American Association for the Advancement of Science (AAAS)
1946-6234
1946-6242
Cơ quản chủ quản: American Association for the Advancement of Science , AMER ASSOC ADVANCEMENT SCIENCE
Lĩnh vực:
Medicine (miscellaneous)
Phân tích ảnh hưởng
Thông tin về tạp chí
Các bài báo tiêu biểu
Total-body imaging: Transforming the role of positron emission tomography The first total-body positron emission tomography (TB-PET) scanner represents a radical change for experimental medicine and diagnostic health care.
Tập 9 Số 381 - 2017
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels A machine learning method can predict loss- versus gain-of-function effects of human genetic variants in disease-associated ion channels.
Tập 12 Số 556 - 2020
PGC-1α Rescues Huntington’s Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function PGC-1α rescues Huntington’s disease neurodegeneration by reducing reactive oxygen species and inducing a master regulator of autophagy.
Tập 4 Số 142 - 2012
Rapamycin and Alzheimer’s disease: Time for a clinical trial? In this Perspective, the authors propose that clinical testing of rapamycin in patients with Alzheimer’s disease is long overdue.
Tập 11 Số 476 - 2019
Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys Engineered long-acting GDF15-Fc fusion molecules reduce food intake and body weight and improve metabolic profiles in animal models of obesity.
Tập 9 Số 412 - 2017
Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia CD19 CAR T cell therapy induces complete remissions in 88% of 16 adult patients with relapsed or refractory acute lymphoblastic leukemia.
Tập 6 Số 224 - 2014
Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells Adoptively transferred chimeric antigen receptor T cells have stable stem cell–like persistence for at least a decade and more than 500 years of patient safety.
Tập 4 Số 132 - 2012
Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells T cells engineered to express affinity-enhanced TCRs directed to a MAGE A3 peptide cross-react with a similar, but unrelated, self-peptide.
Tập 5 Số 197 - 2013
Mitigation of tracheobronchomalacia with 3D-printed personalized medical devices in pediatric patients Patient-specific, image-based design coupled with 3D biomaterial printing produced personalized implants for treatment of collapsed airways in patients with tracheobronchomalacia.
Tập 7 Số 285 - 2015
Testing the Right Target and Right Drug at the Right Stage Drugs aimed at the initial stages of the Alzheimer’s disease pathology should be tested a decade before the onset of dementia.
Tập 3 Số 111 - 2011