American Association for the Advancement of Science (AAAS)
1946-6234
1946-6242
Cơ quản chủ quản: American Association for the Advancement of Science , AMER ASSOC ADVANCEMENT SCIENCE
Lĩnh vực:
Medicine (miscellaneous)
Các bài báo tiêu biểu
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Circulating tumor DNA can be used in a variety of clinical and investigational settings across tumor types and stages for screening, diagnosis, and identifying mutations responsible for therapeutic response and drug resistance.
Tập 6 Số 224 - 2014
Hidden Killers: Human Fungal Infections The lack of robust rapid diagnostic tests, safe and effective drugs, and preventative vaccines hampers treatment of patients with invasive fungal infections.
Tập 4 Số 165 - 2012
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors Lung cancers undergo dynamic genetic and histological changes upon developing resistance to EGFR inhibitors.
Tập 3 Số 75 - 2011
The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice A translational medicine pipeline is described where human gut microbial communities and diets are re-created in gnotobiotic mice and the impact on microbe and host is defined using metagenomics.
Tập 1 Số 6 - 2009
Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia CD19 CAR T cell therapy induces complete remissions in 88% of 16 adult patients with relapsed or refractory acute lymphoblastic leukemia.
Tập 6 Số 224 - 2014
The Placenta Harbors a Unique Microbiome Metagenomic approaches demonstrate that the human placenta is not sterile but harbors a unique microbiome.
Tập 6 Số 237 - 2014
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia Adoptively transferred gene-modified T cells expand in vivo, eliminate leukemic cells, and form functional memory cells in patients.
Tập 3 Số 95 - 2011
Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape Activated tumor-infiltrating lymphocytes may induce B7-H1 on melanocytes, which suggests adaptive resistance to antitumor immunity.
Tập 4 Số 127 - 2012
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia CAR T cells persist and sustain remissions in advanced chronic lymphocytic leukemia.
Tập 7 Số 303 - 2015
Temporal Dynamics of the Human Vaginal Microbiota The vaginal microbiome is dynamic, varying over time in composition and function with implications for women’s health.
Tập 4 Số 132 - 2012