Oxidative Stress in the Pathogenesis of Skin Disease

Amstad, 1991, The balance between Cu, Zn-superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress, Biochemistry, 30, 9305, 10.1021/bi00102a024

Anderson, 1995, Metabolic requirements for induction of contact hypersensitivity to immunotoxic polyaromatic hydrocarbons, J Immunol, 155, 3530, 10.4049/jimmunol.155.7.3530

Athar, 1989, A novel mechanism for the generation of superoxide anions in hematoporphyrin derivative-mediated cutaneous photosensitization. Activation of the xanthine oxidase pathway, J Clin Invest, 83, 1137, 10.1172/JCI113993

Athar, 1989, Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds, Carcinogenesis, 10, 1841, 10.1093/carcin/10.10.1841

Athar, 1988, In situ evidence for the involvement of superoxide anions in cutaneous porphyrin photosensitization, Biochem Biophys Res Commun, 151, 1054, 10.1016/S0006-291X(88)80472-8

Bachelor, 2004, UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression, Semin Cancer Biol, 14, 131, 10.1016/j.semcancer.2003.09.017

Bickers, 2000, Novel approaches to chemoprevention of skin cancer, J Dermatol, 27, 691, 10.1111/j.1346-8138.2000.tb02259.x

Bickers, 1982, Epidermis: a site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed-function oxidase and epoxide hydrolase activity, Mol Pharmacol, 21, 239

Bickers, 1978, Human skin aryl hydrocarbon hydroxylase. Induction by coal tar, J Clin Invest, 62, 1061, 10.1172/JCI109211

Bickers, 1974, Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), J Pharmacol Exp Ther, 188, 300

Black, 2004, Reassessment of a free radical theory of cancer with emphasis on ultraviolet carcinogenesis, Integr Cancer Ther, 3, 279, 10.1177/1534735404270612

Black, 2004, ROS: a step closer to elucidating their role in the etiology of light-induced skin disorders, J Invest Dermatol, 122, xiii, 10.1111/j.0022-202X.2004.22625.x

Boissy, 2004, On the etiology of contact/occupational vitiligo, Pigment Cell Res, 17, 208, 10.1111/j.1600-0749.2004.00130.x

Bowden, 2004, Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling, Nat Rev Cancer, 4, 23, 10.1038/nrc1253

Brenneisen, 2002, Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events, Ann NY Acad Sci, 973, 31, 10.1111/j.1749-6632.2002.tb04602.x

Briganti, 2003, Antioxidant activity, lipid peroxidation and skin diseases. What's new, J Eur Acad Dermatol Venereol, 17, 663, 10.1046/j.1468-3083.2003.00751.x

Cerutti, 1992, Oxidant carcinogenesis and antioxidant defense, Ann NY Acad Sci, 663, 158, 10.1111/j.1749-6632.1992.tb38659.x

Connor, 1987, Depletion of cutaneous glutathione by ultraviolet radiation, Photochem Photobiol, 46, 239, 10.1111/j.1751-1097.1987.tb04762.x

Curtin, 2004, Short-term in vitro and in vivo analyses for assessing the tumor-promoting potentials of cigarette smoke condensates, Toxicol Sci, 81, 14, 10.1093/toxsci/kfh172

Elchuri, 2005, CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life, Oncogene, 24, 367, 10.1038/sj.onc.1208207

Elmets, 1998, Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complex, Proc Natl Acad Sci USA, 95, 14915, 10.1073/pnas.95.25.14915

F'Guyer, 2003, Photochemoprevention of skin cancer by botanical agents, Photodermatol Photoimmunol Photomed, 19, 56, 10.1034/j.1600-0781.2003.00019.x

Filipe, 1997, Oxyradical-mediated clastogenic plasma factors in psoriasis: increase in clastogenic activity after PUVA, Photochem Photobiol, 66, 497, 10.1111/j.1751-1097.1997.tb03179.x

Fisher, 2002, Mechanisms of photoaging and chronological skin aging, Arch Dermatol, 138, 1462, 10.1001/archderm.138.11.1462

Golberg, 1962, Biochemical changes in the tissues of animals injected with iron. 3. Lipid peroxidation, Biochem J, 83, 291, 10.1042/bj0830291

Hanson, 1998, Epidermal trans-urocanic acid and the UV-A-induced photoaging of the skin, Proc Natl Acad Sci USA, 95, 10576, 10.1073/pnas.95.18.10576

Haralampus-Grynaviski, 2002, Photogeneration and quenching of reactive oxygen species by urocanic acid, J Am Chem Soc, 124, 3461, 10.1021/ja016902x

Iskander, 2005, Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis, Cancer Res, 65, 2054, 10.1158/0008-5472.CAN-04-3157

Iskander, 2004, Deficiency of NRH:quinone oxidoreductase 2 increases susceptibility to 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene-induced skin carcinogenesis, Cancer Res, 64, 5925, 10.1158/0008-5472.CAN-04-0763

Kaur, 2001, Patients with allergic and irritant contact dermatitis are characterized by striking change of iron and oxidized glutathione status in nonlesional area of the skin, J Invest Dermatol, 116, 886, 10.1046/j.0022-202x.2001.01374.x

Kawakubo, 1997, Acetylator phenotype in patients with p-phenylenediamine allergy, Dermatology, 195, 43, 10.1159/000245683

Kim, 2005, Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice, J Invest Dermatol, 124, 1318, 10.1111/j.0022-202X.2005.23747.x

Kim, 2005, An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis, Oncogene, 24, 1174, 10.1038/sj.onc.1208269

Kobayashi, 1991, Superoxide dismutase in psoriasis, squamous cell carcinoma and basal cell epithelioma: an immunohistochemical study, Br J Dermatol, 124, 555, 10.1111/j.1365-2133.1991.tb04950.x

Lee, 2003, Cyclooxygenases in the skin: pharmacological and toxicological implications, Toxicol Appl Pharmacol, 192, 294, 10.1016/S0041-008X(03)00301-6

Liebler, 2000, Effects of UV light and tumor promoters on endogenous vitamin E status in mouse skin, Carcinogenesis, 21, 221, 10.1093/carcin/21.2.221

Long, 2001, NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin, J Natl Cancer Inst, 93, 1166, 10.1093/jnci/93.15.1166

Lopez-Torres, 1994, Effect of age on antioxidants and molecular markers of oxidative damage in murine epidermis and dermis, J Invest Dermatol, 102, 476, 10.1111/1523-1747.ep12373032

Marks, 2003, Mouse skin as a model for cancer chemoprevention by nonsteroidal anti-inflammatory drugs, Recent Results Cancer Res, 163, 46, 10.1007/978-3-642-55647-0_5

Matos, 2005, Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line, Immunol Cell Biol, 83, 607, 10.1111/j.1440-1711.2005.01378.x

Maziere, 2003, Impairment of the EGF signaling pathway by the oxidative stress generated with UVA, Free Radic Biol Med, 34, 629, 10.1016/S0891-5849(02)01329-1

Nakamura, 1985, Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA, Carcinogenesis, 6, 229, 10.1093/carcin/6.2.229

Nelson, 2004, Mitochondrial redox control of matrix metalloproteinases, Free Radic Biol Med, 37, 768, 10.1016/j.freeradbiomed.2004.06.008

Nishigori, 2004, Role of reactive oxygen species in skin carcinogenesis, Antioxid Redox Signal, 6, 561, 10.1089/152308604773934314

O'Donovan, 2005, Azathioprine and UVA light generate mutagenic oxidative DNA damage, Science, 309, 1871, 10.1126/science.1114233

Okayama, 2005, Oxidative stress in allergic and inflammatory skin diseases, Curr Drug Targets Inflamm Allergy, 4, 517, 10.2174/1568010054526386

Oshima, 1976, Cystine metabolism in human fibroblasts. Comparison of normal, cystinotic, and gamma-glutamylcysteine synethetase-deficient cells, J Biol Chem, 251, 4287, 10.1016/S0021-9258(17)33294-5

Parrish, 2005, Immunosuppression, skin cancer, and ultraviolet A radiation, N Engl J Med, 353, 2712, 10.1056/NEJMcibr054224

Polte, 2004, Involvement of lipid peroxidation and organic peroxides in UVA-induced matrix metalloproteinase-1 expression, Free Radic Biol Med, 36, 1566, 10.1016/j.freeradbiomed.2004.04.003

Ramachandran, 2001, Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype, Pharmacogenetics, 11, 247, 10.1097/00008571-200104000-00008

Reelfs, 2004, Ultraviolet a radiation-induced immediate iron release is a key modulator of the activation of NF-kappaB in human skin fibroblasts, J Invest Dermatol, 122, 1440, 10.1111/j.0022-202X.2004.22620.x

Rotstein, 1988, Effect of exogenous glutathione on tumor progression in the murine skin multistage carcinogenesis model, Carcinogenesis, 9, 1547, 10.1093/carcin/9.9.1547

Ryter, 2000, The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties, Free Radic Biol Med, 28, 289, 10.1016/S0891-5849(99)00223-3

Sander, 2004, Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis, Int J Dermatol, 43, 326, 10.1111/j.1365-4632.2004.02222.x

Schulman, 1975, Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase, Biochem Biophys Res Commun, 65, 68, 10.1016/S0006-291X(75)80062-3

Shin, 2005, H2O2 accumulation by catalase reduction changes MAP kinase signaling in aged human skin in vivo, J Invest Dermatol, 125, 221, 10.1111/j.0022-202X.2005.23823.x

St Clair, 2005, Modulation of skin tumorigenesis by SOD, Biomed Pharmacother, 59, 209, 10.1016/j.biopha.2005.03.004

Stern, 1998, Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis, Arch Dermatol, 134, 1582, 10.1001/archderm.134.12.1582

Trenam, 1992, Skin inflammation: reactive oxygen species and the role of iron, J Invest Dermatol, 99, 675, 10.1111/1523-1747.ep12613740

Wiebel, 1975, Aryl hydrocarbon (benzo[a]pyrene) hydroxylase: a mixed-function oxygenase in mouse skin, J Invest Dermatol, 64, 184, 10.1111/1523-1747.ep12533351