn bộ
Assessing Cartilage Biomechanical Properties: Techniques for Evaluating the Functional Performance of Cartilage in Health and Disease
Annual Review of Biomedical Engineering - Tập 19 Số 1 - Trang 27-55 - 2017
Benjamin A. Lakin, Brian D. Snyder, Mark W. Grinstaff
Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due to overloading. During joint articulation, hyaline cartilage must withstand high loads while maintaining low friction to prevent wear and tissue loss. Thus, cartilage compressive stiffness and the coefficient of friction are important indicators of the tissue's functional performance. These mechani...... hiện toàn bộ
Drugging Membrane Protein Interactions
Annual Review of Biomedical Engineering - Tập 18 Số 1 - Trang 51-76 - 2016
Hang Yin, Aaron D. Flynn
The majority of therapeutics target membrane proteins, accessible on the surface of cells, to alter cellular signaling. Cells use membrane proteins to transduce signals into cells, transport ions and molecules, bind cells to a surface or substrate, and catalyze reactions. Newly devised technologies allow us to drug conventionally “undruggable” regions of membrane proteins, enabling modulat...... hiện toàn bộ
The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
Annual Review of Biomedical Engineering - Tập 14 Số 1 - Trang 1-16 - 2012
Alexandre Albanese, Peter S. Tang, Warren C. W. Chan
An understanding of the interactions between nanoparticles and biological systems is of significant interest. Studies aimed at correlating the properties of nanomaterials such as size, shape, chemical functionality, surface charge, and composition with biomolecular signaling, biological kinetics, transportation, and toxicity in both cell culture and animal experiments are under way. These...... hiện toàn bộ
DNA Microarray Technology: Devices, Systems, and Applications
Annual Review of Biomedical Engineering - Tập 4 Số 1 - Trang 129-153 - 2002
Michael J. Heller
▪ Abstract  In this review, recent advances in DNA microarray technology and their applications are examined. The many varieties of DNA microarray or DNA chip devices and systems are described along with their methods for fabrication and their use. This includes both high-density microarrays for high-throughput screening applications and lower-density microarrays for various diagnostic app...... hiện toàn bộ
Microrobots for Minimally Invasive Medicine
Annual Review of Biomedical Engineering - Tập 12 Số 1 - Trang 55-85 - 2010
Bradley J. Nelson, I. Kaliakatsos, Jake J. Abbott
Photoacoustic Microscopy and Computed Tomography: From Bench to Bedside
Annual Review of Biomedical Engineering - Tập 16 Số 1 - Trang 155-185 - 2014
Lihong V. Wang, Liang Gao
Photoacoustic imaging (PAI) of biological tissue has seen immense growth in the past decade, providing unprecedented spatial resolution and functional information at depths in the optical diffusive regime. PAI uniquely combines the advantages of optical excitation and those of acoustic detection. The hybrid imaging modality features high sensitivity to optical absorption and wide scalabil...... hiện toàn bộ
Mechano-Electrochemical Properties Of Articular Cartilage: Their Inhomogeneities and Anisotropies
Annual Review of Biomedical Engineering - Tập 4 Số 1 - Trang 175-209 - 2002
Van C. Mow, Xiao Guo
▪ Abstract  In this chapter, the recent advances in cartilage biomechanics and electromechanics are reviewed and summarized. Our emphasis is on the new experimental techniques in cartilage mechanical testing, new experimental and theoretical findings in cartilage biomechanics and electromechanics, and emerging theories and computational modeling of articular cartilage. The charged nature a...... hiện toàn bộ
Physicochemical Foundations and Structural Design of Hydrogels in Medicine and Biology
Annual Review of Biomedical Engineering - Tập 2 Số 1 - Trang 9-29 - 2000
Nikolaos A. Peppas, Yanbin Huang, Madeline Torres‐Lugo, Jennifer H. Ward, J. Zhang
▪ Abstract  Hydrogels are cross-linked hydrophilic polymers that can imbibe water or biological fluids. Their biomedical and pharmaceutical applications include a very wide range of systems and processes that utilize several molecular design characteristics. This review discusses the molecular structure, dynamic behavior, and structural modifications of hydrogels as well as the various ap...... hiện toàn bộ
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