Altered Patterns of Cutaneous Xenobiotic Metabolism in UVB-Induced Squamous Cell Carcinoma in SKH-1 Hairless Mice

Bickers, 1980, The skin as a site of drug and carcinogen metabolism, 95 Emmett, 1973, Ultraviolet radiation as a cause of skin tumors, CRC Crit Rev Toxicol, 2, 211, 10.3109/10408447309025703 Findlay, 1928, Ultraviolet light, and skin cancer, Lancet, 24, 1070, 10.1016/S0140-6736(00)84845-X Boutwell, 1978, 2, 49 Conney, 1982, Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: GHA Clowes Memorial Lecture, Cancer Res, 42, 4875 Sultatos, 1980, Enhanced drug metabolizing capacity within liver adjacent to human and rat liver tumors, Proc Natl Acad Sci USA, 77, 600, 10.1073/pnas.77.1.600 Mason, 1981, Aryl hydrocarbon hydroxylase activity in mouse, rat and human mammary tumors, Cancer Res, 41, 2778 Nebert, 1972, Aryl hydrocarbon hydroxylase induction by polycyclic aromatic hydrocarbons: simple antosomal trait in mouse, Nature, 236, 107 Hart, 1965, The stimulation of drug metabolism in various rat hepatomas, J Pharmacol Exp Ther, 149, 7 Adamson, 1961, The metabolism of drugs by hepatic tumors, Cancer Res, 21, 667 Morris, 1960, Some characteristics of transplantable rat hepatoma no. 5123 induced by ingestion of N-(2-fluorenyl)phthalmic acid, Cancer Res, 20, 1252 Bickers, 1982, Epidermis: a site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed function oxidase and epoxide hydrolase activity, Mol Pharmacol, 21, 239 Mukhtar, 1981, Drug metabolism in skin: comparative activity of the mixed function oxidases, epoxide hydrolase and glutathione-S-transferase in liver and skin of neonatal rat, Drug Metab Dispos, 9, 311 Pohl, 1976, Cytochrome P-450 content and mixed function oxidase activity in microsomes isolated from mouse skin, Drug Metab Dispos, 4, 442 Kates, 1970, Ribonucleic acid synthesis in vaccinia versus. I. The mechanism of synthesis and release of RNA in vaccinia cores, J Mol Biol, 50, 1, 10.1016/0022-2836(70)90100-2 Diamond, 1967, The initiation of 7,12-dimethylbenz(a)anthracene with cells sensitive and resistant to toxicity induced by the carcinogen, Cancer Res, 27, 890 Ashurst, 1982, The formation of benzo(a)pyrene-deoxyribonucleoside adducts in vivo and in vitro, Carcinogenesis, 3, 267, 10.1093/carcin/3.3.267 Perera, 1982, A pilot project in molecular cancer epidemiology: determination of benzo(a)pyrene-DNA adducts in animal and human tissues by immunoassay, Carcinogenesis, 3, 1405, 10.1093/carcin/3.12.1405 Santella, 1984, Monoclonal antibodies to DNA modified by a benzo(a)pyrene diol epoxide, Carcinogenesis, 5, 373, 10.1093/carcin/5.3.373 Nebert, 1968, Substrate inducible microsomal aryl hydrocarbon hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme, J Biol Chem, 243, 5242, 10.1016/S0021-9258(18)94485-6 Greenlee, 1978, An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8,-totrachlorodibenzo-p-dioxin, J Pharmacol Exp Ther, 205, 596 Jerina, 1977, Hepatic microsomal epoxide hydrase: a sensitive radiometric assay for hydration of arene oxides of carcinogenic aromatic hydrocarbons, Mol Pharmacol, 13, 342 Habig, 1974, Glutathione-S-transferase. The first step in mercapturic acid formation, J Biol Chem, 249, 7130, 10.1016/S0021-9258(19)42083-8 Omura, 1964, The carbon monoxide binding pigment of liver microsomes. Evidence for its hemoprotein nature, J Biol Chem, 239, 2370, 10.1016/S0021-9258(20)82244-3 Lowry, 1951, Protein measurement with Folin phenol reagent, J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6 Miyake, 1974, Abnormal microsomal cytochromes and electron transport in Morris hepatoma, J Biol Chem, 249, 1980, 10.1016/S0021-9258(19)42880-9 Mukhtar, 1982, Effect of topical application of defined constituents of coal tar on skin and liver aryl hydrocarbon hydroxylase and 7-ethoxycoumarin deethylase activities, Toxicol Appl Pharmacol, 64, 541, 10.1016/0041-008X(82)90251-4 LePage, 1960, 1, 440, 10.1159/000385946 Potter, 1961, Transplantable animal cancer, the primary standard, Cancer Res, 21, 1331 Goeckerman, 1931, Treatment of psoriasis; continued observations on the use of coal tar and ultraviolet light, Arch Dermatol, 24, 446 Bickers, 1978, Human skin aryl hydrocarbon hydroxylase, J Clin Invest, 62, 1061, 10.1172/JCI109211 Hodgson, 1948, Epithelioma following local treatment of pruritus ani with liquor picis carbonis, Br J Dermatol, 60, 282, 10.1111/j.1365-2133.1948.tb11303.x Henry, 1947, Occupational cutaneous cancer attributable to certain chemicals in industry, Br Med Bull, 4, 389, 10.1093/oxfordjournals.bmb.a072833 Berenblum, 1948, Liquor picis carbonis (BP), a carcinogenic agent, Br Med J, 2, 601, 10.1136/bmj.2.4577.601 Poel, 1957, Experimental carcinogenicity of coal tar fractions. The carcinogenicity of creosote oils, J Natl Cancer Inst, 18, 41 Kellerman, 1972, Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma, N Engl J Med, 289, 934, 10.1056/NEJM197311012891802 Burki, 1973, Induction of aryl hydrocarbon hydroxylase in mouse tissue from a high and low cancer strain and their hybrids, J Natl Cancer Inst, 50, 370, 10.1093/jnci/50.2.369 Levin, 1976, (±)-trans7,8-Dihydroxy-7,8-dihydrobenzo(a)pyrene: a potent skin carcinogen when applied topically to mice, Proc Natl Acad Sci USA, 73, 3867, 10.1073/pnas.73.11.3867 Slaga, 1979, Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diasteriomeric benzo(a)pyrene-7,8-diol-9,10-epoxides, Cancer Res, 39, 67 Epstein, 1961, The effect of ultraviolet light on chemical carcinogenesis, J Invest Dermatol, 36, 73, 10.1038/jid.1961.15